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14281“…The course had a high level of commitment by teachers, included a valid and reliable final examination, and valid evaluation questionnaires that provided relevant information to assess curriculum function. …”
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14282“…BACKGROUND: The level of funding provides a good proxy for the level of commitment or prioritisation given to a particular issue. …”
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14283“…AIM: The objective of this study is to analyze the commitment to a more health-promoting health service and to illuminate important barriers for having a health-promoting role in daily practice, among Swedish health care professionals. …”
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14284por Mercer, Luke, Bowling, Tana, Perales, Joe, Freeman, Jennifer, Nguyen, Tien, Bacchi, Cyrus, Yarlett, Nigel, Don, Robert, Jacobs, Robert, Nare, Bakela“…Pulse incubation of T. brucei with SCYX-5070 demonstrates that a short period of exposure (10–12 hrs) is required to produce irreversible effects on survival or commit the parasites to death. SCYX-5070 cured an acute trypanosomiasis infection in mice without exhibiting signs of compound related acute or chronic toxicity. …”
Publicado 2011
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14285por Hewitt, Kyle J., Shamis, Yulia, Hayman, Ryan B., Margvelashvili, Mariam, Dong, Shumin, Carlson, Mark W., Garlick, Jonathan A.“…DNA methylation analysis of promoter regions associated with extracellular matrix (ECM)-production (COL1A1) by iPS- and hESC-derived fibroblasts and fibroblast lineage commitment (PDGFRβ), revealed promoter demethylation linked to their expression, and patterns of transcription and methylation of genes related to the functional properties of mature stromal cells were seen in both hiPS- and hES-derived fibroblasts. iPDK cells also showed functional properties analogous to those of hES-derived and mature fibroblasts, as seen by their capacity to direct the morphogenesis of engineered human skin equivalents. …”
Publicado 2011
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14286por Köksal, Mustafa, Jin, Yinghua, Coates, Robert M., Croteau, Rodney, Christianson, David W.“…A particularly eminent member of this family is the polycyclic diterpenoid Taxol (paclitaxel), which promotes tubulin polymerization1 and exhibits remarkable efficacy in cancer chemotherapy2. The first committed step of Taxol biosynthesis in the Pacific yew (Taxus brevifolia)3 is the cyclization of the linear isoprenoid substrate geranylgeranyl diphosphate (GGPP) to form taxa-4(5),11(12)diene4, which is catalyzed by taxadiene synthase5. …”
Publicado 2010
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14287por Davidoff, Frank“…Providing clinical care is above all a service; in that sense, the medical profession aspires to Aristotelian phronesis, or prudence—being ‘capable of action with regard to things that are good and bad for man.’ This intense commitment to service encourages healthcare providers to gravitate towards one or another epistemology as their preferred moral pathway to better care. …”
Publicado 2011
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14288“…In investigating the basis for this, we find DNA repair foci do not disassemble in ulp2 cells during recovery from the replication fork-blocking drug methyl methanesulfonate (MMS), corresponding with an accumulation of X-shaped recombination intermediates. ulp2 cells satisfy the DNA damage checkpoint during MMS recovery and commit to chromosome segregation with similar kinetics to wild-type cells. …”
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14289por Onoue, Noriyuki, Yamashita, Yui, Nagao, Nobuhiro, Goto, Derek B., Onouchi, Hitoshi, Naito, Satoshi“…Expression of the Arabidopsis CGS1 gene, encoding the first committed enzyme of methionine biosynthesis, is feedback-regulated in response to S-adenosyl-l-methionine (AdoMet) at the mRNA level. …”
Publicado 2011
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14290por Suzuki, Keiji, Mitsutake, Norisato, Saenko, Vladimir, Suzuki, Masatoshi, Matsuse, Michiko, Ohtsuru, Akira, Kumagai, Atsushi, Uga, Tatsuya, Yano, Hiroshi, Nagayama, Yuji, Yamashita, Shunichi“…These data suggest that those cells are derived from thyroid follicular cells or at least thyroid-committed cells. The SAGM-grown cells did not express any thyroid-specific genes. …”
Publicado 2011
