“…Furthermore, the lack of PfcGlo2, but not PfGlo1, increased gametocyte commitment in the knockout lines. In summary, PfGlo1 and PfcGlo2 are dispensable during asexual blood-stage development while the loss of PfcGlo2 may induce the formation of transmissible gametocytes. …”
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“…Interestingly, in PSCs, the Wnt/β-catenin–TCF/LEF axis has several unrelated and sometimes opposite cellular functions such as self-renewal, stemness, lineage commitment and cell cycle regulation. In addition, tight control of the Wnt signaling pathway enhances reprogramming of somatic cells to induced pluripotency. …”
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“…A shift to a culture whereby evidence-based IPEP practices in community-AF will take time, and persistent commitment by all involved in the sport is important. …”
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“…BACKGROUND: In the 2010 Australian Federal Budget funding was committed to establish an early psychosis service system based on the EPPIC model of early intervention for psychosis that was developed in Melbourne, Australia. …”
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“…In conclusion, the CRSCI program approach and selected activities illustrate a way forward toward robust, targeted local preparedness and response that may serve as a useful example for public health departments in the United States and internationally, particularly at a time of uncertain commitment to climate change agreements at the national level. https://doi.org/10.1289/EHP1838…”
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“…Up to 40% of persons with alcoholism attempt suicide at some time and 7% end their lives by committing suicide. Risk factors include being male, older than 50 years of age, living alone, being unemployed, poor social support, interpersonal losses, continued drinking, consumption of a greater amount of alcohol when drinking, a recent alcohol binge, previous alcohol treatment, a family history of alcoholism, a history of comorbid substance abuse (especially cocaine), a major depressive episode, serious medical illness, suicidal communication, and prior suicidal behavior. …”
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“…These results suggested that both relapsed tumors of different cell lineages are derived from a common malignant clone, presumably a committed lymphoid stem cell. A unique translocation, t(2;14)(q37;q11.2), which may involve TCR δ/α gene complex, was observed in the second relapsed tumor and AST‐1 cells. …”
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“…At the restriction point (R-point), cells become irreversibly committed to the completion of the cell cycle independent of mitogen. …”
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“…CONCLUSION: This study highlights the need of survivors of sexual assault for integrated, patient-centred care, encompassing principles of good communication. Committed actions of all stakeholders are necessary to tackle negative perceptions that create barriers to follow-up care. …”
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“…The present study examined the effects of phloretin on the commitment of marrow stromal cells to adipocytes, using the mouse marrow stromal cell line ST2. …”
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“…OBJECTIVES: The Thai Ministry of Public Health is committed to reaching the United Nations’ goal of zero new HIV infections, zero AIDS-related deaths, and zero discrimination towards people living with HIV by 2030. …”
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“…Ninety-one percent of homicides of LEOs were committed with a firearm. CONCLUSIONS: This information is critical to help describe encounter situations faced by LEOs. …”
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“…Several quality dimensions were statistically significant for the employment profile: overall commitment to quality (p = 0.001); investigating patient incidents (p = 0.031); organisational learning following incidents (p < 0.001); communication around safety issues (p = 0.001); and team working around safety issues (p = 0.005). …”
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“…Students commented that it relieved some of the stress of the year-end examinations, and was generally motivating with regard to their work commitment. CONCLUSIONS: Being satisfied with how and what we assess in Histology, we are of the opinion that this reward system may contribute to engendering appropriate learning approaches (i.e. for understanding) in students. …”
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“…CONCLUSIONS: This study establishes a probable causative relationship between vascular structural abnormality and depression which may drive the individual to commit suicide.…”
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“…BACKGROUND: General practice recruitment is in difficulty in the UK as many experienced GPs retire or reduce their commitment. The numbers of junior doctors choosing to specialise in the discipline is also falling, leading to primary care workforce issues particularly in 'hard to serve' areas. …”
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“…Our results show that Samp1 is uniformly distributed at the nuclear periphery of normal human myotubes and committed myoblasts, but its anchorage at the nuclear poles is related to the presence of farnesylated prelamin A and it is disrupted by the loss of prelamin A farnesylation. …”
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“…Data were gathered from the official competition web page (www.acb.com) The variables analysed included rule modifications, the number of ball possessions, points scored, one, two and 3-point field goals made and attempted, total rebounds, defensive and offensive rebounds, assists, steals, turnovers, blocked shots, dunks and committed and received personal fouls, score differences, as well as one, two and 3-point field-goal percentages. …”
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“…OBJECTIVE: To share our jointly developed techniques to ensure the meaningful engagement and contribution of people with lived experience of the criminal justice system (PWLECJS) in research, trial science, intervention theory development and dissemination. METHODS: Commitment to adequate financial resources, appropriate staff skills and adequate time were combined with previous learning. …”
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“…New approaches to overcome this, such as forming clear “asks” to government and committing industry to “pledges” on reformulation were suggested. …”
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