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16281por Bielecki, Piotr, Riesenfeld, Samantha J., Hütter, Jan-Christian, Triglia, Elena Torlai, Kowalczyk, Monika S., Ricardo-Gonzalez, Roberto R., Lian, Mi, Vesely, Maria C. Amezcua, Kroehling, Lina, Xu, Hao, Slyper, Michal, Muus, Christoph, Ludwig, Leif S., Christian, Elena, Tao, Liming, Kedaigle, Amanda J., Steach, Holly R., York, Autumn G., Skadow, Mathias H., Yaghoubi, Parastou, Dionne, Danielle, Jarret, Abigail, McGee, Heather M., Porter, Caroline B. M., Licona-Limón, Paula, Bailis, Will, Jackson, Ruaidhrí, Gagliani, Nicola, Gasteiger, Georg, Locksley, Richard M., Regev, Aviv, Flavell, Richard A.“…However, it is not known whether this response is initiated by pre-committed ILCs or by cell-state transitions. Here we show that the induction of psoriasis in mice by IL-23 or imiquimod reconfigures a spectrum of skin ILCs, which converge on a pathogenic ILC3-like state. …”
Publicado 2021
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16282por Harris, Toi B., Nanda, Anil, Sargsyan, Lilit A., Chen, Wei-Jung A., Christner, Jennifer G.“…As developments to improve purpose and professional satisfaction emerge, the Texas Medical Association Committee on Physician Health and Wellness (PHW) is committed to providing the vehicle for a statewide collaboration and illuminating the path forward. …”
Publicado 2021
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16283por Kouwijzer, Ingrid, Valent, Linda J.M., Post, Marcel W.M., Wilders, Lise M., Grootoonk, Anneke, van der Woude, Lucas H.V., de Groot, Sonja“…CONCLUSION: Physical capacity showed an increase during the training period and remained stable after 1-yr follow-up. Being (repeatedly) committed to a challenge might facilitate long-term exercise maintenance.…”
Publicado 2021
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16284por Nsoh, Marius, Tshimwanga, Katayi E, Ngum, Busi A, Mgasa, Avelina, Otieno, Moses O, Moali, Bokwena, Sirili, Nathanael, Atanga, Ndeso S, Halle-Ekane, Gregory E“…BACKGROUND: Antiretroviral therapy is a lifelong commitment that requires consistent intake of tablets to optimize health outcomes, attain and maintain viral suppression. …”
Publicado 2021
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16285por Calibo, Anthony Pascual, De Leon Mendoza, Socorro, Silvestre, Maria Asuncion, Murray, John Charles Scott, Li, Zhao, Mannava, Priya, Kitong, Jacqueline, Quiazon, Mark Benjamin, Sobel, Howard Lawrence“…Expansion was led by the government which committed resources and formed partnerships with development partners and non-governmental organisations. …”
Publicado 2021
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16286por Giorni, Chiara, Rizza, Alessandra, Favia, Isabella, Amodeo, Antonio, Chiusolo, Fabrizio, Picardo, Sergio G., Luciani, Matteo, Di Felice, Giovina, Di Chiara, Luca“…Moreover, it exposes the efforts and the collaborations among different specialized centers, which are committed to an ongoing learning in order to minimize major complications in this special pediatric population. …”
Publicado 2021
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16287por Malik, Romana Fattimah, Buljac-Samardžić, Martina, Amajjar, Ihsane, Hilders, Carina G J M, Scheele, Fedde“…The culture themes’ teamwork and commitment were not specific for an open culture, contradicting the patient safety literature. …”
Publicado 2021
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16288por Files, Benjamin T., Pollard, Kimberly A., Oiknine, Ashley H., Khooshabeh, Peter, Passaro, Antony D.“…Trait regulatory focus was measured, and participants were randomly assigned to one of three conditions: points gain, points loss, and informative‐only feedback. Participants committed too few errors to reliably model ERN effects. …”
Publicado 2021
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16289por B.M. Mansour, Merrihan, Abdelkader, Tamer, Hashem, Mohamed, El-Horbaty, El-Sayed M.“…This paper presents an integrated three-tier trust management framework that evaluates cloud service providers in three main domains: Tier I, which evaluates service provider compliance to the agreed upon service level agreement; Tier II, which computes the processing performance of a service provider based on its number of successful processes; and Tier III, which measures the violations committed by a service provider, per computational interval, during its processing in the MEC network. …”
Publicado 2021
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16290por Whiffin, Charlotte Jane, Smith, Brandon George, Esene, Ignatius N, Karekezi, Claire, Bashford, Tom, Mukhtar Khan, Muhammad, Hutchinson, Peter John, Kolias, Angelos G, Fontoura Solla, Davi Jorge, Paiva, Wellingson S, Figaji, Anthony“…DESIGN: This was a two-stage inductive qualitative study situated within the naturalistic paradigm. This study committed to an interpretivist way of knowing (epistemology), and considered reality subjective and multiple (ontology). …”
Publicado 2021
