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  1. 14221
    “…We favor the concept that γ(c)-dependent receptors are required for the maintenance of TCR-γ/δ cells and contribute to the completion of TCR-γ rearrangements primarily by promoting survival of cells committed to the TCR-γ/δ lineage.…”
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    The Common Cytokine Receptor γ Chain Controls Survival of γ/δ T Cells
  2. 14222
    “…In addition, our results strongly suggest the possibility of establishing useful cell lines committed to specific lineages other than hematopoietic progenitors from human ES cells.…”
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    Establishment of Mouse Embryonic Stem Cell-Derived Erythroid Progenitor Cell Lines Able to Produce Functional Red Blood Cells
  3. 14223
    “…BACKGROUND: In order to reduce maternal mortality, the Indian government has increased its commitment to institutional deliveries. We assess the determinants of home, private and public sector utilization for a delivery in a Western state. …”
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    Where to deliver? Analysis of choice of delivery location from a national survey in India
  4. 14224
    “…As secreted proteins could regulate the balance between both lineages, we aimed at characterizing the secretome of human multipotent adipose-derived stem cell (hMADS) at an early step of commitment to adipocytes and osteoblasts. RESULTS: A proteomic approach, using mono-dimensional electrophoresis and tandem mass spectrometry, allowed us to identify a total of 73 proteins at day 0 and day 3 of adipocyte and osteoblast differentiation. …”
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    Characterization of human mesenchymal stem cell secretome at early steps of adipocyte and osteoblast differentiation
  5. 14225
    “…Almost one third (30.8%) described symptoms of depression and 37.0% reported having tried to commit suicide or seriously thought about it. 77.8% of the former patients were still in outpatient treatment. …”
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    The psychopathological and psychosocial outcome of early-onset schizophrenia: Preliminary data of a 13-year follow-up
  6. 14226
    por Brown, Amanda C, Parish, Tanya
    Publicado 2008
    “…Fosmidomycin is a phosphonic antibiotic which inhibits 1-deoxy-D-xylulose 5-phosphate reductoisomerase (Dxr), the first committed step of the non-mevalonate pathway of isoprenoid biosynthesis. …”
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    Dxr is essential in Mycobacterium tuberculosis and fosmidomycin resistance is due to a lack of uptake
  7. 14227
    “…Although Bcl-XL and Bax are structurally similar, activated Bax forms large oligomers that permeabilize the outer mitochondrial membrane, thereby committing cells to apoptosis, whereas Bcl-XL inhibits this process. …”
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    Bcl-XL Inhibits Membrane Permeabilization by Competing with Bax
  8. 14228
    “…BACKGROUND: Job satisfaction is an important component of nurses' lives that can impact on patient safety, productivity and performance, quality of care, retention and turnover, commitment to the organisation and the profession. Little is known about job satisfaction in early career and how it varies for different groups of nurses. …”
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    Job satisfaction trends during nurses' early career
  9. 14229
    “…OBJECTIVE—Cytosolic phosphoenolpyruvate carboxykinase (PEPCK-C; encoded by Pck1) catalyzes the first committed step in gluconeogenesis. Extensive evidence demonstrates a direct correlation between PEPCK-C activity and glycemia control. …”
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    Pck1 Gene Silencing in the Liver Improves Glycemia Control, Insulin Sensitivity, and Dyslipidemia in db/db Mice
  10. 14230
    por Adano, Ummuro
    Publicado 2008
    “…It is essential to establish partnerships and foster commitment and collaboration to create needed change in human resource management (HRM). …”
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    The health worker recruitment and deployment process in Kenya: an emergency hiring program
  11. 14231
    “…With these assumptions, the results of simulations successfully describe the biphasic behavior as well as lineage commitment. The model also predicts that reprogramming the network from a differentiated state, in particular the endoderm state, into a stem cell state, is best achieved by over-expressing Nanog, rather than by suppression of differentiation genes such as Gata-6. …”
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    A Computational Model for Understanding Stem Cell, Trophectoderm and Endoderm Lineage Determination
  12. 14232
    “…Female and male responders differed in the domains professional commitment, resistance to stress and emotional well-being. …”
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    Psychosocial health risk factors and resources of medical students and physicians: a cross-sectional study
  13. 14233
    “…In view of a growing global commitment to control soil-transmitted helminthiasis, there is a need to elucidate the effect of repeated stool sampling and the use of different diagnostic methods in areas targeted for preventive chemotherapy that are characterized by low-infection intensities. …”
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    Diagnosis of Soil-Transmitted Helminths in the Era of Preventive Chemotherapy: Effect of Multiple Stool Sampling and Use of Different Diagnostic Techniques
  14. 14234
    “…This approach will not only enhance drug discovery process, but also save time and resources committed.…”
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    Classification of drug molecules considering their IC(50 )values using mixed-integer linear programming based hyper-boxes method
  15. 14235
    “…CDEMS rates of care were compared with those reported by other data sources, but no consistent pattern of similarities or differences emerged. CONCLUSION: With committed staff time, provider support, and resources, data from clinical information systems like CDEMS can be combined to address a deficiency in state-level diabetes surveillance and evaluation systems — specifically, the inability to capture clinical biometric values to measure intermediate health outcomes. …”
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    Exploring the Feasibility of Combining Chronic Disease Patient Registry Data to Monitor the Status of Diabetes Care
  16. 14236
    “…Furthermore, B cell differentiation is impaired at an early stage in the bone marrow: a first block is observed during B cell commitment and a second differentiation block is seen at the large preB2 cell stage. …”
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    Enforced Expression of the Transcriptional Coactivator OBF1 Impairs B Cell Differentiation at the Earliest Stage of Development
  17. 14237
    “…FINDINGS: WB cells were grown in high glucose medium containing Pdx-1 or Pdx-1-VP16 recombinant proteins for two weeks. β-like cell commitment was analysed by RT-PCR of pancreatic endocrine genes. …”
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    Pdx-1 or Pdx-1-VP16 protein transduction induces β-cell gene expression in liver-stem WB cells
  18. 14238
    “…S-type cells appear irreversibly committed to a glial lineage fate.…”
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    Comprehensive characterization of neuroblastoma cell line subtypes reveals bilineage potential similar to neural crest stem cells
  19. 14239
    “…Given the synaptic commitment inherent in LTP consolidation, we considered that HFS-evoked expression of Arc could be used to timemap the functional integration of newborn DGCs. …”
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    Selective Survival and Maturation of Adult-Born Dentate Granule Cells Expressing the Immediate Early Gene Arc/Arg3.1
  20. 14240
    por Long, Andrew F
    Publicado 2009
    “…CONCLUSION: Supporting individuals to take control of their self-care requires advice-giving within a supportive treatment context and practitioner relationship, with clients who are open to change and committed to maintaining their health. CAM modalities may have an important role to play in this endeavour.…”
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    The potential of complementary and alternative medicine in promoting well-being and critical health literacy: a prospective, observational study of shiatsu
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