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15861por Degenhardt, Louisa, Day, Carolyn, Hall, Wayne, Conroy, Elizabeth, Gilmour, Stuart“…Other States and territories that also experienced a heroin shortage but did not show any increases in cocaine use did not report any increase in violent crimes. The violent crimes committed did not involve guns, most likely because of its stringent gun laws, in contrast to the experience of American cities that have experienced high rates of cocaine use and violent crime.…”
Publicado 2005
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15862por Pompili, Maurizio, Amador, Xavier F, Girardi, Paolo, Harkavy-Friedman, Jill, Harrow, Martin, Kaplan, Kalman, Krausz, Michael, Lester, David, Meltzer, Herbert Y, Modestin, Jiri, Montross, Lori P, Bo Mortensen, Preben, Munk-Jørgensen, Povl, Nielsen, Jimmi, Nordentoft, Merete, Saarinen, Pirjo Irmeli, Zisook, Sidney, Wilson, Scott T, Tatarelli, Roberto“…There is almost total agreement that the schizophrenic patient who is more likely to commit suicide is young, male, white and never married, with good premorbid function, post-psychotic depression and a history of substance abuse and suicide attempts. …”
Publicado 2007
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15863por Xin, Li, Zhou, Guo-Ling, Song, Wei, Wu, Xue-Song, Wei, Gong-Hong, Hao, De-Long, Lv, Xiang, Liu, De-Pei, Liang, Chih-Chuan“…Higher eukaryotes have evolved elegant mechanisms by which committed gene-expression states are transmitted through numerous cell divisions. …”
Publicado 2007
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15864por Lodoen, Melissa, Ogasawara, Kouetsu, Hamerman, Jessica A., Arase, Hisashi, Houchins, Jeffrey P., Mocarski, Edward S., Lanier, Lewis L.“…Although CMV encodes several gene products committed to evasion of adaptive immunity, viral modulation of NK cell activity is only beginning to be appreciated. …”
Publicado 2003
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15865por Street, Annette F, Swift, Kathleen, Annells, Merilyn, Woodruff, Roger, Gliddon, Terry, Oakley, Anne, Ottman, Goetz“…RESULTS: Involving users in the identification of content and links for a palliative care website is time-consuming and requires initial resources, strong networking skills and commitment. However, user participation provided crucial information that led to the widened the scope of the website audience and guided the development and testing of the website. …”
Publicado 2007
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15866por van Oostrom, Sandra H, Anema, Johannes R, Terluin, Berend, de Vet, Henrica CW, Knol, Dirk L, van Mechelen, Willem“…The workplace intervention is a stepwise approach that aims to reach consensus about a return-to-work plan by active participation and strong commitment of both the sick-listed employee and the supervisor. …”
Publicado 2008
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15867por Lu, Shi-Jiang, Hipp, Jennifer A, Feng, Qiang, Hipp, Jason D, Lanza, Robert, Atala, Anthony“…Most differentiation protocols use a multi-stage approach that induces commitment along a particular lineage. Therefore, each stage represents a more mature and less heterogeneous phenotype. …”
Publicado 2007
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15868por Malik, Meghna R., Wang, Feng, Dirpaul, Joan M., Zhou, Ning, Hammerlindl, Joe, Keller, Wilf, Abrams, Suzanne R., Ferrie, Alison M. R., Krochko, Joan E.“…Expression analysis of marker genes for embryogenesis in Westar and the derived DH-2 line, using real-time reverse transcription-PCR, revealed that the timely expression of embryogenesis-related genes such as LEAFY COTYLEDON1 (LEC1), LEC2, ABSCISIC ACID INSENSITIVE3, and BABY BOOM1, and an accompanying down-regulation of pollen-related transcripts, were associated with commitment to embryo development in Brassica microspores. …”
Publicado 2008
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15869por Bradley, Elizabeth H, Nallamothu, Brahmajee K, Stern, Amy F, Byrd, Jason R, Cherlin, Emily J, Wang, Yongfei, Yuan, Christina, Nembhard, Ingrid, Brush, John E, Krumholz, Harlan M“…The Door-to-Balloon (D2B) Alliance is a collaborative effort of more than 900 hospitals committed to implementing a set of evidence-based strategies for reducing D2B time. …”
Publicado 2008
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15870por Chène, Patrick, Rudloff, Joëlle, Schoepfer, Joseph, Furet, Pascal, Meier, Peter, Qian, Zhiyan, Schlaeppi, Jean-Marc, Schmitz, Rita, Radimerski, Thomas“…Thus, interfering with ATPase function with low molecular weight inhibitors that target the nucleotide binding pocket should profoundly affect cells that are committed to undergo mitosis. RESULTS: Here we describe the discovery and characterization of a novel purine diamine analogue as a potent ATP-competitive catalytic inhibitor of topoisomerase II. …”
Publicado 2009
