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1521por Ronchetti, Livia, Boubaker, Nouha Setti, Barba, Maddalena, Vici, Patrizia, Gurtner, Aymone, Piaggio, Giulia“…NETosis biomarkers, e.g., citH3, may integrate correlates of immunogenicity currently available (e.g., PD-L1 expression, TMB, TILs) and help select the subsets of patients who may most benefit from the use of the therapeutic weapons under discussion.…”
Publicado 2021
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1522por Sasaki, Shoichi“…Ninety patients with a UPDRS-III score of 3 or 4, including postural tremor, were evaluated by (123)I-FP-CIT SPECT (DaTscan), brain MRI, the Mini-Mental State Examination, and smell test. …”
Publicado 2021
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1523por Vincenzi, Paolo, Gaynor, Jeffrey J., Chen, Linda J., Figueiro, Jose, Morsi, Mahmoud, Selvaggi, Gennaro, Tekin, Akin, Vianna, Rodrigo, Ciancio, Gaetano“…Pre-operative hypoalbuminemia and longer CIT were included in the propensity score for receiving a drain and were associated with a significantly higher rate of developing a hematoma post-transplant. …”
Publicado 2021
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1524por Holm, Sverre, Kared, Hassen, Michelsen, Annika E, Kong, Xiang Yi, Dahl, Tuva B, Schultz, Nina H, Nyman, Tuula A, Fladeby, Cathrine, Seljeflot, Ingebjørg, Ueland, Thor, Stensland, Maria, Mjaaland, Siri, Goll, Guro Løvik, Nissen-Meyer, Lise Sofie, Aukrust, Pål, Skagen, Karolina, Gregersen, Ida, Skjelland, Mona, Holme, Pål A, Munthe, Ludvig A, Halvorsen, Bente“…Blood analyses showed activation of neutrophils and increased levels of circulating H3Cit, dsDNA, and myeloperoxidase–DNA complex. The thrombus had extensive infiltration of neutrophils, formation of neutrophil extracellular traps (NETs), and IgG deposits. …”
Publicado 2021
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1525“…CD66b(+) neutrophils and myeloperoxidase/citrullinated histone H3 (MPO/H3Cit)-labeled NETs were assessed by immunofluorescence, and the relationships with clinical and histopathologic features and patient outcome were evaluated. …”
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1526por Mierzchała-Pasierb, Magdalena, Lipińska-Gediga, Małgorzata, Fleszar, Mariusz G., Lewandowski, Łukasz, Serek, Paweł, Płaczkowska, Sylwia, Krzystek-Korpacka, Małgorzata“…The urine Gly-Pro concentration was significantly higher in septic shock than in sepsis. The serum Cit concentration was significantly lower in septic shock than in sepsis. …”
Publicado 2021
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1527“…The coauthorship relations in the analysis units of countries, organizations, and authors; the top 10 burst references; the document citation network; and the author’s keywords co-occurrence overlay map were visualized by bibliometric software including the website (https://bibliometric.com/), VOSviewer, CiteSpace, and CitNetExplorer. Results: From 1974 to the present, the most high-yield publication year, country, institute, author, and journal were 2020 (n = 222), France (n = 522), Netherlands Pharmacovigilance Centre Lareb (n = 82), Jean–Louis Montastruc (n = 125), Drug Safety (n = 384), respectively, in all 2,128 articles. …”
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1528por Nuuttila, Simo, Eklund, Mikael, Joutsa, Juho, Jaakkola, Elina, Mäkinen, Elina, Honkanen, Emma A., Lindholm, Kari, Noponen, Tommi, Ihalainen, Toni, Murtomäki, Kirsi, Nojonen, Tanja, Levo, Reeta, Mertsalmi, Tuomas, Scheperjans, Filip, Kaasinen, Valtteri“…GR was performed on 161 patients with PD, 47 patients with essential tremor (ET) and 40 healthy controls immediately prior to dopamine transporter (DAT) [(123)I]FP-CIT SPECT scanning. The binding ratios were investigated with consideration of the GR result (normal/abnormal). …”
Publicado 2021
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1529“…Strategies to improve the police response include Crisis Intervention Team (CIT) training and various forms of co-response models neither of which have been subjected to comprehensive evaluations, particularly as to cost-efficiency. …”
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1530“…The following data were recorded: patient ID, GPCOG/6CIT score, final diagnosis, CID prescriptions and CID review. …”
