Materias dentro de su búsqueda.
Mostrando 355,761 - 355,780 Resultados de 356,398 Para Buscar '"The Establishment', tiempo de consulta: 1.70s Limitar resultados
  1. 355761
    “…Niacin appears to exert the greatest beneficial effects on the widest range of lipoprotein abnormalities, in addition to possessing an established safety profile. Moreover, niacin/statin combination therapy may provide greater benefits, as manifested through a correction of atherogenic lipid abnormalities, a slowing of atherosclerosis progression in coronaryheart disease (CHD) patients, and a reduction of residual cardiovascular risk. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Targeting Low HDL-Cholesterol to Decrease Residual Cardiovascular Risk in the Managed Care Setting
  2. 355762
    “…In this study, we aim to test the efficacy and determine the cellular mechanism of action of DR-18 in combination with immune checkpoint inhibitors (ICIs) in immunocompetent preclinical models of renal cell carcinoma (RCC), with the goal of establishing the basis for testing these combinations in early phase clinical trials. …”
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    A modified IL-18 drug in combination with CTLA-4 blockade enhances anti-tumor efficacy in preclinical models of renal cell carcinoma
  3. 355763
    “…A consensus is needed about how the diagnosis is established, to facilitate evidence‐based therapies geared toward improving outcomes.…”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Ludwig's angina and acute myocardial infarction: A case report
  4. 355764
    “…Further work is required to establish links between altered stride time variables and the risk of musculoskeletal injury.…”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Timing Differences in Stride Cycle Phases in Retired Racehorses Ridden in Rising and Two-Point Seat Positions at Trot on Turf, Artificial and Tarmac Surfaces
  5. 355765
    “…Antisense oligonucleotide (ASO) targeting SNORD14E was designed and patient-derived organoids (PDO) models in EC patients was established. A xenograft mouse and PDO model were employed to evaluate the effects of ASO targeting SNORD14E. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    A patient-derived organoid-based study identified an ASO targeting SNORD14E for endometrial cancer through reducing aberrant FOXM1 Expression and β-catenin nuclear accumulation
  6. 355766
    “…We constructed the stably expressing cell lines with shRUNX1 and RUNX1, and successfully established GEM-resistant cell line. The role of RUNX1 in GEM resistance was determined by CCK8 assay, plate colony formation assay and apoptosis analysis in vitro and in vivo. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Combination of RUNX1 inhibitor and gemcitabine mitigates chemo‐resistance in pancreatic ductal adenocarcinoma by modulating BiP/PERK/eIF2α-axis-mediated endoplasmic reticulum stress
  7. 355767
    “…Our study aims to identify screening methods for CMR based on echocardiographic data, with the goal of establishing a more practical and cheap method of screening for severity of RV dilatation in patients with asymptomatic rTOF. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Right ventricular dilatation score: a new assessment to right ventricular dilatation in adult patients with repaired tetralogy of Fallot
  8. 355768
    “…For each record, we took the level of prenatal exposure to PM(2.5) as the average concentration in the mother’s residential county during the entire gestational period, or a specific trimester (i.e., GA-specific exposure), according to well-established estimates of monthly levels across the contiguous US. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Gestational age modifies the association between exposure to fine particles and fetal death: findings from a nationwide epidemiological study in the contiguous United States
  9. 355769
    “…Increased or renewed reports of AI viruses, especially high pathogenicity H5N8 and H5N1 in birds and H5N1, H5N8, and H5N6 in humans globally, have established the need for a comprehensive review of current global AI virus surveillance data to assess the pandemic risk of AI viruses. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Reported Global Avian Influenza Detections Among Humans and Animals During 2013-2022: Comprehensive Review and Analysis of Available Surveillance Data
  10. 355770
    “…We confirmed previous findings by showing highly significant differences in rates of neurological and gastrointestinal symptoms (p < 0.0001). In addition, we established in the largest sample to date that Ehler-Danlos Syndrome (EDS) was more likely to occur among autistic females compared to non-autistic females. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Increased rates of chronic physical health conditions across all organ systems in autistic adolescents and adults
  11. 355771
    “…Of particular interest, it is well established that monoclonal therapy for one inflammatory disease may paradoxically trigger another inflammatory disease, for example TNF therapy triggering multiple sclerosis, and IL-17 therapy for psoriasis linked to inflammatory bowel disease. …”
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    OA21 Are novel anti-IL5 biologics triggering rheumatoid arthritis?
