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  1. 11721
    “…At 8 weeks after transplantation, immunohistochemical analysis showed that attenuated reactive gliosis did not affect neurogenesis or commitment towards glial lineage of the grafted NSPCs. …”
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    Attenuation of reactive gliosis in stroke-injured mouse brain does not affect neurogenesis from grafted human iPSC-derived neural progenitors
  2. 11722
    “…MAF overexpression and knockdown experiments shed some light into the role of MAF in PMF pathogenesis, by demonstrating that MAF favors the megakaryocyte and monocyte/macrophage commitment of HPCs and leads to the increased expression of proinflammatory and profibrotic mediators. …”
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    Involvement of MAF/SPP1 axis in the development of bone marrow fibrosis in PMF patients
  3. 11723
    “…Exosomes derived from hMSCs in various stages of osteogenic differentiation committed homotypic cells to differentiate towards osteogenic lineage, but only exosomes from late stages of osteogenic differentiation induced extracellular matrix mineralisation. …”
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    Mesenchymal stem cell-derived exosomes have altered microRNA profiles and induce osteogenic differentiation depending on the stage of differentiation
  4. 11724
    “…INTRODUCTION: The Council Directive 2013/59 Euratom has a clear commitment for keeping medical radiation exposure as low as reasonably achievable and demands a regular review and use of diagnostic reference levels. …”
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    Ultralow Dose MSCT Imaging in Dental Implantology
  5. 11725
    “…Bi-DOCS therefore highlight genes and pathways governing islet-lineage commitment, which can be exploited for differentiation protocol optimization, diabetes disease modeling, and therapeutic purposes.…”
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    Genes Associated with Pancreas Development and Function Maintain Open Chromatin in iPSCs Generated from Human Pancreatic Beta Cells
  6. 11726
    “…This analysis describes an innovative and successful approach to risk identification and mitigation in relation to the switch from trivalent to bivalent oral polio vaccine (OPV) in the 11 countries of the World Health Organization’s (WHO’s) South-East Asia Region (SEAR) in April 2016. The strong commitment of governments and immunization professionals to polio eradication and an exemplary partnership between the WHO, United Nations Children’s Fund (UNICEF), and other partners and stakeholders in the region and globally were significant contributors to the success of the OPV switch in the SEAR. …”
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    The Switch From Trivalent to Bivalent Oral Poliovirus Vaccine in the South-East Asia Region
  7. 11727
    “…RESULTS: HSWs’ work outcomes, including intent to stay, organizational citizenship behaviors, and performance, are directly and significantly related to their work attitudes, including job satisfaction, work engagement, and affective organizational commitment. These in turn are related to how HSWs perceive their work environments including their quality of work life (QWL), their perceptions of supervisor support, and their perceptions of workplace safety. …”
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    Relationships between work outcomes, work attitudes and work environments of health support workers in Ontario long-term care and home and community care settings
  8. 11728
    “…Implanted cells survived over a 10 day period in culture after transplantation and demonstrated commitment to a neural lineage. Our device provides a quick, effective, and aseptic method for the encapsulation of two different stem cell types (DPSCs and NSCs) within alginate-collagen microcapsules. …”
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    Microfluidic Encapsulation Supports Stem Cell Viability, Proliferation, and Neuronal Differentiation
  9. 11729
    “…However, the epigenetic mechanisms governing the lineage-specific commitment of BMSCs into adipocytes or osteoblasts are under investigation. …”
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    Romidepsin Promotes Osteogenic and Adipocytic Differentiation of Human Mesenchymal Stem Cells through Inhibition of Histondeacetylase Activity
  10. 11730
    “…CONCLUSION: We conclude that miRNA play an important role in megakaryocyte differentiation and may be used as targets to change the rate of differentiation and further our understanding of the biology of megakaryocyte commitment.…”
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    MicroRNA Microarray Profiling during Megakaryocyte Differentiation of Cord Blood CD133+ Hematopoietic Stem Cells
  11. 11731
    por Arensberg, Mary Beth
    Publicado 2018
    “…Healthy aging also requires a sustained commitment and action from country leaders to formulate evidence-based polices--like systematic nutrition screening and intervention—and healthcare workforce training and education that can strengthen and support an active aging population. …”
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    Population aging: opportunity for business expansion, an invitational paper presented at the Asia-Pacific Economic Cooperation (APEC) International Workshop on Adaptation to Population Aging Issues, July 17, 2017, Ha Noi, Viet Nam
  12. 11732
    “…We found that irradiated HSPCs, but not lineage-committed progenitors (CPs), undergo rapid ATM-dependent apoptosis, which is suppressed upon interaction with bone-marrow stroma cells. …”
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    Attenuated DNA damage responses and increased apoptosis characterize human hematopoietic stem cells exposed to irradiation
  13. 11733
    “…The petition process was a monumental effort that required collaboration and commitment by partners representing the affected population, manufacturers, scientists, and others. …”
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    Adding folic acid to corn Masa flour: Partnering to improve pregnancy outcomes and reduce health disparities()
  14. 11734
    “…Ablation of mTOR in myeloid cells also resulted in an increased number of eosinophil lineage-committed progenitors (Eops) in allergic mice. Collectively, our data uncovered the differential effects of mTOR in the regulation of eosinophil development, likely due to the distinct functions of mTOR complex 1 or 2, which thus exerts a pivotal implication in eosinophil-associated diseases.…”
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    mTOR complexes differentially orchestrates eosinophil development in allergy
  15. 11735
    “…CONCLUSION: The findings of the present investigations depicted a higher level of passion and commitment among the male and female respondents for the profession in spite of the fact that they do not have adequate time for their personal life. …”
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    An assessment of job satisfaction: A cross-sectional study among orthodontists of Saudi Arabia
  16. 11736
    “…The involvement and commitment of physicians, employment specialists, and employers, and employees capacity for self-care seem decisive for employment re-integration success. …”
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    Furthering the Evidence of the Effectiveness of Employment Strategies for People with Mental Disorders in Europe: A Systematic Review
  17. 11737
    “…In contrast, strong TCR signaling leading to TCR downregulation and induction of LAG3 expression in high TCR avidity clonotypes restrained CD4(+) T cell commitment and further differentiation. Finally, stunted Th1 differentiation, correlating with limited IL-2 availability in retroviral infection, provided permissive conditions for Tfh development, suggesting that Tfh differentiation is the default program of envelope-reactive CD4(+) T cells.…”
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    Correlates of Follicular Helper Bias in the CD4 T Cell Response to a Retroviral Antigen
  18. 11738
    “…Benefits included helpful information, developing commitment, physical fitness and social support; notably, weight was seldom mentioned. …”
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    Evaluation of an exercise programme for post‐bariatric surgery patients: views of participants
  19. 11739
    “…Bioinformatic analysis revealed that the hematopoietic stem cells exit from quiescence and commit to differentiation, which lead to hematopoietic stem cell exhaustion. …”
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    Setd2 regulates quiescence and differentiation of adult hematopoietic stem cells by restricting RNA polymerase II elongation
  20. 11740
    por Bar Shira, Enav, Friedman, Aharon
    Publicado 2018
    “…Thus, in the chicken, the intestinal epithelium, and particularly goblet cells, are committed to innate immune protection. The unique role of the goblet cell in chicken intestinal immunity, as well as the unique distribution of lysozyme-positive cells highlight alternative solutions of gut protection in the bird.…”
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    Innate immune functions of avian intestinal epithelial cells: Response to bacterial stimuli and localization of responding cells in the developing avian digestive tract
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