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441“…We show that initial recruitment of SRP receptor (SR) selectively enhances the affinity of SRP for correct cargos, thus committing SRP-dependent substrates to the pathway. …”
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442“…Commitment is a cultural dependent variable. Some organizational and socio-cultural factors are counted as the drivers of professional commitment. …”
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443por Sinha, Abhinav, Hughes, Katie R., Modrzynska, Katarzyna K., Otto, Thomas D., Pfander, Claudia, Dickens, Nicholas J., Religa, Agnieszka A., Bushell, Ellen, Graham, Anne L., Cameron, Rachael, Kafsack, Bjorn F.C., Williams, April E., Llinas, Manuel, Berriman, Matthew, Billker, Oliver, Waters, Andrew P.“…Commitment to and completion of sexual development are essential for malaria parasites (protists of the genus Plasmodium) to be transmitted through mosquitoes(1). …”
Publicado 2014
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444por Liu, Xili, Wang, Xin, Yang, Xiaojing, Liu, Sen, Jiang, Lingli, Qu, Yimiao, Hu, Lufeng, Ouyang, Qi, Tang, Chao“…In this study, we show that in budding yeast, the decision of cell cycle commitment (Start) is determined by the time integration of its triggering signal Cln3. …”
Publicado 2015
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445por Tarnawski, Laura, Xian, Xiaojie, Monnerat, Gustavo, Macaulay, Iain C., Malan, Daniela, Borgman, Andrew, Wu, Sean M., Fleischmann, Bernd K., Jovinge, Stefan“…By using single-cell expression profiling in early mouse embryonic hearts, we found that a combination of integrin alpha-1, alpha-5, alpha-6 and N-cadherin enables isolation of lineage committed murine cardiomyocytes. Additionally, we were able to separate trabecular cardiomyocytes from solid ventricular myocardium and atrial murine cells. …”
Publicado 2015
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446“…BACKGROUND: Several studies are available on organizational commitment of employees in different organizations. …”
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447“…Past research has produced evidence that parsing commitments strengthen over the processing of additional linguistic elements that are consistent with the commitments and undoing strong commitments takes more time than undoing weak commitments. …”
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448por Velten, Lars, Haas, Simon F., Raffel, Simon, Blaszkiewicz, Sandra, Islam, Saiful, Hennig, Bianca P., Hirche, Christoph, Lutz, Christoph, Buss, Eike C., Nowak, Daniel, Boch, Tobias, Hofmann, Wolf-Karsten, Ho, Anthony D., Huber, Wolfgang, Trumpp, Andreas, Essers, Marieke A.G., Steinmetz, Lars M.“…Here we integrated flow cytometric, transcriptomic and functional data at single-cell resolution to quantitatively map early differentiation of human HSCs towards lineage commitment. During homeostasis, individual HSCs gradually acquire lineage biases along multiple directions without passing through discrete hierarchically organized progenitor populations. …”
Publicado 2017
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449por Lemoine, Jean Frantz, Boncy, Jacques, Filler, Scott, Kachur, S. Patrick, Fitter, David, Chang, Michelle A.“…Haiti is committed to malaria elimination by 2020. Following a 2010 earthquake and cholera epidemic, Haiti capitalized on investments in its health system to refocus on malaria elimination. …”
Publicado 2017
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450“…CONCLUSION: The results highlighted that the nurses needed to be more competent and committed to their organizations. Developing professional competency and organizational commitment is vital, but not easy. …”
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451por Nagosa, Sara, Leesch, Friederike, Putin, Daria, Bhattacharya, Swarnabh, Altshuler, Anna, Serror, Laura, Amitai-Lange, Aya, Nasser, Waseem, Aberdam, Edith, Rouleau, Matthieu, Tattikota, Sudhir G., Poy, Matthew N., Aberdam, Daniel, Shalom-Feuerstein, RubyEnlace del recurso
Publicado 2017
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452“…A review of literature on this subject revealed the lack of scales designed for measuring professional commitment in nurses. The present study was designed to develop a scale to measure professional commitment in clinical nurses and examine its psychometric properties. …”
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455“…The use of conditional transgenic mouse models specifically targeting individual mTOR signalling components, together with selective inhibitors, have generated a significant body of research emphasising the critical roles played by mTOR, and individual mTOR complexes, in haemopoietic lineage commitment and development. This review will describe the profound role of mTOR in embryogenesis and haemopoiesis, underscoring the importance of mTORC1 at the early stages of haemopoietic cell development, through modulation of stem cell potentiation and self-renewal, and erythroid and B cell lineage commitment. …”
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457por Festuccia, Nicola, Halbritter, Florian, Corsinotti, Andrea, Gagliardi, Alessia, Colby, Douglas, Tomlinson, Simon R, Chambers, Ian“…Here, we purify ESCs with distinct TF expression levels from LIF/FCS cultures to uncover early events during commitment from naïve pluripotency. ESCs carrying fluorescent Nanog and Esrrb reporters show Esrrb downregulation only in Nanog(low) cells. …”
Publicado 2018
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458por Ng, Kenneth KH, Yui, Mary A, Mehta, Arnav, Siu, Sharmayne, Irwin, Blythe, Pease, Shirley, Hirose, Satoshi, Elowitz, Michael B, Rothenberg, Ellen V, Kueh, Hao Yuan“…Here, we studied the activation of Bcl11b, which controls T-cell fate commitment. To disentangle cis and trans effects, we generated mice where two Bcl11b copies are tagged with distinguishable fluorescent proteins. …”
Publicado 2018
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