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  1. 16601
    “…Biotin is an essential co-factor for acetyl-CoA carboxylase (ACC) the enzyme involved in the synthesis of malonyl-CoA, a committed precursor, needed for fatty acid synthesis. …”
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    Ligand Specificity of Group I Biotin Protein Ligase of Mycobacterium tuberculosis
  2. 16602
    por García-González, Francisco
    Publicado 2008
    “…Furthermore, asymmetries among males in the errors committed when estimating sperm competitive abilities are likely to exist as long as males exhibit variation in sperm competitiveness. …”
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    The relative nature of fertilization success: Implications for the study of post-copulatory sexual selection
  3. 16603
    “…In 2004 the EC expressed its commitment to the development of a harmonised approach to human biomonitoring (HBM) by including an action in the EU Environment and Health Strategy to develop a Human Biomonitoring Pilot Study. …”
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    Human biomonitoring data interpretation and ethics; obstacles or surmountable challenges?
  4. 16604
    “…Complementation studies with PPARγ but not C/EBPα rescued the differentiation block in committed adipocytic precursors expressing FUS-DDIT3. …”
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    FUS-DDIT3 Prevents the Development of Adipocytic Precursors in Liposarcoma by Repressing PPARγ and C/EBPα and Activating eIF4E
  5. 16605
    “…The most important promoting factors were the formation of a core team committed to quality and improvement, and the clinic leadership that was supported strongly by the team members. …”
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    Tailoring an intervention to the context and system redesign related to the intervention: A case study of implementing shared medical appointments for diabetes
  6. 16606
    “…Screening decisions should reflect duration of travel, tuberculosis incidence, and commitment to treat latent infection.…”
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    Tuberculosis screening of travelers to higher-incidence countries: A cost-effectiveness analysis
  7. 16607
    “…A related property of the ribosome, [Formula: see text] , has units of a-protein per time per total RNA with the relationship [Formula: see text] = ρ(a )T(a(max)), where ρ(a )represents the fraction of total RNA committed to translation output of P(a )from gene a message. …”
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    A systems approach to model natural variation in reactive properties of bacterial ribosomes
  8. 16608
    por Mahmud, Ifte, Kim, David
    Publicado 2000
    “…This is attributed to the Suffern facility employees' commitment to reduce cycle time, improve efficiency, and maintain high level of regulatory compliance. …”
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    Implementation of and experiences with new automation
  9. 16609
    “…Furthermore, early events occurring after the disruption of DNA replication (accumulation of RPA foci and RPA34 hyperphosphorylation) in ATR- or Chk1-depleted cells committed to apoptosis are not detected in ATM-depleted cells. …”
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    ATR and Chk1 Suppress a Caspase-3–Dependent Apoptotic Response Following DNA Replication Stress
  10. 16610
    “…The Zinc Finger Consortium, a group of academic laboratories committed to the development of engineered zinc finger technology, recently described the first rapid, highly effective, and publicly available method for engineering zinc finger arrays. …”
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    Rapid Mutation of Endogenous Zebrafish Genes Using Zinc Finger Nucleases Made by Oligomerized Pool ENgineering (OPEN)
  11. 16611
    “…Finally, further characterization of the PDX1(+) cells suggests that they represent foregut endoderm not yet committed to pancreatic, posterior stomach, or duodenal endoderm. …”
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    FGF4 and Retinoic Acid Direct Differentiation of hESCs into PDX1-Expressing Foregut Endoderm in a Time- and Concentration-Dependent Manner
  12. 16612
    “…BACKGROUND: Despite Hong Kong government's official commitment to the development of traditional Chinese medicine (TCM) over the last ten years, there appears to have been limited progress in public sector initiated career development and postgraduate training (PGT) for public university trained TCM practitioners. …”
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    Postgraduate education for Chinese medicine practitioners: a Hong Kong perspective
  13. 16613
    por Agalliu, Dritan, Schieren, Ira
    Publicado 2009
    “…Exposure of progenitors to Bone Morphogenetic Protein-4 induces some dorsal cell type characteristics in their progeny, revealing that lineage-restricted progenitor subtypes are not fully committed to their fates. CONCLUSION: These findings support a model whereby continuous Shh signaling is required to maintain the identity of ventral progenitors isolated from the spinal cord, including motor neuron progenitors, after in vitro expansion. …”
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    Heterogeneity in the developmental potential of motor neuron progenitors revealed by clonal analysis of single cells in vitro
  14. 16614
    “…One of the immediate early genes, early growth response gene 1 (EGR-1), has been implicated in differentiation of human monoblastoma cells along the monocytic commitment following treatment with phorbol ester. EGR-1 has been thought to work as a modifier of monopoiesis, but the precise function of EGR-1 in monocytic differentiation has not been fully elucidated. …”
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    Genome-wide investigation of in vivo EGR-1 binding sites in monocytic differentiation
  15. 16615
    “…In search for new therapeutic approaches, Bone Morphogenetic Proteins (BMPs) induce astroglial commitment in GBM-derived cells in vitro. However, we recently suggested that hypoxia, which is characteristic of the brain niche where GBM reside, strongly counter-acts BMP effects. …”
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    Molecular Mechanisms of HIF-1α Modulation Induced by Oxygen Tension and BMP2 in Glioblastoma Derived Cells
  16. 16616
    “…A previous analysis of World Records (WR) has revealed the potential limits of human physiology through athletes' personal commitment. The impact of political factors on sports has only been studied through Olympic medals and results. …”
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    Success in Developing Regions: World Records Evolution through a Geopolitical Prism
  17. 16617
    “…Facilitators were rated highly for their knowledge and commitment, as well as their ability to identify problems and help participants as required. …”
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    Experiences of training and implementation of integrated management of childhood illness (IMCI) in South Africa: a qualitative evaluation of the IMCI case management training course
  18. 16618
    “…Investigation of bone marrow cells showed that these became apoptotic within seven days after poly injection. Committed myeloid progenitor cells and cells with long term reconstituting potential were lost from bone marrow within four days after poly injection. …”
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    THOC5/FMIP, an mRNA export TREX complex protein, is essential for hematopoietic primitive cell survival in vivo
  19. 16619
    “…We recently reported that IL-4+TGF-β directs mouse CD4(+)CD25(−)CD62L(+) T cells to commit to inflammatory IL-9 producing CD4(+) T cells. …”
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    Human CD4(+) Memory T Cells Can Become CD4(+)IL-9(+) T Cells
  20. 16620
    “…Following the 2007 Australian Federal election, the new Labour government brought with it a refreshing commitment to a more inclusive and strategic style of government. …”
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    Paving Pathways: shaping the Public Health workforce through tertiary education
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