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14291por Mulholland, Celene B., Aranda, Guzmán, Arredondo, Luis Angel, Calgua, Erwin, Contreras, Fernando, Espinoza, Dulce Maria, Gonzalez, Juan Bosco, Hoil, Jose A., Komolafe, Edward, Lazareff, Jorge A., Liu, Yunhui, Soto-Mancilla, Juan Luis, Mannucci, Graciela, Nan, Bao, Portillo, Santiago, Zhao, Hongyu“…METHODS: Twelve institutions in 7 countries committed to participating in the International Tethered Cord Partnership. …”
Publicado 2011
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14292“….%) are either disabled or in a very poor health condition, 40.9% are in extreme economic stress and only 10.6% remarried. 1 widow committed suicide and 3 attempted suicide. A total of 178 persons (male 82, female 96) attended the community mental health clinics. …”
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14293“…Intracellular Ca(2+) concentration ([Ca(2+)](i)) was monitored simultaneously to verify the cell commitment in the activation process. [Ca(2+)](i) increased a few tens of seconds after the beginning of the pushing phase although no strong correlation appeared between the two events. …”
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14294“…This situation presents medical radiation practitioners with opportunities for involvement, collaboration or leadership in research depending on their level of commitment and their ability to learn. Medical radiation practitioners already possess a large portion of the understanding, knowledge and skills necessary for involvement in MRI development and molecular imaging. …”
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14295“…Thus the Hoxb1 patterning activity includes the regulation of the cellular response to retinoic acid and the delay of the expression of genes that commit cells to neural differentiation. The results of this study show that ES neural differentiation and inducible Hox gene expression can be used as a sensitive model system to systematically identify Hox novel target genes, delineate their interactions with signaling pathways in dictating cell fate and define the extent of functional overlap among different Hox genes.…”
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14296por Al-Rubaish, Abdullah M., Rahim, Sheikh Idris A., Abumadini, Mahdi S., Wosornu, Lade“…These factors, in descending order of eigenvalue, were labeled “Authority”, “Supervision”, “Policies and Facilities”, “My Work Itself”, “Interpersonal Relationships”, “Commitment”, “Salary” and “Workload”. Cronbach's-α ranged from 0.90 in Supervision to 0.63 in Salary and Workload. …”
Publicado 2011
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14297por Bouché, Philippe, Douglas-Hamilton, Iain, Wittemyer, George, Nianogo, Aimé J., Doucet, Jean-Louis, Lejeune, Philippe, Vermeulen, Cédric“…Specific corridors designed to reduce the isolation of the surveyed populations are proposed. The strong commitment of governments, effective law enforcement to control the illegal ivory trade and the involvement of local communities and private partners are all critical to securing the future of elephants inhabiting Africa's northern savannas.…”
Publicado 2011
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14298por Dettman, E.J., Simko, Stephen J., Ayanga, Bernard, Carofino, Brandi, Margolin, Judith, Morse, Herbert C., Justice, Monica J.“…Microarray gene expression analysis of expanded CLP-like cells prior to the onset of leukemia demonstrated upregulation of genes involved in pluripotency, tumor initiation, early B-lineage commitment, Wnt/Ras signaling, and the epithelial-to-mesenchymal transition. …”
Publicado 2011
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14299por Milman Krentsis, Irit, Sela, Ilan, Eiges, Rachel, Blanchard, Véronique, Berger, Markus, Becker Cohen, Michal, Mitrani-Rosenbaum, Stella“…Furthermore very rare skeletal muscle committed cells were detected in the GNE KO ES cultures at any stage of differentiation, as assessed by analysis of the expression of either Pax7, MyoD and MyHC markers. …”
Publicado 2011
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14300por Regvar, Marjana, Eichert, Diane, Kaulich, Burkhard, Gianoncelli, Alessandra, Pongrac, Paula, Vogel-Mikuš, Katarina, Kreft, Ivan“…Mature developed seeds are physiologically and biochemically committed to store nutrients, principally as starch, protein, oils, and minerals. …”
Publicado 2011
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