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15871por Shipman, Cathy, Gysels, Marjolein, White, Patrick, Worth, Allison, Murray, Scott A, Barclay, Stephen, Forrest, Sarah, Shepherd, Jonathan, Dale, Jeremy, Dewar, Steve, Peters, Marilyn, White, Suzanne, Richardson, Alison, Lorenz, Karl, Koffman, Jonathan, Higginson, Irene J“…A greater evidence base is needed to define models of good practice together with a commitment to provide education and training and adequate resources for service provision. …”
Publicado 2008
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15872por Sanchez, Alvaro, Grandes, Gonzalo, Cortada, Josep M, Pombo, Haizea, Balague, Laura, Calderon, Carlos“…DISCUSSION: There are four necessary factors for the outcome to be successful and result in important changes: (1) the commitment of professional and community partners who are involved; (2) their competence for change; (3) the active cooperation and participation of the interdisciplinary partners involved throughout the process of change; and (4) the availability of resources necessary to facilitate the change.…”
Publicado 2009
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15873por Hart-Kerkhoffs, Lisette 't A, Doreleijers, Theo AH, Jansen, Lucres MC, van Wijk, Anton PH, Bullens, Ruud AR“…Although one third of the juveniles had already committed one or more sex offenses prior to the index offense, at follow up (mean follow up period: 36 months SD 18 months) almost no sexual recidivism was found (0.6% of the entire sample). …”
Publicado 2009
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15874por Marks, M. David, Tian, Li, Wenger, Jonathan P., Omburo, Stephanie N., Soto-Fuentes, Wilfredo, He, Ji, Gang, David R., Weiblen, George D., Dixon, Richard A.“…Three candidates for the polyketide synthase (PKS) gene responsible for the first committed step in the pathway to THCA were characterized in more detail. …”
Publicado 2009
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15875“…METHODS: The official documents by the most representative health organisations committed to the definition of policies and guidelines for palliative and end-of-life care had been considered. …”
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15876por Medina, Reinhold J, O'Neill, Christina L, Sweeney, Mark, Guduric-Fuchs, Jasenka, Gardiner, Tom A, Simpson, David A, Stitt, Alan W“…CONCLUSIONS: This study provides evidence that eEPCs are haematopoietic cells with a molecular phenotype linked to monocytes; whereas OECs exhibit commitment to the endothelial lineage. These findings indicate that OECs might be an attractive cell candidate for inducing therapeutic angiogenesis, while eEPC should be used with caution because of their monocytic nature.…”
Publicado 2010
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15877por Hather, Gregory J., Haynes, Winston, Higdon, Roger, Kolker, Natali, Stewart, Elizabeth A., Arzberger, Peter, Chain, Patrick, Field, Dawn, Franza, B. Robert, Lin, Biaoyang, Meyer, Folker, Ozdemir, Vural, Smith, Charles V., van Belle, Gerald, Wooley, John, Kolker, Eugene“…To gauge the current commitment to scientific research in the United States of America (US), we compared federal research funding (FRF) with the US gross domestic product (GDP) and industry research spending during the past six decades. …”
Publicado 2010
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15878por Brooker, Simon, Okello, George, Njagi, Kiambo, Dubeck, Margaret M, Halliday, Katherine E, Inyega, Hellen, Jukes, Matthew CH“…DISCUSSION: Across Africa, governments are committed to improve health and education of school-aged children, but seek clear policy and technical guidance as to the optimal approach to address malaria and improved literacy. …”
Publicado 2010
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15879por Lakowski, J., Baron, M., Bainbridge, J., Barber, A.C., Pearson, R.A., Ali, R.R., Sowden, J.C.“…Crx-expressing cells were flow-sorted from the developing retina of CrxGFP transgenic mice and transplanted into adult recipient retinae; CrxGFP is a marker of cone and rod photoreceptor commitment. Only the embryonic-stage Crx-positive donor cells integrated within the outer nuclear layer of the recipient and differentiated into new cones, whereas postnatal cells generated a 10-fold higher number of rods compared with embryonic-stage donors. …”
Publicado 2010
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15880por Gonzalez, Candela R, Matzkin, María E, Frungieri, Mónica B, Terradas, Claudio, Ponzio, Roberto, Puigdomenech, Elisa, Levalle, Oscar, Calandra, Ricardo S, Gonzalez-Calvar, Silvia I“…CONCLUSIONS: In conclusion, the high levels of mRNA and protein expression of the TGF-β1 system in patients with LCH, particularly ALK1 and its correlation with endoglin, suggest that these proteins acting in concert might be, at least in part, committed actors in the Leydig cell hyperplasia.…”
Publicado 2010
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