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16291por Hu, Pengjie, Ding, Hao, Shen, Lan, He, Guang-Jun, Liu, Huimin, Tian, Xiuyun, Tao, Changyu, Bai, Xiangzheng, Liang, Jingnan, Jin, Cheng, Xu, Xinping, Yang, Ence, Wang, Linqi“…Overall, our findings discover an unprecedented and conserved cell wall biosynthesis-dependent fungal differentiation commitment mechanism, which enables the signal specificity of pathogenicity-related dimorphism induced by GlcN in Cryptococcus pathogens.…”
Publicado 2021
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16292por Hamilton, Clayon B, Dehnadi, Maryam, Snow, M Elizabeth, Clark, Nancy, Lui, Michelle, McLean, Janet, Mamdani, Hussein, Kooijman, Allison L, Bubber, Vikram, Hoefer, Tammy, Li, Linda C“…There were six structure themes: engagement plan, level of engagement, time and timing of engagement, format and composition, commitment to support and environment. There were four process themes: objectives, engagement approach, communication and engagement activities. …”
Publicado 2021
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16293“…Shifting supply chains nearby, decreasing the suppliers base, increasing the digitalization of supply chains are essential tactics companies have to start committing to.…”
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16294por Mentink, Marit, Noordman, Janneke, Busch, Martine, van Vliet, Liesbeth, Timmer-Bonte, Johanna (Anja), van Dulmen, Sandra“…Dissemination of the toolbox is covered by the commitment of stakeholder parties. ETHICS AND DISSEMINATION: The Medical Ethics Committee Arnhem-Nijmegen declared the study was exempted from formal approval under the Dutch Medical Research Involving Human Subjects Act. …”
Publicado 2021
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16295“…A full embrace of telehealth, collaborative policy-making among the many AMC constituencies, and committing fully to being in the vanguard of the transition to value-based care form the solution set offered.…”
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16296“…RESULTS: The district audit committees had significant challenges to develop appropriate recommendations and action plans, involving: 1) non-informative audit tool provides unreliable data for review; 2) unstandardized clinical indicators and the practice of “sharp downward, blunt upward”; 3) unaccountable hospital support and lack of leadership commitment, and 4) blaming culture, minimal training, and insufficient MDA committee’ skills. …”
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16297por Pillai, Viju Vijayan, Koganti, Prasanthi P., Kei, Tiffany G., Gurung, Shailesh, Butler, W. Ronald, Selvaraj, Vimal“…Inhibition of ALK4/5/7 to block TGFβ/activin/nodal signaling together with GSK3β and MEK1/2 supported robust in vitro self-renewal of naïve biPSCs with unvarying colony morphology, steady expansion, expected pluripotency gene expression and committed differentiation plasticity. Core similarities between biPSCs and stem cells of the 16-cell-stage bovine embryo indicated a stable ground state of pluripotency; this allowed us to reliably gain predictive understanding of signaling in bovine pluripotency using systems biology approaches. …”
Publicado 2021
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16298“…RESULTS: Findings from the study revealed that determinants that influenced the successful implementation of the NTDs programme include donor support, education and training, partnerships, reliability of the health structure, integrative nature of the programme and management commitment. These determining factors cut across the inner settings of the implementing agency and the external environment. …”
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16299por Green, S., Tuck, S., Long, J., Green, T., Green, A., Ellis, P., Haire, A., Moss, C., Cahill, F., McCartan, N., Brown, L., Santaolalla, A., Marsden, T., Justo, M. Rodriquez, Hadley, J., Punwani, S., Attard, G., Ahmed, H., Moore, C. M., Emberton, M., Van Hemelrijck, M.“…As quoted by one of the study participants, “the more we present the benefits and opportunities to patients and the public, the more research commitment we obtain, and the sooner critical clinical questions such as PCa diagnostics will be addressed”.…”
Publicado 2021
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16300“…They provide an illustrative overview of longitudinal qualitative research in medical education, and end with practical advice, or pearls, for medical education investigators interested in using this research approach: collecting data recursively; analysing longitudinal data in three strands; addressing mutual reflexivity; using theory to illuminate time; and making a long‐term commitment to longitudinal qualitative research. CONCLUSIONS: Longitudinal qualitative research stretches investigators to think differently about time and undertake more complex analyses to understand dynamic lived experiences. …”
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