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  1. 36481
    “…Here, we show that single unattached kinetochores depleted of CENP-E cannot block entry into anaphase, resulting in aneuploidy in 25% of divisions in primary mouse fibroblasts in vitro and in 95% of regenerating hepatocytes in vivo. …”
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    Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss
  2. 36482
    “…However, despite having undergone the same number of divisions, cells that expand in the absence of a third signal fail to develop cytolytic effector function. …”
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    Signal 3 Determines Tolerance versus Full Activation of Naive CD8 T Cells: Dissociating Proliferation and Development of Effector Function
  3. 36483
    por Callaghan, John J., Grun, Paul
    Publicado 1961
    “…The chromosomes seen in mitotic divisions of all three species had the same amount of label in euchromatic as heterochromatic areas. …”
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    INCORPORATION OF C(14)-LABELED MALEIC HYDRAZIDE INTO THE ROOT-TIP CELLS OF ALLIUM CERNUUM, VICIA FABA, AND TRADESCANTIA PALUDOSA
  4. 36484
    Publicado 1992
    “…After developing a technique to separate the very resistant egg shell from the embryos, we studied the cell divisions during early embryogenesis by immunochemical and EM approaches. …”
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    Kinetochores and chromatin diminution in early embryos of Parascaris univalens
  5. 36485
    “…Integrin-mediated FSC anchoring is also essential for proper development of differentiating prefollicle cells that arise from asymmetrical FSC divisions. Our results support a model in which FSCs contribute to the formation and maintenance of their own niche by producing the integrin ligand, laminin A (LanA). …”
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    Integrins control the positioning and proliferation of follicle stem cells in the Drosophila ovary
  6. 36486
    “…Interestingly, Sam68 is associated with polyadenylated mRNAs in the cytoplasm during the meiotic divisions and in round spermatids, when it interacts with the translational machinery. …”
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    Sam68 regulates translation of target mRNAs in male germ cells, necessary for mouse spermatogenesis
  7. 36487
    por Bittles, Alan H
    Publicado 2005
    “…In many of the populations of the Indian sub-continent, these basic population divisions are compounded by a strict tradition of intra-community marriage and by marriage between close biological relatives. …”
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    Population stratification and genetic association studies in South Asia
  8. 36488
    “…When telomeres reach a critical length the cell will not further undergo cell divisions and become senescent or otherwise dysfunctional. …”
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    Telomere biology in healthy aging and disease
  9. 36489
    “…METHODS: A review of organizational theory and a qualitative study of 9 practices was used to design an intervention which was applied in four Divisions of General Practice and 26 urban practices. …”
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    Development and early experience from an intervention to facilitate teamwork between general practices and allied health providers: the Team-link study
  10. 36490
    “…Further, the viral latent oncoproteins EBNA3C was required to attenuate the EBV-induced DNA damage response We propose that heightened oncogenic activity in early cell divisions activates a growth-suppressive DDR which is attenuated by viral latency products to induce cell immortalization.…”
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    An ATM/Chk2-mediated DNA damage responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells
  11. 36491
    “…Many mutation events in microsatellite DNA sequences were traced to the first embryonic divisions. It was not known what makes the first replication cycles of embryonic DNA different from subsequent replication cycles. …”
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    A distinct first replication cycle of DNA introduced in mammalian cells
  12. 36492
    “…In this paper, we report a surprising gradual transition from meiosis to mitosis over the first eight divisions of the mouse embryo. The first cleavages still largely share the mechanism of spindle formation with meiosis, during which the spindle is self-assembled from randomly distributed microtubule-organizing centers (MTOCs) without centrioles, because of the concerted activity of dynein and kinesin-5. …”
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    The transition from meiotic to mitotic spindle assembly is gradual during early mammalian development
  13. 36493
    por Becker, Walter
    Publicado 2012
    “…The DYRK2 ortholog of C. elegans, MBK-2, triggers the proteasomal destruction of oocyte proteins after meiosis to allow the mitotic divisions in embryo development. This review summarizes the accumulating results that provide evidence for a general role of DYRKs in the regulation of protein stability.…”
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    Emerging role of DYRK family protein kinases as regulators of protein stability in cell cycle control
  14. 36494
    “…The roughex mutant neurons re-enter the mitotic cell cycle and progress without executing cytokinesis, unlike non-neuronal cells in the roughex mutant that perform complete cell divisions. After mitosis, the binucleated R8 neurons usually transport one daughter nucleus away from the cell body into the developing axon towards the brain in a kinesin-dependent manner resembling anterograde axonal trafficking. …”
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    Mitosis in Neurons: Roughex and APC/C Maintain Cell Cycle Exit to Prevent Cytokinetic and Axonal Defects in Drosophila Photoreceptor Neurons
  15. 36495
    “…BACKGROUND: The mandibular foramen (MF) is an opening on the internal surface of the ramus for divisions of the mandibular vessels and nerve to pass. …”
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    Significance of localization of mandibular foramen in an inferior alveolar nerve block
  16. 36496
    “…RESULTS: We introduce a new denoising algorithm that we call DADA (Divisive Amplicon Denoising Algorithm). Without training data, DADA infers both the sample genotypes and error parameters that produced a metagenome data set. …”
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    Denoising PCR-amplified metagenome data
  17. 36497
    “…In this paper, we propose that competition between two forces – the limitation and avoidance of chromosomal imbalances as a ciliate undergoes successive asexual divisions, and the costs of replicating massive genomes – is sufficient to explain this particular nuclear structure. …”
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    A Model for the Evolution of Extremely Fragmented Macronuclei in Ciliates
  18. 36498
    “…Heterochromatin causes epigenetic repression that can be transmitted through multiple cell divisions. However, the mechanisms underlying silencing and stability of heterochromatin are not fully understood. …”
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    HDAC mediated suppression of histone turnover promotes epigenetic stability of heterochromatin
  19. 36499
    “…This mechanism enables a rapid, tissue-specific response to nutritional changes, tailoring stem cell divisions and egg production to environmental conditions sufficient for progeny survival. …”
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    Diet controls Drosophila follicle stem cell proliferation via Hedgehog sequestration and release
  20. 36500
    “…The multilayered epidermis is established through a stratification program, which is accompanied by a shift from symmetric toward asymmetric divisions (ACD), a process under tight control of the transcription factor p63. …”
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    Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition
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