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  1. 16661
    “…The Avahan transition strategy focuses on three activities: (1) enhancing capacities among communities, non-governmental organizations (NGOs), and government entities, in line with India's national AIDS control strategy; (2) aligning technical and managerial aspects of Avahan programs with government norms and standards; and (3) promoting and sustaining commitment to services for most-at-risk populations. …”
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    Sustainability of donor programs: evaluating and informing the transition of a large HIV prevention program in India to local ownership
  2. 16662
    “…The dissolved CO(2 )concentration in the fermentation broth could strongly regulate the metabolic flux of carbon and the activity of phosphoenolpyruvate (PEP) carboxykinase, which are the important committed steps for the biosynthesis of succinic acid by Actinobacillus succinogenes. …”
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    Significance of CO(2 )donor on the production of succinic acid by Actinobacillus succinogenes ATCC 55618
  3. 16663
    “…In certain systems, cells defer differentiation for extended time periods after the signal appears, proliferating through multiple rounds of cell division before committing to a new fate. How can cells set a deferral time much longer than the cell cycle? …”
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    Pulsed Feedback Defers Cellular Differentiation
  4. 16664
    “…Hematopoietic stem cells (HSCs) exhibited the highest susceptibility to N-Myc-induced pre-B ALL/LBL versus lymphoid progenitors, myeloid progenitors and committed progenitor B cells. N-Myc was able to induce pre-B ALL/LBL directly from progenitor B cells in the absence of Ink4a and Arf. …”
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    Ink4a and Arf are crucial factors in the determination of the cell of origin and the therapeutic sensitivity of Myc-induced mouse lymphoid tumor
  5. 16665
    “…RESULTS: Examined persons applied several modes of committing suicide: pharmacological drugs, exsanguination, hanging, jumping from a height, asphyxia, poisoning, and throwing oneself under a moving car. …”
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    Indirect (chronic) self-destructiveness and modes of suicide attempts
  6. 16666
    “…RESULTS: Based on the three cases, we argue that prohibitive laws and governments’ reluctance to institute and implement comprehensive rights approaches to SRH, lack of political leadership and commitment to funding SRHR policies and programmes, and dominant negative cultural framing of women’s issues present the major obstacles to operationalising SRH rights. …”
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    Operationalising sexual and reproductive health and rights in sub-Saharan Africa: constraints, dilemmas and strategies
  7. 16667
    “…All women who answered positively to at least one of the questions about specific acts of physical or sexual violence committed by a partner towards her at any point in her life were considered to have experienced intimate partner violence. …”
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    Induced abortion, pregnancy loss and intimate partner violence in Tanzania: a population based study
  8. 16668
    “…In such assessments, a commitment to community participation and empowerment is at the heart of the WHO European Healthy Cities Network, reflecting its origins in health for all and the Ottawa Charter for Health Promotion. …”
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    Community based needs assessment in an urban area; A participatory action research project
  9. 16669
    “…CONCLUSIONS/SIGNIFICANCE: Effective health strengthening efforts may require intensive development of managerial problem solving skills, strong relationships with government offices that oversee front-line providers, and committed community leadership to succeed.…”
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    A Systems Approach to Improving Rural Care in Ethiopia
  10. 16670
    “…Fifty-one of the disciplined physicians committed 64 repeat offences, accounting for a total of 113 (19%) offences. …”
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    The characteristics of physicians disciplined by professional colleges in Canada
  11. 16671
    “…The diverse social context for health in an urban poor setting calls for a decentralized planning and partnership strategy, but with central level commitment towards policy guidance and financing of pro-poor urban health strategies. …”
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    Taking action on the social determinants of health: improving health access for the urban poor in Mongolia
  12. 16672
    “…MATERIALS, METHODS AND RESULTS: The primary CB AC133+ EPC culture contained mainly EPCs and long term in vitro conditions facilitated the maintenance of these cells in a state of commitment toward endothelial lineage. At days 15–20 and 25–30 of the primary culture, the cells were labeled with FePro and cryopreserved for a few weeks. …”
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    MRI Tracking of FePro Labeled Fresh and Cryopreserved Long Term In Vitro Expanded Human Cord Blood AC133+ Endothelial Progenitor Cells in Rat Glioma
  13. 16673
    “…BACKGROUND: The Model of Health Care Empowerment (HCE) defines HCE as the process and state of being engaged, informed, collaborative, committed, and tolerant of uncertainty regarding health care. …”
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    Preliminary support for the construct of health care empowerment in the context of treatment for human immunodeficiency virus
  14. 16674
    “…However, a question about the actual in vivo nitrogen donor for single-domain members of the NADS family remained open: Is it glutamine hydrolyzed by a committed (but yet unknown) glutaminase subunit, as in most ATP-dependent amidotransferases, or free ammonia as in glutamine synthetase? …”
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    Glutamine versus Ammonia Utilization in the NAD Synthetase Family
  15. 16675
    “…Among the genes in pOLs that were still repressed by Ezh2 were most prominently those associated with neuronal and astrocytic committed cell lineages. Suppression of Ezh2 activity in NSCs caused loss of stem cell characteristics, blocked their proliferation and ultimately induced apoptosis. …”
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    Dynamic Changes in Ezh2 Gene Occupancy Underlie Its Involvement in Neural Stem Cell Self-Renewal and Differentiation towards Oligodendrocytes
  16. 16676
    por Barbui, Corrado, Saraceno, Benedetto
    Publicado 2012
    “…Theoretically, Member States should be aware of the resolution and support its implementation at their respective national level, but in practice political commitment may not be high enough, and technical and financial resources made available may be limited. …”
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    Geneva calling: WHO resolution on mental disorders
  17. 16677
    “…Prevention spend needs to be considered purposefully, resulting in a strategic commitment to spending. The role of economics in this process is to provide evidence demonstrating that information and support can be provided cost effectively to individuals to change their lifestyles thus avoiding lifestyle related morbidity and mortality. …”
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    Making the economic case for prevention – a view from Wales
  18. 16678
    “…Furthermore, the successful replication of the OSCC model in other similar settings requires that the model – and the system supporting it – needs to be flexible enough to allow adaptation of the service model to different types of facilities and levels of care, and to available resources and thus better support providers committed to delivering care to abused women.…”
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    An integrated health sector response to violence against women in Malaysia: lessons for supporting scale up
  19. 16679
    por Chassin, Mark R
    Publicado 2012
    “…Health care organizations will have to undertake three interrelated changes to get substantially closer to the superlative safety records of other industries: leadership commitment to zero major quality failures, widespread implementation of highly effective process improvement methods, and the adoption of all facets of a culture of safety. …”
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    Quality of care: how good is good enough?
  20. 16680
    “…With this motif, a population of naïve CD4(+) T cells can integrate the signals from their environment to generate a functionally diverse population with robust commitment of individual cells. Notably, two positive feedback loops in this network motif govern three bistable switches, which in turn, give rise to three types of heterogeneous differentiated states, depending upon particular combinations of input signals. …”
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    A simple theoretical framework for understanding heterogeneous differentiation of CD4(+) T cells
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