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1531por Dahmen, Jari, Vreeken, Jelmer T., Stornebrink, Tobias, Emanuel, Kaj, Stufkens, Sjoerd A., Kerkhoffs, Gino“…The success rate of BMS was significantly lower than FIX, OCT and CIT. There were no significant differences in success rates between the other treatment options. …”
Publicado 2022
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1532“…All patients underwent positron emission tomography (PET) with (18)F-N-(3-fluoropropyl)-2beta-carbon ethoxy-3beta-(4-iodophenyl) nortropane ((18)F-FP-CIT), and the regional standardized uptake value ratios (SUVRs) were analyzed with a volume-of-interest template among the groups. …”
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1533por Evans, Nick, Grygorash, Ruslan, Williams, Paul, Kyle, Andrew, Kantner, Terrence, Pathak, Ravindra, Sheng, XiaoBo, Simoes, Fabio, Makwana, Hiteshri, Resende, Ricardo, de Juan, Elena, Jenkins, Alan, Morris, David, Michelet, Aurelie, Jewitt, Frances, Rudge, Felicity, Camper, Nicolas, Manin, Anaïs, McDowell, William, Pabst, Martin, Godwin, Antony, Frigerio, Mark, Bird, Matthew“…Bis-sulfone based disulfide rebridging reagents bearing Val-Cit-PABC-MMAE linker-payloads were synthesized with a panel of cyclodextrins and crown ethers integrated into their structures via a glutamic acid branching point. …”
Publicado 2022
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1534“…MYB, RRM2, ERG, CENPF, CIT, and TOP2A are potential drug targets for treatment. …”
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1535por Agathangelidis, Andreas, Chatzidimitriou, Anastasia, Chatzikonstantinou, Thomas, Tresoldi, Cristina, Davis, Zadie, Giudicelli, Véronique, Kossida, Sofia, Belessi, Chrysoula, Rosenquist, Richard, Ghia, Paolo, Langerak, Anton W., Davi, Frédéric, Stamatopoulos, Kostas“…Importantly, independent studies have documented that IGHV SHM status is also a predictor of responses to therapy, including both chemoimmunotherapy (CIT) and novel, targeted agents. Moreover, immunogenetic analysis in CLL has revealed that different patients may express (quasi)identical, stereotyped B cell receptor immunoglobulin (BcR IG) and are classified into subsets based on this common feature. …”
Publicado 2022
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1536“…This analysis indicates that the MgHCit and MgCit(−) complexes have the main influence on the nucleation and growth of struvite in artificial urine in the presence of phosphoric acid. …”
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1537por Lee, Seung Hyun, Kim, Mina, Lee, Jooyoung, Kim, Jae-Woo, Kim, Mi Sun, Jo, Sungyang, Jeon, Sang Ryong, Chung, Sun Ju“…The patients underwent preoperative [(18)F] FP-CIT positron emission tomography before DBS surgery. …”
Publicado 2022
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1538por Li, Yiting, Kumar, Anikender, Hamilton, Sofia, Lea, Jeremy D., Harvey, John, Kleeman, Michael J.“…A second set of simulations used the UCD/CIT CTM with spatial resolution ranging from 4 km to 24 km over domains ranging in size from 98,000 km(2) to 1,000,000 km(2). …”
Publicado 2022
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1539por Beitinjaneh, Amer, Kaufman, Adrienne, Wang, Yucai, Jain, Preetesh, Srour, Samer A, Wang, Michael“…For years, upfront autologous hematopoietic cell transplant (auto-HCT) has been the standard of care for younger and physically fit mantle cell lymphoma (MCL) patients after chemoimmunotherapy (CIT) induction. Bruton’s tyrosine kinase (BTK) inhibitors have proven to be excellent salvage therapies, but their durability remains a question, especially in high-risk (HR) MCL. …”
Publicado 2022
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1540por Tang, Qiqi, Liang, Beibei, Zhang, Lisha, Li, Xuhui, Li, Hengyu, Jing, Wei, Jiang, Yingjie, Zhou, Felix, Zhang, Jian, Meng, Yanchun, Yang, Xinhua, Yang, Hao, Huang, Gang, Zhao, Jian“…Clinically, the expression of CCDC25 was positively correlated with the expression of 3-hydroxy-3-methylglutaryl-CoAreductase (HMRCG), and citrullinated histone H3 (H3cit), in tissues from breast cancer patients. High expression of CCDC25 and HMGCR was related with worse prognosis in breast cancer patients. …”
Publicado 2022
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