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35861por Bodor, Dani L., Valente, Luis P., Mata, João F., Black, Ben E., Jansen, Lars E. T.“…Strikingly, stable retention is restricted to the CENP-A/H4 core of the nucleosome, which we find to outlast general chromatin across several cell divisions. We further show that cell cycle timing of CENP-A assembly is independent of centromeric DNA sequences and instead is mediated by the CENP-A targeting domain. …”
Publicado 2013
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35862por Whitfield, Zachary J., Chisholm, Jennifer, Hawley, R. Scott, Orr-Weaver, Terry L.“…Oocytes are stockpiled with proteins and mRNA that are required to drive the initial mitotic divisions of embryogenesis. But are there proteins specific to meiosis whose levels must be decreased to begin embryogenesis properly? …”
Publicado 2013
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35863“…Frameshifting indels are indels that have a length that is not divisible by 3 and subsequently cause frameshifts. …”
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35864“…Mitotic analysis clearly revealed the azo dye induced endpoint deviation like reduction in the frequency of normal divisions in a dose dependent manner. Mitotic divisions in the control sets were found to be perfectly normal while dose based reduction in MI was registered in the treated sets. …”
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35865“…Based on a top-down analysis of the alignments of nation states, Huntington famously concluded that the axes of international geo-political conflicts had reverted to the ancient cultural divisions that had characterized most of human history. …”
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35866por Najas, Sònia, Arranz, Juan, Lochhead, Pamela A., Ashford, Anne L., Oxley, David, Delabar, Jean M., Cook, Simon J., Barallobre, María José, Arbonés, Maria L.“…These alterations promote asymmetric proliferative divisions at the expense of neurogenic divisions, producing a deficit in cortical projection neurons that persists in postnatal stages. …”
Publicado 2015
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35867por Grey, Corinne, Espeut, Julien, Ametsitsi, Rachel, Kumar, Rajeev, Luksza, Malgorzata, Brun, Christine, Verlhac, Marie-Hélene, Suja, José Angél, de Massy, Bernard“…We conclude that mouse SKAP, while being dispensable for somatic cell divisions, has an important role in the successful outcome of male gametogenesis. …”
Publicado 2016
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35868por Fabbretti, Fabiana, Iannetti, Ilaria, Guglielmi, Loredana, Perconti, Susanna, Evangelistella, Chiara, Proietti De Santis, Luca, Bongiorni, Silvia, Prantera, Giorgio“…By confocal imaging, we characterized the NL modifications from mitotic stages, through meiotic divisions to sperm differentiation with an anti-laminDm0 antibody against the major component of the Drosophila NL. …”
Publicado 2016
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35869por Picco, Noemi, García-Moreno, Fernando, Maini, Philip K, Woolley, Thomas E, Molnár, Zoltán“…We find that the timing of a switch in favor of symmetric neurogenic divisions produces the highest variation in cortical neuronal numbers. …”
Publicado 2018
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35870“…Continuous spermatogenesis in post-pubertal mammals is dependent on spermatogonial stem cells (SSCs), which balance self-renewing divisions that maintain stem cell pool with differentiating divisions that sustain continuous sperm production. …”
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35871“…We conclude that pharmacological activation of cortical AR regulates visual perception and adaptive behavior through a divisive gain control of visual responses.…”
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35872por Gao, Ziyue, Moorjani, Priya, Sasani, Thomas A., Pedersen, Brent S., Quinlan, Aaron R., Jorde, Lynn B., Amster, Guy, Przeworski, Molly“…The textbook view that most germline mutations in mammals arise from replication errors is indirectly supported by the fact that there are both more mutations and more cell divisions in the male than in the female germline. …”
Publicado 2019
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35873“…A hallmark of the neocortex are the cortical neurons, which are generated from divisions of neural progenitor cells (NPCs) during development, and which constitute a key feature of the well-organized layered structure of the neocortex. …”
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35874por Uchimura, Arikuni, Matsumoto, Hirotaka, Satoh, Yasunari, Minakuchi, Yohei, Wakayama, Sayaka, Wakayama, Teruhiko, Higuchi, Mayumi, Hashimoto, Masakazu, Fukumura, Ryutaro, Toyoda, Atsushi, Gondo, Yoichi, Yagi, Takeshi“…De novo mutations accumulate with zygotic cell divisions. However, the occurrence of these mutations and the way they are inherited by somatic cells and germ cells remain unclear. …”
Publicado 2022
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35875por Cohen, Hillel P.“…Sandoz and Novartis International were considered as separate entities, but are both are divisions of the same parent company. When considered as a single entity for purposes of tracking publications, Sandoz-Novartis is among the leaders in the number of articles published about biosimilars.…”
Publicado 2018
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35876“…Two of four isolates subcultured ∼20 times (∼500 cell divisions) became haploid. These strains were capable of mating with wild-type haploids to produce diploid progeny capable of undergoing meiosis to produce four viable spores.…”
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35877“…Cell Biol. http://dx.doi.org/10.1083/jcb.201505037) report that cell fate determinant and tumor suppressor Numb imposes asymmetric cell divisions in mammary stem cells by regulating p53. …”
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35878“…Descriptions of somatic cell divisions were made as early as the eighteenth and nineteenth centuries with varying degrees of accuracy. …”
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35879por Rinn, John L, Bondre, Chanda, Gladstone, Hayes B, Brown, Patrick O, Chang, Howard Y“…A set of 337 genes that varied according to these positional divisions was able to group all 47 samples by their anatomic sites of origin. …”
Publicado 2006
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35880“…This newly optimized dose pole with single 600 mg (height: 99–110 cm), ¾ (height: 83–99 cm) and ½ (height: 66–83 cm) tablet divisions, also reduces drug waste and facilitates inclusion of preschool-aged children. …”
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