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  1. 17561
    por Ringborg, Ulrik, Berns, Anton, Celis, Julio E., Heitor, Manuel, Tabernero, Josep, Schüz, Joachim, Baumann, Michael, Henrique, Rui, Aapro, Matti, Basu, Partha, Beets‐Tan, Regina, Besse, Benjamin, Cardoso, Fátima, Carneiro, Fátima, van den Eede, Guy, Eggermont, Alexander, Fröhling, Stefan, Galbraith, Susan, Garralda, Elena, Hanahan, Douglas, Hofmarcher, Thomas, Jönsson, Bengt, Kallioniemi, Olli, Kásler, Miklós, Kondorosi, Eva, Korbel, Jan, Lacombe, Denis, Carlos Machado, José, Martin‐Moreno, José M., Meunier, Francoise, Nagy, Péter, Nuciforo, Paolo, Oberst, Simon, Oliveiera, Júlio, Papatriantafyllou, Maria, Ricciardi, Walter, Roediger, Alexander, Ryll, Bettina, Schilsky, Richard, Scocca, Grazia, Seruca, Raquel, Soares, Marta, Steindorf, Karen, Valentini, Vincenzo, Voest, Emile, Weiderpass, Elisabete, Wilking, Nils, Wren, Amanda, Zitvogel, Laurence
    Publicado 2021
    “…An important outcome of the Summit was the presentation of the Porto Declaration, which called for a collective and committed action throughout Europe to develop the cancer research infrastructures indispensable for fostering innovation and decreasing inequalities within and between member states. …”
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    The Porto European Cancer Research Summit 2021
  2. 17562
    “…CONCLUSIONS: Contributing factors to achievement of the learning outcomes were supervisors’ commitment and experience, and the projects being suitable for the time frame and having a clearly stated research question. …”
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    Faculty perceptions of factors that indicate successful educational outcomes of medical students’ research projects: a focus group study
  3. 17563
    “…OBJECTIVE: We initiated a family medicine specialty training program (FMSTP) to increase the number of well-trained physicians who have the knowledge, skills, and commitment to meet the health needs of the Liberian people. …”
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    The Role of Family Medicine Training in Addressing Workforce Challenges in Rural Liberia – Early Implementation Experience
  4. 17564
    “…CONCLUSIONS: We reach the conclusion that digital meetings with public contributors is possible, but that researchers need to make a commitment and actively work to solve practical issues. …”
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    What has the COVID-19 pandemic taught us about conducting patient and public involvement remotely? Insights from a series of digital meeting observations
  5. 17565
    “…The five key topics are: (I) ‘The medication is reviewed regularly and in defined situations’, (II) ‘The medication is reviewed in a structured manner’, (III) ‘The medication is monitored in a structured manner’, (IV) ‘All healthcare professionals are committed to an optimal interprofessional collaboration’ and (V) ‘Residents are actively involved in medication process’. …”
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    Quality standards for safe medication in nursing homes: development through a multistep approach including a Delphi consensus study
  6. 17566
    “…Suboptimal nutritional supply, lack of supportive supervision, lack of adequate workforce, staff turn-over, the sudden withdrawal of partners, and weak link with social service were the barriers at the organization level. Lack of commitment was reported as the only barrier at the care provider level, and socioeconomic status of patients, sharing and selling of supplies, perceived improved status, and perceived stigma were identified as the major barriers for the implementation of nutrition assessment, counseling, and support service. …”
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    Barriers and facilitators of nutrition assessment, counseling, and support for tuberculosis patients: a qualitative study
  7. 17567
    “…This required the research team to be highly responsive to both co-production inputs and data gathered in formally conducted studies, and to be committed to working through the implications for intervention design. …”
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    Addressing complex pharmacy consultations: methods used to develop a person-centred intervention to highlight alcohol within pharmacist reviews of medications
  8. 17568
    “…Functional depletion of MLPH in prostate organoids, by CRISPR/Cas9 mutation, impacted lineage commitment of progenitor cells promoting luminal versus basal cell differentiation and on resistance to androgen deprivation. …”
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    Evolutionary selection of alleles in the melanophilin gene that impacts on prostate organ function and cancer risk
  9. 17569
    “…Engaging patients as active partners on research teams enhances the potential of strengthened patient engagement, increased patient commitment to treatment, and leads to improved health outcomes. …”
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    Beyond the role of participant: a firsthand account of the experiences of a patient-oriented research team
  10. 17570
    “…These included the time of day interviews occur, recall ease, level of commitment required, perceived survey value, emotional response to surveys, and interviewer positionality. …”
