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14241por Cultrera, Concetta“…INTRODUCTION: The announcement of the Commission strategy for supporting the quality of social services of general interest (SSGI) across the European Union in the Communication on “services of general interest, including social services of general interest: a new European commitment”. THE REASONS FOR A QUALITY FRAMEWORK: First, when dealing with a variety of providers, public authorities need to clearly define the services they are delegating and thus the quality they expect. …”
Publicado 2009
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14242“…Oral health promotion initiatives among immigrants should be based upon optimal descriptive data in order to accomplish the inherent social commitment to these diverse populations.…”
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14243“…These data, together with previous studies, suggest that the LIN28-expressing undifferentiated spermatogonia exist as two subpopulations: Ngn3-GFP-negative (high stem cell potential) and Ngn3-GFP-positive (high differentiation commitment). Furthermore, Ngn3-GFP-negative cells are found in chains of Ngn3-GFP-positive spermatogonia, suggesting that cells in the A(al )spermatogonia could revert to a more primitive state.…”
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14244“…In this review, we analyze the effects of drugs such as (a) statins, which act on the mevalonate pathway by inhibiting HMG-CoA reductase, (b) bisphosphonates, which interfere with the isoprenoid pathway in the step catalyzed by farnesyl diphosphate synthase, (c) zaragozic acids and quinuclidines, inhibitors of squalene synthase (SQS), which catalyzes the first committed step in sterol biosynthesis, (d) allylamines, inhibitors of squalene epoxidase, (e) azoles, which inhibit C14α-demethylase, and (f) azasterols, which inhibit Δ(24(25))-sterol methyltransferase (SMT). …”
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14245por Sviderskaya, Elena V., Easty, David J., Lawrence, Mark A., Sánchez, Daniel P., Negulyaev, Yuri A., Patel, Ricken H., Anand, Praveen, Korchev, Yuri E., Bennett, Dorothy C.“…Neural-crest-related stem cells have been reported previously in postnatal skin: committed melanocytic stem cells in the hair follicle, and pluripotent cell types from the hair follicle and papilla that can produce various sets of lineages. …”
Publicado 2009
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14246“…Additionally, students perceived the tutorial as helpful in preparing for exam questions and reviewing the course material. The time commitment for use of the case-based tutorial appears to be justified.…”
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14247“…Besides adapting the function to the local situation, some general aspects for success can be indicated: the ethnic background of the HC advisor should correspond to the main ethnic minority groups in the district, HC advisors need to conduct outreach work, there must be a well-organized back office to refer clients to, and there needs to be enough commitment among professionals of local health and welfare services.…”
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14248por Debeb, Bisrat G., Galat, Vasiliy, Epple-Farmer, Jessica, Iannaccone, Steve, Woodward, Wendy A., Bader, Michael, Iannaccone, Philip, Binas, Bert“…Recent findings suggest that the committed ExEn precursor is present already in the embryonic Inner Cell Mass (ICM) as a group of cells that intermingles with the closely related epiblast precursor. …”
Publicado 2009
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14249por Harris, Sam, Kaplan, Jonas T., Curiel, Ashley, Bookheimer, Susan Y., Iacoboni, Marco, Cohen, Mark S.“…METHODOLOGY/PRINCIPAL FINDINGS: We used functional magnetic resonance imaging (fMRI) to measure signal changes in the brains of thirty subjects—fifteen committed Christians and fifteen nonbelievers—as they evaluated the truth and falsity of religious and nonreligious propositions. …”
Publicado 2009
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14250por Mann, Francis M., Prisic, Sladjana, Hu, Huayou, Xu, Meimei, Coates, Robert M., Peters, Reuben J.“…Here, we present characterization of the class II diterpene cyclase that catalyzes the committed step in edaxadiene biosynthesis, i.e. the previously identified halimadienyl-diphosphate synthase (HPS; EC 5.5.1.16). …”
Publicado 2009
