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  1. 355781
    “…PKCβ regulates expression of transcription factors, and its phosphorylation has been implicated in the vascular pathology in DM but a role in ischemic diabetic skeletal muscle injury has not been established. Here we assessed the role of Sp1 in BAG3 upregulation in ischemic skeletal muscle cells (HSMC), we found Sp1 is upregulated in ischemic HSMCs and overexpression of Sp1 enhanced BAG3 promoter luciferase activity while knock down of Sp1 impaired BAG3 upregulation in ischemia. …”
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    FRI625 Diabetic Ischemic Skeletal Muscle Injury Occurs Through Pkc-beta/sp1 Regulation Of Bag3 Expression
  2. 355782
    “…We have recently proposed a new method analogous to what is established for the anticoagulant warfarin, the time in target range (TTR). …”
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    THU617 Prolonged Exposure To Target Mitotane Concentrations Is Associated With Better Recurrence-free Survival In Patients With Adrenocortical Carcinoma On Adjuvant Treatment
  3. 355783
    “…Cut-offs, sensitivity, and specificity for glucose, insulin, and anthropometrics parameters were determined by AUC ROC analysis for predicting RI diagnosis, and Spearman´s correlation was established between biochemical variables and waist/height ratio and Delong test analysis. …”
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    THU251 Diagnostic Performance For Predicting Hepatic And Peripheral Tissue Insulin Resistance In Young Adult Men Using 1Hour Post Load Serum Glucose And Insulin Levels A Pilot Study
  4. 355784
    “…Multiple sclerosis risk has a well-established polygenic component, yet the genetic contribution to disease course and severity remains unclear and difficult to examine. …”
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    Genetic influences on disease course and severity, 30 years after a clinically isolated syndrome
  5. 355785
    “…The five most reported roles performed among doctors included the distribution of health education (91.4%), following up (85.9%), establishing archives (71.3%), medicine adjustment (64.7%) and treatment implementation (52.0%). …”
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    A situational analysis of human resource and non-communicable diseases management for community health workers in Chengdu, China: a cross-sectional study
  6. 355786
    “…Thus, this systematic review and aggregated data meta-analysis was conducted to establish the safety and tolerability of repeated doses with DP in IPTp. …”
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    Safety and tolerability of repeated doses of dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria in pregnancy: a systematic review and an aggregated data meta-analysis of randomized controlled trials
  7. 355787
    “…The groups were analysed with respect to age, sex and the presence of well-established risk factors for vascular disease. The study was conducted using MDCTA, where we analysed the quantitative and qualitative (morphologic) characteristics of carotid artery lesions. …”
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    Quantitative and Qualitative Characteristics of Atherosclerotic Plaques on Carotid Arteries in Patients with Antiphospholipid Syndrome: The Role of MDCT Angiography
  8. 355788
    “…BACKGROUND: As strength sports gain popularity, there is a growing need to explore the impact of sustained strength training on cardiac biventricular structure and function, an area that has received less attention compared to the well-established physiological cardiac adaptation to endurance training. …”
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    Effects of a 20-Week High-Intensity Strength Training Program on Muscle Strength Gain and Cardiac Adaptation in Untrained Men: Preliminary Results of a Prospective Longitudinal Study
  9. 355789
    “…Hence, it is essential to establish chemotherapeutic regimens based on SBA characteristics. …”
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    Clinical significance of programmed cell death-ligand expression in small bowel adenocarcinoma is determined by the tumor microenvironment
  10. 355790
    “…In vivo experiments were verified by establishing a subcutaneous transplantation tumor model in nude mice, observing the size and volume of tumors in vivo in nude mice, and obtaining fresh tissues for subsequent experiments. …”
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    Transcription factor LHX9 (LIM Homeobox 9) enhances pyruvate kinase PKM2 activity to induce glycolytic metabolic reprogramming in cancer stem cells, promoting gastric cancer progression
  11. 355791
    “…In conclusion, the expression levels of miR-375 and miR-200c family differed significantly during disease process, and these miRNAs establishes a link between T. forsythia and development of periodontitis genesis, offering new insights regarding the pathobiology of this bacterium.…”
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    Unique miRomics Expression Profiles in Tannerella forsythia-Infected Mandibles during Periodontitis Using Machine Learning
  12. 355792
    “…For agents without established CLSI breakpoints, only MIC(50), MIC(90) and MIC ranges were reported. …”
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    2761. Activity of Cefiderocol and Comparator Agents Against Achromobacter and Burkholderia Isolates, Collected During 2020-2022 as Part of SENTRY Antimicrobial Surveillance Program
  13. 355793
    “…The limited options, routes of administration, and toxicity of antifungals with established efficacy against Tm calls for assessment of efficacy for additional antifungals against Tm. …”
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    2108. In-vitro Activity of Five Novel Anti-Fungal Compounds Against Thirty-Two Strains of Talaromyces marneffei
  14. 355794
    “…For this study, the LOAEL established by the US Environmental Protection Agency of 50 mg/kg body weight (BW)/day of BPA was used. …”
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    Bisphenol-A disturbs hormonal levels and testis mitochondrial activity, reducing male fertility
  15. 355795
    “…The primary objective was to establish the IAC prevalence. The secondary objective was to explore whether sBDG and pBDG could be used to diagnose IAC. …”
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    Combination of serum and peritoneal 1.3-beta-d-glucan can rule out intra-abdominal candidiasis in surgical critically ill patients: a multicenter prospective study
  16. 355796
    “…MR investigations with a high rf-pulse density lasting below a minute can establish volumes of several cubic millimeters with temperature increases high enough to start cell destruction. …”
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    Finite volume analysis of temperature effects induced by active MRI implants: 2. Defects on active MRI implants causing hot spots
  17. 355797
    por Coleman, R, Bell, RM
    Publicado 1978
    “…An exact correspondence between mannose- 6-phosphate activity and membrane permeability to EDTA has been established (4). The latency of mannose-6-phosphatase activity provides a quantitative index of microsomal integrity (4.) …”
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    Evidence that biosynthesis of phosphatidylethanolamine, phosphatidylcholine, and triacylglycerol occurs on the cytoplasmic side of microsomal vesicles
  18. 355798
    “…It is somewhat remarkable that all of our dogs showed hydronephrosis after the first operation. The results of establishing a urinary fistula differed in the two cases in which it was tried: The fluid did not re-form in Dog 3 even when sodium sulphate was injected: whereas in Dog 4, a very abundant quantity of fluid reaccumulated spontaneously; but it differed notably in composition from the original fluid, having more the character of a purulent inflammatory exudate. …”
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    EXPERIMENTAL ATRESIA OF THE URETER
  19. 355799
    por Zinsser, Hans
    Publicado 1913
    “…For as the bacteria diminish and the sensitizer increases, a changed proportion between them is established which, finally, as experiment has shown, results in a failure of anaphylatoxin production. …”
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    ON ANAPHYLATOXINS AND ENDOTOXINS OF THE TYPHOID BACILLUS
  20. 355800
    por Dochez, A. R., Avery, O. T.
    Publicado 1915
    “…The suggestion is made that strictly parasitic races of microorganisms are pure lines and have established themselves as parasites during a period of high racial susceptibility.…”
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    VARIETIES OF PNEUMOCOCCUS AND THEIR RELATION TO LOBAR PNEUMONIA
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