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  1. 11781
    por Manjula, M., Sudhir, Paulomi M.
    Publicado 2019
    “…A total of forty articles on mindfulness-based CT, metacognitive therapy, acceptance and commitment therapy, and danger ideation reduction therapy in the form of single-case studies, case series, open-label trials, two-group comparison studies, and randomized controlled studies were included. …”
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    New-wave behavioral therapies in obsessive-compulsive disorder: Moving toward integrated behavioral therapies
  2. 11782
    “…OBJECTIVES: The present study was committed to investigate the role of miR‐148a‐3p in HCC infected with hepatitis C virus (HCV) and the regulatory mechanism of miR‐148a‐3p/c‐Jun/MAPK signalling pathway. …”
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    Inhibition of miR‐148a‐3p resists hepatocellular carcinoma progress of hepatitis C virus infection through suppressing c‐Jun and MAPK pathway
  3. 11783
    “…In the present study, we have employed a high‐content high‐throughput screen to identify small molecules which inhibit the cellular process of Bax re‐distribution to the mitochondria following commitment of the cell to die. Screening of 6246 Generally Recognized As Safe compounds from four chemical libraries post‐induction of cisplatin‐mediated PCD resulted in the identification of 18 compounds which significantly reduced levels of Bax translocation. …”
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    Cell‐based high‐throughput screen for small molecule inhibitors of Bax translocation
  4. 11784
    “…AHR and GLIS1 control differentiation-induced genes and their overexpression can inhibit the lineage commitment of the multipotent bone marrow-derived ST2 cells.…”
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    Temporal enhancer profiling of parallel lineages identifies AHR and GLIS1 as regulators of mesenchymal multipotency
  5. 11785
    “…In Cuba, vaccination is free and it is integrated into primary health care, with universal access. The commitment and political will to the health of the population is conveyed through a comprehensive health system. …”
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    Experiencia cubana en inmunización, 1962–2016
  6. 11786
    “…The robustness of the historical data series and the commitment of the team implementing this initiative contributed to increase the trust of teams in the information generated. …”
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    Dezesseis anos de monitoramento em saúde na atenção primária em uma grande metrópole das Américas
  7. 11787
    por Crespo, Constanza Forascepi
    Publicado 2018
    “…Through a mixed health care model, Chile has met the commitment in the Declaration of Alma-Ata to the attainment of an “acceptable level of health for all the people,” achieving the best health and socioeconomic indicators in Latin America. …”
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    Chile: nuevos desafíos sanitarios e institucionales en un país en transición
  8. 11788
    “…OBJECTIVE: To analyze sources of fiscal space for the health sector in Honduras, in the context of sectoral reform, with a commitment to achieving the target of public expenditure on health equivalent to 6% of gross domestic product (GDP). …”
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    Espacio fiscal para salud en Honduras
  9. 11789
    “…INTRODUCTION: This study aims to obtain data on the prevalence and incidence of structural heart disease in a population setting and, to analyse and present those data on the application of spatial and machine learning methods that, although known to geography and statistics, need to become used for healthcare research and for political commitment to obtain resources and support effective public health programme implementation. …”
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    SALMANTICOR study. Rationale and design of a population-based study to identify structural heart disease abnormalities: a spatial and machine learning analysis
  10. 11790
    “…By being part of the European Institute of Innovation and Technology (EIT) Health public-private partnership, CLOSE is committed to the EIT “knowledge triangle” pursuing the integrated advancement of technology, education, and business creation. …”
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    Artificial Pancreas Systems for People With Type 2 Diabetes: Conception and Design of the European CLOSE Project
  11. 11791
    “…FST did not enhance osteogenic differentiation of MSCs, but increased committed osteoblast mineralization. In vivo, FST was loaded in an in situ gelling formulation made by alginate and recombinant collagen-based peptide microspheres and implanted in a rat calvarial defect model. …”
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    Follistatin Effects in Migration, Vascularization, and Osteogenesis in vitro and Bone Repair in vivo
  12. 11792
    “…NB arise from a transient population of embryonic cells, the neural crest (NC), and especially NC committed to the establishment of the sympatho-adrenal tissues. …”
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    Hijacking of Embryonic Programs by Neural Crest-Derived Neuroblastoma: From Physiological Migration to Metastatic Dissemination
  13. 11793
    “…The fear associated with lifelong commitment to insulin therapy once it is started, was also found statistically significant (p-value 0.001)particularly in subjects who have long duration of DM (>5 years). …”
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    Barriers to the early initiation of Insulin therapy among diabetic patients coming to diabetic clinics of tertiary care hospitals
  14. 11794
    “…Methylenetetrahydrofolate reductase (MTHFR) catalyzes the irreversible conversion of 5,10-methylene-tetrahydrofolate (THF) to 5-methyl-THF, thereby committing one-carbon units to the methionine cycle. …”
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    Regulation of folate and methionine metabolism by multisite phosphorylation of human methylenetetrahydrofolate reductase
  15. 11795
    “…In addition, AZA exerts a cytostatic effect that has a negative impact on the mitotic clonal process that is required for the terminal differentiation of the preadipocyte-committed cells.…”
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    The immunosuppressant drug azathioprine restrains adipogenesis of muscle Fibro/Adipogenic Progenitors from dystrophic mice by affecting AKT signaling
  16. 11796
    “…RESULTS: We showed that polysome-bound RNAs exhibit the cardiomyogenic commitment gene expression and that mesoderm-to-cardiac progenitor stages are strongly regulated. …”
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    Cardiomyogenic differentiation is fine-tuned by differential mRNA association with polysomes
  17. 11797
    “…Normal T-cell differentiation requires a complex regulatory network which supports a series of maturation steps, including lineage commitment, T-cell receptor (TCR) gene rearrangement, and thymic positive and negative selection. …”
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    A critical regulator of Bcl2 revealed by systematic transcript discovery of lncRNAs associated with T-cell differentiation
  18. 11798
    por He, Zhimin, Zhu, Xinyi, Shi, Zhen, Wu, Tao, Wu, Li
    Publicado 2019
    “…Features that distinguish DC progenitor cells from each differentiation stages, related signaling pathways and transcription factors that are crucial for DC lineage commitment have been well-elucidated in numerous studies. …”
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    Metabolic Regulation of Dendritic Cell Differentiation
  19. 11799
    “…Mechanistically, MAPK signaling pathways were activated after the CTP-CM treatment, and the inhibitors targeting MAPK were identified which weakened the effects of CTM-CM on the committed differentiation of hDPSCs. These findings could lead to the creation of stem cell therapies for dental regeneration.…”
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    The Conditioned Medium of Calcined Tooth Powder Promotes the Osteogenic and Odontogenic Differentiation of Human Dental Pulp Stem Cells via MAPK Signaling Pathways
  20. 11800
    “…By proposing this framework, the authors hope to improve equity in global health partnerships via improved access to meaningful and productive educational experiences, particularly for foreign medical graduates with commitment to using their new knowledge and training upon return to their home countries.…”
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    Reconfiguring a One-Way Street: A Position Paper on Why and How to Improve Equity in Global Physician Training
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