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  1. 13921
    por Okubo, Tadashi, Hogan, Brigid LM
    Publicado 2004
    “…CONCLUSIONS: Our results show that hyperactive Wnt signaling in lung progenitors expressing a lung-specific gene can induce a dramatic switch in lineage commitment and the generation of intestinal cell types. …”
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    Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm
  2. 13922
    “…This would appear to be a good indicator that the healthcare sector may be boosted in the future by doctors who are wholeheartedly committed to the service of the communities with the greatest disease burden.…”
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    Choice of speciality amongst first-year medical students in the Nelson R. Mandela School of Medicine, University of KwaZulu-Natal
  3. 13923
    por Negi, Sandeep S., Brown, Patrick
    Publicado 2015
    “…Our results show that short exposure to CX-5461 followed by drug washout is sufficient to induce persistent G2 cell-cycle arrest and irreversible commitment to cell death, in spite of rRNA synthesis returning to normal within 24 hours of drug washout. …”
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    Transient rRNA synthesis inhibition with CX-5461 is sufficient to elicit growth arrest and cell death in acute lymphoblastic leukemia cells
  4. 13924
    “…BACKGROUND: The product of the educational nursing programs in Iran is training nurses who less have professional apprehension and commitment for participating in professional decisions. …”
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    Modification of Nursing Education for Upgrading Nurses’ Participation: A Thematic Analysis
  5. 13925
    “…The main themes emerging as barriers to screening were lack of time, staff turnover, inadequate finance, ignorance of a clear definition, poor commitment to screening, obligatory follow-up, risk of deterioration of the doctor-patient relationship, and insincerity on the part of the patient. …”
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    Barriers to Screening and Possibilities for Active Detection of Family Medicine Attendees Exposed to Intimate Partner Violence
  6. 13926
    “…Subjects who exhibit a stronger increase in phase alignment of low-frequency oscillatory activity in mPFC and STN before making a response have higher decision thresholds and commit fewer erroneous responses. Together, our results demonstrate that STN low-frequency oscillatory activity and corresponding mPFC-STN coupling are involved in determining how much evidence subjects accumulate before making a decision. …”
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    Neural Correlates of Decision Thresholds in the Human Subthalamic Nucleus
  7. 13927
    por Morain, Stephanie R., Kass, Nancy E.
    Publicado 2016
    “…CONCLUSION: To our knowledge, this is the first project to ask leaders from health care systems committed to ongoing learning about the ethical issues they have faced in this effort. …”
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    Ethics Issues Arising in the Transition to Learning Health Care Systems: Results from Interviews with Leaders from 25 Health Systems
  8. 13928
    “…BACKGROUND: Many neonatal deaths can be prevented globally through effective resuscitation. South Africa (SA) committed towards attaining the Millennium Development Goal 4 (MDG4) set by the World Health Organization (WHO). …”
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    Strategies to sustain a quality improvement initiative in neonatal resuscitation
  9. 13929
    “…The third main theme emerged as “dignifying and transcendental professional service” and consisted of two subthemes: “professional commitment to uphold patients’ rights” and “enlightened practice”. …”
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    Patients’ lived experiences regarding maintaining dignity
  10. 13930
    “…It also depends on the engagement of governments, academia, industry, healthcare providers, the general public, and the agricultural community, as well as international partners. Committing to combating antibiotic-resistant microbes does support patient care, economic growth, agriculture, and economic and national security.…”
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    Surveillance and Control of Antibiotic Resistance in the Mediterranean Region
  11. 13931
    “…The key molecular switch in the commitment of mesenchymal progenitors to osteoblast lineage is the transcription factor cbfa/runx2, which has multiple upstream regulators and a wide variety of targets. …”
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    Osteoblast Differentiation at a Glance
  12. 13932
    por Labonté, Ronald
    Publicado 2016
    “…But the acceleration of ecological crises and economic inequalities since then, in a more complex and multi-polar world, pose dramatically new challenges for those committed to the original vision of the Charter. Can the 2015 Sustainable Development Goals (SDGs), agreed to by all the world’s governments, offer a new advocacy and programmatic platform for a renewal of health promotion’s founding ethos? …”
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    Health Promotion in an Age of Normative Equity and Rampant Inequality
  13. 13933
    “…The positive feedback in Cdk1 activation creates a bistable switch that makes mitotic commitment irreversible [2, 3, 4]. Here, we surprisingly find that Cdk1 auto-activation is dispensable for irreversible, switch-like mitotic entry due to a second mechanism, whereby Cdk1:CycB inhibits its counteracting phosphatase (PP2A:B55). …”
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    Two Bistable Switches Govern M Phase Entry
  14. 13934
    por Olesen, Ole F., Ackermann, Marit
    Publicado 2017
    “…Average annual FP7 investment in NID research exceeded €24 million, triple that committed by the EU before the launch of FP7. FP7 NID projects involved research teams from 331 different institutions in 72 countries on six continents, underlining the increasingly global nature of European research activities. …”
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    Increasing European Support for Neglected Infectious Disease Research
  15. 13935
    “…Although the INDDEX Project activities are expected to improve the ability of researchers and policymakers in low-income countries to collect, process, and use dietary data, the global nutrition community is urged to commit further significant investments in order to adequately address the range and scope of challenges described in this paper.…”
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    Overcoming Dietary Assessment Challenges in Low-Income Countries: Technological Solutions Proposed by the International Dietary Data Expansion (INDDEX) Project
  16. 13936
    “…However, student participation in the design of marketing materials may increase the material's salience, while also improving children's commitment and attitudes towards healthy eating. The impact of student-led design of vegetable promotional materials on choice and consumption was investigated using 1614 observations of students' vegetable choice and plate waste in four public elementary schools in Kearney, Nebraska. …”
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    Impact of schoolchildren's involvement in the design process on the effectiveness of healthy food promotion materials()
  17. 13937
    Publicado 1990
    “…The ideal requirements include a small but committed multidisciplinary stroke care team, with an awareness of psychological problems that may occur after a stroke; a rehabilitation ward for patients in the recovery phase may also be of value, but this has not yet been fully assesssd. …”
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    Stroke: Towards Better Management: Summary and Recommendations of a Report of the Royal College of Physicians
  18. 13938
    “…Uniquely Japanese beliefs and values that do not rely on a commitment to any spiritual or religious affiliations or proprietary knowledge of traditional or biomedicine may be successfully exported from Japan to advance acupuncture education, research and practice in international contexts.…”
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    Beliefs and values in Japanese acupuncture: an ethnography of Japanese trained acupuncture practitioners in Japan
  19. 13939
    “…SIMPLE SUMMARY: The Human Continuum is a classroom exercise for secondary and tertiary students that offers a cooperative/cognitive learning strategy, requiring students to identify and commit to a position in response to a stimulus question. …”
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    The Use of a Virtual Online Debating Platform to Facilitate Student Discussion of Potentially Polarising Topics
  20. 13940
    “…However, additional important factors for implementation of salt iodization and maintenance of achievements include the salt industry’s structure and capacity to adequately fortify, and official commitment and capacity to enforce national legislation.…”
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    The legislative framework for salt iodization in Asia and the Pacific and its impact on programme implementation
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