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36641“…To test whether this behavior is present also in other plant species and tissues we analyzed Arabidopsis, rye, wheat, Aegilops and barley centromeres during cell divisions and in interphase nuclei by immunostaining and FISH. …”
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36642por Arcaute, Elsa, Molinero, Carlos, Hatna, Erez, Murcio, Roberto, Vargas-Ruiz, Camilo, Masucci, A. Paolo, Batty, Michael“…At the larger scales, the observed hierarchical structures can be interpreted as regional fractures of Britain, observed in various forms, from natural boundaries, such as National Parks, to regional divisions based on social class and wealth such as the well-known North–South divide. …”
Publicado 2016
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36643por Nagalski, Andrzej, Puelles, Luis, Dabrowski, Michal, Wegierski, Tomasz, Kuznicki, Jacek, Wisniewska, Marta B.“…These new molecular divisions of the adult thalamic complex are defined by the combinatorial expression of Tcf7l2, Lef1, Gbx2, Prox1, Pou4f1, Esrrg, and Six3 transcription factor genes. …”
Publicado 2015
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36644“…The appeal of these circuits is that they intrinsically perform normalization without requiring an explicit divisive normalization. However, even in idealized simulations, we find that these circuits are very sensitive to internal noise as they accumulate error over time. …”
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36645“…Targeting expression of the D-type cyclin CYCD7;1 to the central cell and early endosperm (FWA:CYCD7;1) triggered nuclear divisions and partial ovule abortion, reducing seed number in each silique and leading to increased seed size. …”
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36646por Chawla, Daniel G., Shah, Ruchi V., Barth, Zachary K., Lee, Jessica D., Badecker, Katherine E., Naik, Anar, Brewster, Megan M., Salmon, Timothy P., Peel, Nina“…We find that although all five TTLL enzymes are expressed in the embryo and adult worm, loss of individual enzymes does not perturb microtubule function in embryonic cell divisions. Moreover, normal dye-filling, osmotic avoidance and male mating behavior indicate the presence of functional amphid cilia and male-specific neurons. …”
Publicado 2016
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36647por Yang, Jialong, Lin, Xingguang, Pan, Yun, Wang, Jinli, Chen, Pengcheng, Huang, Hongxiang, Xue, Hai-Hui, Gao, Jimin, Zhong, Xiao-Ping“…Moreover, both mTORC1 and mTORC2 contribute to Tfh and GC B cell development but may do so via distinct mechanisms. mTORC1 mainly promotes CD4 T cell proliferation to reach the cell divisions necessary for Tfh differentiation, while Rictor/mTORC2 regulates Tfh differentiation by promoting Akt activation and TCF1 expression without grossly influencing T cell proliferation. …”
Publicado 2016
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36648“…An analysis of the sequence of human blastomere divisions allowed us to postulate that the effects of zygotic determinants are eliminated as a result of cleavage, and that, thereafter, blastomeres acquire the ability of own syntheses, regulation, polarization, formation of functional contacts, and, finally, of specific differentiation. …”
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36649“…These findings suggest the need to reorient how urban injustice is considered and make efforts to acknowledge how a diversity of operational theories of change could either be divisive or could bring environmental justice and sustainability initiatives together.…”
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36650por Adewuya, Abiodun O., Ola, Bolanle A., Coker, Olurotimi A., Atilola, Olayinka, Zachariah, Mathew P., Olugbile, Olufemi, Fasawe, Adedolapo, Idris, Olajide“…METHOD: Adults (n=11 246) from the five administrative divisions of Lagos State completed questionnaires detailing suicidal ideation, socio-demographic details, common mental disorders (depression, anxiety and somatic symptoms), alcohol and psychoactive substance use disorders and disability. …”
Publicado 2016
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36651Widespread failure to complete meiosis does not impair fecundity in parthenogenetic whiptail lizardspor Newton, Aracely A., Schnittker, Robert R., Yu, Zulin, Munday, Sarah S., Baumann, Diana P., Neaves, William B., Baumann, Peter“…Production of eggs containing a full complement of chromosomes in the absence of fertilization involves genome duplication prior to the meiotic divisions. In these pseudo-tetraploid oocytes, pairing and recombination occur exclusively between identical chromosomes instead of homologs; a deviation from the normal meiotic program that maintains heterozygosity. …”
Publicado 2016
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36652por Spivey, Eric C, Jones, Stephen K, Rybarski, James R, Saifuddin, Fatema A, Finkelstein, Ilya J“…The replicative lifespan (RLS) of a cell—defined as the number of cell divisions before death—has informed our understanding of the mechanisms of cellular aging. …”
Publicado 2017
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36653“…In bacteria, for example, oscillations have been proven to control many fundamental processes, ranging from gene expression to cell divisions. In genetic circuits, oscillations originate from elemental block such as autorepressors and toggle switches, which produce robust and noise-free cycles with well defined frequency. …”
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36654por Lukies, Matthew W., Watanabe, Yoshiyuki, Tanaka, Hisashi, Takahashi, Hiroto, Ogata, Soshiro, Omura, Kayoko, Yorifuji, Shiro, Tomiyama, Noriyuki“…Total brain volume and a further seven regions were assessed, including lobar volumes, lateral divisions, and separated grey and white matter. Additive genetics and unique environment (AE) models for global brain volumes including total brain (90%), grey matter (91%) and white matter (84%) and many lobar volumes demonstrated high heritability in our study population. …”
Publicado 2017
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36655“…However, our analysis of CSOs’ ethnicness nuances research characterizing organizations as either inclusive or divisive. Moreover, local legitimacy is not based on ethnicness per se, but CSOs’ ability to skilfully interact with ethnically divided constituencies and political structures. …”
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36656“…Subsequently, neighbouring cells express neurog1 inside the placode, and apical symmetric divisions amplify the specified pool. Interestingly, pioneer cells delaminate shortly after ingression. …”
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36657IL-2 imprints human naive B cell fate towards plasma cell through ERK/ELK1-mediated BACH2 repressionpor Hipp, Nicolas, Symington, Hannah, Pastoret, Cédric, Caron, Gersende, Monvoisin, Céline, Tarte, Karin, Fest, Thierry, Delaloy, Céline“…An active regulatory region within the BACH2 super-enhancer, under ELK1 control and differentially regulated upon B-cell activation and cellular divisions, helps integrate IL-2 signal. Our study thus provides insights into the temporal regulation of BACH2 and its targets for controlling the differentiation of human naive B cells.…”
Publicado 2017
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36658por Bizzotto, Sara, Uzquiano, Ana, Dingli, Florent, Ershov, Dmitry, Houllier, Anne, Arras, Guillaume, Richards, Mark, Loew, Damarys, Minc, Nicolas, Croquelois, Alexandre, Houdusse, Anne, Francis, Fiona“…The ventricular zone (VZ) of the developing cerebral cortex is a pseudostratified epithelium that contains progenitors undergoing precisely regulated divisions at its most apical side, the ventricular lining (VL). …”
Publicado 2017
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36659por Chen, Hsin-Ying, Chang, Joseph Tung-Chieh, Chien, Kun-Yi, Lee, Yun-Shien, You, Guo-Rung, Cheng, Ann-Joy“…The four sorted cell groups exhibited distinct cell cycle distributions, asymmetric/symmetric cell divisions, and different relative expression levels of stemness markers. …”
Publicado 2018
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36660por Corbet, Cyril“…Although most of the stem cells remain under quiescence to maintain their undifferentiated state, they can also undergo cell divisions as required to regulate tissue homeostasis. …”
Publicado 2018
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