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14251por Meng, Ping Hong, Raynaud, Cécile, Tcherkez, Guillaume, Blanchet, Sophie, Massoud, Kamal, Domenichini, Séverine, Henry, Yves, Soubigou-Taconnat, Ludivine, Lelarge-Trouverie, Caroline, Saindrenan, Patrick, Renou, Jean Pierre, Bergounioux, Catherine“…A yeast two-hybrid screen using ATXR5 as bait captured AtIPS1, an enzyme which catalyses the committed step of myo-inositol (MI) biosynthesis. atips1 mutants form spontaneous lesions on leaves, raising the possibility that MI metabolism may play a role in the control of PCD in plants. …”
Publicado 2009
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14252“…This suggests that EGF withdrawal is the dominant feature of these differentiation protocols and that exposure to either serum or CNTF is insufficient to irreversibly commit a cultured RPC population to terminal differentiation unless accompanied by concomitant cessation of mitogenic stimulation.…”
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14253por Remmen, Roy, Seuntjens, Luc, Paulus, Dominique, Pestiaux, Dominique, Knops, Klaus, Bruel, Ann Van den“…It proved attractive to participants, but it can be augmented by coaching of participants in more than a one-off project to identify and achieve targets for quality improvement. In the absence of commitment of the government, a network of universities and one scientific organisation will offer EPA as a service to training practices.…”
Publicado 2009
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14254por Marengo, Eliana B., Commodaro, Alessandra Gonçalves, Peron, Jean Pierre S., de Moraes, Luciana V., Portaro, Fernanda C. V., Belfort, Rubens, Rizzo, Luiz Vicente, Sant'Anna, Osvaldo Augusto“…Our data indicate that rHsp65 is one of the managers with a significant impact over the immune response during autoimmunity, skewing it to a pathogenic state, promoting both Th1 and Th17 commitment. It seems comprehensible that the specificity and primary function of Hsp60 molecules can be considered as a potential pathogenic factor acting as a whistleblower announcing chronic-inflammatory diseases progression.…”
Publicado 2009
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14255“…CONCLUSION: Difference in intronic enhancers supporting 5' and 3' splice sites suggests an independent splicing commitment for neighboring exons. Increased evolutionary conservation for ISEs/ISSs within intronic flanks and effect of modulation of predicted elements on splicing suggest functional significance of found elements in splicing regulation. …”
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14256por Rossi, Carlo A., Pozzobon, Michela, Ditadi, Andrea, Archacka, Karolina, Gastaldello, Annalisa, Sanna, Marta, Franzin, Chiara, Malerba, Alberto, Milan, Gabriella, Cananzi, Mara, Schiaffino, Stefano, Campanella, Michelangelo, Vettor, Roberto, De Coppi, Paolo“…SCs may therefore be comprised of two distinct, though not irreversibly committed, populations of cells distinguishable for prominent differences in basal biological features such as proliferation, metabolism and differentiation. …”
Publicado 2010
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14257por Kanamoto, Takashi, Mizuhashi, Koji, Terada, Koji, Minami, Takashi, Yoshikawa, Hideki, Furukawa, Takahisa“…Several studies have shown that cell fate commitment within the osteoblast lineage requires sequential, stage-specific signaling to promote osteoblastic differentiation programs. …”
Publicado 2009
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14258“…BACKGROUND: Galactokinase catalyses the first committed step of galactose catabolism in which the sugar is phosphorylated at the expense of MgATP. …”
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14259por Polinder, Suzanne, Haagsma, Juanita A, Toet, Hidde, Brugmans, Marco JP, van Beeck, Ed F“…BACKGROUND: Injury is the major cause of death and suffering among children and adolescents, but awareness of the problem and political commitment for preventive actions remain unacceptably low. …”
Publicado 2010
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14260Suicide attempt in a rural area of Vietnam: Incidence, methods used and access to mental health carepor Nguyen, Tuan V, Dalman, Christina, Le, Thien C, Nguyen, Thiem V, Tran, Nghi V, Allebeck, Peter“…RESULTS: The yearly incidence was 10.2 per 100000 person-years, 10.6 per 100000 in males and 9.8 per 100000 in females. 99% of cases committed suicide attempt by poisoning, 62.6% by pesticides and 36.3% by pharmaceutical drugs. 34.3% reported having been in contact with somatic care and 13.2% had received mental health care. …”
Publicado 2010
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