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    Assessing the social validity of a brief dietary survey for Sri Lankan adults with a focus on gender: a qualitative study
  11. 17571
    “…By cell-to-cell contact, M1 macrophages induced Notch signaling activation in VSMCs which committed contractile-synthetic conversion. Rivaroxaban treatment and Dll4 silencing incapacitated macrophage in inducing phenotypic conversion of VSMCs upon cell-to-cell contact. …”
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    Rivaroxaban Suppresses Atherosclerosis by Inhibiting FXa-Induced Macrophage M1 Polarization-Mediated Phenotypic Conversion of Vascular Smooth Muscle Cells
  12. 17572
    “…OBJECTIVE: This study aimed to test a serial mediation model of an Acceptance and Commitment Therapy (ACT) smartphone intervention for smoking cessation. …”
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    Mechanisms of Smartphone Apps for Cigarette Smoking Cessation: Results of a Serial Mediation Model From the iCanQuit Randomized Trial
  13. 17573
    “…BACKGROUND: We conducted a randomized controlled trial to evaluate the effectiveness of acceptance and commitment therapy (ACT) delivered via a mobile phone messaging robot to patients who had their total hip arthroplasty or total knee arthroplasty procedures postponed due to the COVID-19 pandemic. …”
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    A Psycholgical Intervention Delivered by Automated Mobile Phone Messaging Stabilized Hip and Knee Function During the COVID-19 Pandemic: A Randomized Controlled Trial
  14. 17574
    “…These behaviors or events included integrin clustering, focal adhesion (FA) complex accumulation and activation, cytoskeleton rearrangement, protein cyto-nuclei shuttling and activation (e.g., Yes-associated protein (YAP), catenin, etc.), cellular compartment reorganization, gene expression, and further cell biology modulation (e.g., spreading, migration, proliferation, lineage commitment, etc.). Based on them, current in vitro and in vivo hydrogel applications that mainly covered diseases models, various cell delivery protocols for tissue regeneration and disease therapy, smart drug carrier, bioimaging, biosensor, and conductive wearable/implantable biodevices, etc. were further summarized and discussed. …”
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    Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity
  15. 17575
    “…Our results provide the first genome-wide analysis of the chromatin landscape following VPA-induced differentiation in mESCs and provide new mechanistic insight into the intricate molecular processes that govern departure from pluripotency and early lineage commitment. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13072-021-00432-5.…”
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    Changes in chromatin accessibility landscape and histone H3 core acetylation during valproic acid-induced differentiation of embryonic stem cells
  16. 17576
    por Wang, Hui, Yu, Cun
    Publicado 2022
    “…Professor Byoungho Lee, who graduated from the University of California at Berkeley and currently works at Seoul National University in South Korea, has been committed to the development of optical components used in VR and AR technologies. …”
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    Light People: Professor Byoungho Lee
  17. 17577
    “…In the intervention group, practitioners will receive an intervention comprising: (1) training to support appropriate antibiotic prescribing for RTI, (2) a computer-based treatment decision support system, (3) virtual peer support, (4) a leaflet for patients and (5) a letter of commitment to optimise antibiotic use to display in their clinic. …”
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    Cluster randomised controlled trial to assess a tailored intervention to reduce antibiotic prescribing in rural China: study protocol
  18. 17578
    “…However, once scaled, embedding digital health solutions into the fabric of the health system was hampered by challenges related to transitioning management and ownership to government partners; overcoming government procurement hurdles; and establishing committed funding streams in government budgets. Strong data governance, continued engagement with FLHWs and building a robust evidence base, while identified in the literature as critical for sustainability, did not feature strongly among respondents. …”
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    A tale of ‘politics and stars aligning’: analysing the sustainability of scaled up digital tools for front-line health workers in India
  19. 17579
    “…The roles of organizational commitment (OC), leadership autonomy support (LAS), and organizational culture in relation to hospital employees’ OVI are examined. …”
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    Promoting organizational vision integration among hospital employees
  20. 17580
    “…A further challenge highlighted included committing time to work across the four pillars of advanced practice, particularly the research pillar. …”
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    Nationwide evaluation of the advanced clinical practitioner role in England: a cross-sectional survey
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