  12. 355772
    por Daurat, Jean-Luc, Ellis, Spencer
    Publicado 2023
    “…Future practice may benefit from establishing monitoring regimes for those with CKD and osteoporosis receiving denosumab, or bisphosphonates toward the lower end of permitted renal function. …”
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    OA11 Osteoporosis, denosumab, and hypocalcaemia in multimorbid renal impairment
  13. 355773
    “…Clinical and radiological features were collected and analyzed; meaningful features were combined with radiomic features to establish the clinical-radiological-radiomic (CRR) models. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    MRI-based machine learning models predict the malignant biological behavior of meningioma
  14. 355774
    “…In addition, each of the signatures BC proliferation, Hypoxia, Mast cells, and the GEX of AR, ESR1, and PGR had prognostic value, also after adjusting for established prognostic factors. Trial registration This trial was retrospectively registered in the ISRCTN database the 6th of December 2019, trial ID: https://clinicaltrials.gov/ct2/show/ISRCTN12474687. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Tamoxifen-predictive value of gene expression signatures in premenopausal breast cancer: data from the randomized SBII:2 trial
  15. 355775
    “…Median T2D evolution was 8 [2.0-12.0] years, 27.3% have an established CVD and 14% DKD. Prior therapy for T2D: 11% GLP1 receptor agonists (RA), 25.6% DPP4 inhibitors, 47.1% SGLT-2 inhibitors and 22.7% under insulin therapy. …”
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    THU283 Oral Semaglutide, Effectiveness, Safety And Tolerability In Real Life: A Short-term Retrospective Observational Study
  16. 355776
    “…A bridge-assay for InsR-aAb detection was established using recombinant human insulin receptor as bait and detector and validated using monoclonal antibodies as positive controls. …”
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    THU267 A Novel In Vitro Assay Correlates Insulin Receptor Autoantibodies To Fasting Insulin In Type B Insulin Resistance
  17. 355777
    “…To address this deficit, we established the ‘PCOS Epidemiology and Phenotype in Nigeria (Nigeria-PEP)’ study. …”
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    SAT363 The Prevalence And Phenotype Of Polycystic Ovary Syndrome (PCOS) In A Community-Based Population In Sub-Sahara Africa: The Nigeria-PEP Study
  18. 355778
    “…Importantly, a putative small molecule agonist decreased established metastatic lesions and increased the efficacy of αPD-L1 therapy. …”
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    OR05-01 Myeloid Cell Intrinsic NR0B2 Inhibits Regulatory T Cell Expansion Within The Tumor Microenvironment: Potential Novel Strategy For Breast Cancer Immunotherapy
  19. 355779
    “…The novel AR Proteolysis Targeting Chimera (PROTAC) degrader ARV-110 has shown high efficacy to prevent AR signaling in prostate cancer; however, its efficacy in PCOS is unknown. Using a well-established hyperandrogenemic mouse model of PCOS, we aim to test the hypothesis that decreasing AR protein levels with ARV-110 ameliorates androgen-mediated derangements in PCOS. …”
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    OR35-02 Novel Androgen Receptor PROTAC Degrader ARV-110 Ameliorates Androgen Mediated Renal Injury in a Mouse Model of Polycystic Ovary Syndrome
  20. 355780
    “…However, the investigation recommended by the consensus fails to establish the etiology in most cases. The difficulty to search for candidate genes increases the importance of using a hypothesis-free approach as whole exome sequencing (WES) for these children. …”
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    OR21-02 Diagnostic Yield Of A Multigene Approach In Children With Short Stature Of Unknown Cause
Herramientas de búsqueda: RSS