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13301por Pauly, Bernadette, Wallace, Bruce, Pagan, Flora, Phillips, Jack, Wilson, Mark, Hobbs, Heather, Connolly, Joann“…These impacts were achieved with few new resources highlighting the commitment of agencies and harm reduction workers, particularly those with lived experience, in achieving beneficial impacts. …”
Publicado 2020
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13302por Lin, Victor J. T., Hu, Jiangnan, Zolekar, Ashwini, Yan, Liang-Jun, Wang, Yu-Chieh“…UEC-derived hiPSC-developed COs that were initially committed to forebrain development showed cellular plasticity to transition between prosencephalic and rhombencephalic fates in vitro and in vivo, indicating their potential to develop into the cell components of various brain regions. …”
Publicado 2020
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13303por Moalla, Khadija Sonda, Damak, Mariem, Chakroun, Olfa, Farhat, Nouha, Sakka, Salma, Hdiji, Olfa, Kacem, Hanen Haj, Rekik, Noureddine, Mhiri, Chokri“…Poor prognostic factors were: male sex, consumption of tobacco, a history of stroke, low Glasgow score, high NIHSS, headaches, acute symptomatic epileptic seizures, Babinski’s sign, mydriasis, aphasia, combined deviation of the head and the eyes, high PAS, PAD and PAM, hyperthermia, hyperglycaemia, leukocytosis, high concentration of CRP, creatinine, urea and troponin T, haemorrhagic stroke, perilesional oedema, a mass effect, commitment, total middle cerebral artery topography of ischemia, early signs of ischemia, meningeal hemorrhage, ventricular flood, hydrocephalus, the recourse to respiratory support, to anti-edematous treatment and to antihypertensive therapy, hemorrhagic transformation, vascular epilepsy, infectious, metabolic complications, complications of bed sores. …”
Publicado 2020
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13304“…DNA double-strand breaks are repaired by end-joining or homologous recombination. A key-committing step of recombination is DNA end resection. …”
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13305por Richards, Laura A., Kumari, Ashu, Knezevic, Kathy, Thoms, Julie AI, von Jonquieres, Georg, Napier, Christine E., Ali, Zara, O’Brien, Rosemary, Marks-Bluth, Jonathon, Maritz, Michelle F., Pickett, Hilda A, Morris, Jonathan, Pimanda, John E., MacKenzie, Karen L.“…Here it is shown for the first time that the telomerase RNA-binding protein dyskerin (encoded by DKC1) is dramatically upregulated as human hematopoietic stem and progenitor cells commit to the erythroid lineage, driving an increase in telomerase activity in the presence of limiting amounts of TERT mRNA. …”
Publicado 2020
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13306por Richard, Magali, Decamps, Clémentine, Chuffart, Florent, Brambilla, Elisabeth, Rousseaux, Sophie, Khochbin, Saadi, Jost, Daniel“…Applying the method to lung cancer cohorts, we observed that deregulated genes in tumors exhibit a cancer-type-specific commitment towards up- or down-regulation. Based on the individual information of deregulation given by PenDA, we were able to define two new molecular histologies for lung adenocarcinoma cancers strongly correlated to survival. …”
Publicado 2020
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13307por García-Cerdán, José G., Schmid, Eva M., Takeuchi, Tomomi, McRae, Ian, McDonald, Kent L., Yordduangjun, Nichakarn, Hassan, Ahmed M., Grob, Patricia, Xu, C. Shan, Hess, Harald F., Fletcher, Daniel A., Nogales, Eva, Niyogi, Krishna K.“…The low carotenoid content resulted from impaired biosynthesis at a step prior to phytoene, the committed precursor to carotenoids. The CPSFL1 protein bound phytoene and β-carotene when expressed in Escherichia coli and phosphatidic acid in vitro. …”
Publicado 2020
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13308por Morales Pantoja, Itzy E., Smith, Matthew D., Rajbhandari, Labchan, Cheng, Linzhao, Gao, Yongxing, Mahairaki, Vasiliki, Venkatesan, Arun, Calabresi, Peter A., Fitzgerald, Kathryn C., Whartenby, Katharine A.“…Low-dose IFNγ was not toxic but led to an early upregulation of interferon response genes in OPCs followed by an apparent redirection in lineage commitment from OL to a neuron-like phenotype in a significant portion of the treated cells. …”
Publicado 2020
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13309“…Social comparison to peers who were perceived to be less committed to medicine, and to relatable role models, reassured participants that someone from their background could succeed in medicine. …”
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13310por Kachare, Swapnil D., Kapsalis, Christina, Yun, Angelica, Kachare, Milind D., Davis, Jared, Weeks, Dexter, Jhang, Joyce, Wilhelmi, Bradon J., Kasdan, Morton L.“…Peer student mentors can effectively lead the workshop and minimize the time commitment needed by surgical faculty. This can serve as a new direction in medical education and an avenue for further studies to analyze the longitudinal effects of the curriculum on career choice and success in surgical residency.…”
Publicado 2020
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13311por Henderson, Stuart, Wagner, Jenny L., Gosdin, Melissa M., Hoeft, Theresa J., Unützer, Jürgen, Rath, Laura, Hinton, Ladson“…Care Partners sites negotiated the complexity of their partnerships drawing upon three main strategies: adaptation (allowing for flexibility and rapid change); integration (providing opportunities for multi‐level partnerships within and across organisations) and cultivation (fostering a commitment to the partnership and its value). These strategies provided opportunities for Care Partners collaborators to work with the inherent complexity of partnering. …”
Publicado 2020
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13312por Zakiei, Ali, Khazaie, Habibolah, Reshadat, Soheyla, Rezaei, Mohsen, Komasi, Saeid“…To solve these problems, it is recommended third-wave therapies be used, especially acceptance and commitment therapy.…”
Publicado 2020
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13313por Adesoye, T., Davis, C.H., Del Calvo, H., Shaikh, A.F., Chegireddy, V., Chan, E.Y., Martinez, S., Pei, K.Y., Zheng, F., Tariq, N.“…Success may be achieved with commitment to constant needs assessment in the changing landscape of healthcare with the goal of producing a skilled surgical workforce for public service.…”
Publicado 2021
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13314“…A previous study among programme managers and other stakeholders at the national level has documented tardiness in committing to the integration of services. In this paper, we aimed at unravelling pertinent challenges that confront TB-HIV integrated service delivery. …”
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13315por Campbell, Carl H., Binder, Sue, King, Charles H., Knopp, Stefanie, Rollinson, David, Person, Bobbie, Webster, Bonnie, Allan, Fiona, Utzinger, Jürg, Ame, Shaali M., Ali, Said M., Kabole, Fatma, N’Goran, Eliézer K., Tediosi, Fabrizio, Salari, Paola, Ouattara, Mamadou, Diakité, Nana R., Hattendorf, Jan, S. Andros, Tamara, Kittur, Nupur, Colley, Daniel G.“…Although not encountered in these two studies, as prevalence and intensity decrease, political and community commitment to population-wide MDA may decrease. Because of this potential problem, SCORE developed and funded the T5 strategy implemented in Egypt, Kenya, and Tanzania. …”
Publicado 2020
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13316por Kurenkova, Anastasiia D., Medvedeva, Ekaterina V., Newton, Phillip T., Chagin, Andrei S.“…With very few exceptions, all adult tissues in mammals are maintained and can be renewed by stem cells that self-renew and generate the committed progeny required. These functions are regulated by a specific and in many ways unique microenvironment in stem cell niches. …”
Publicado 2020
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13317“…Research participants have typically been instructed to commit a mock crime and conceal critical information, whereas in real life, people freely choose whether or not to engage in antisocial behavior. …”
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13318por Meza, Rosemary D., Kiche, Sharon, Soi, Caroline, Khairuzzaman, Alya N., Nales, Cristian J. Rivera, Whetten, Kathryn, Wasonga, Augustine I., Amanya, Cyrilla, Dorsey, Shannon“…Common facilitators included participant and counselor resources, counselor commitment behaviors and communication efforts to encourage attendance. …”
Publicado 2020
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13319“…The disciplinary actions noted in the 988 nurse sexual‐misconduct–related licensure reports were more frequently serious than those noted in the 207,023 reports for other offenses committed by nurses (90.8% vs. 74.8%, respectively; p < 0.001). …”
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13320por Howard, Maxine, Roiser, Jonathan P., Gilbert, Sam J., Burgess, Paul W., Dayan, Peter, Serpell, Lucy“…Participants demonstrated impaired action inhibition when fasted; committing significantly more errors of commission during a food-related Affective Shifting Task. …”
Publicado 2020
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