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  1. 355861
    por Hickman, Matthew, Dillon, John F, Elliott, Lawrie, De Angelis, Daniela, Vickerman, Peter, Foster, Graham, Donnan, Peter, Eriksen, Ann, Flowers, Paul, Goldberg, David, Hollingworth, William, Ijaz, Samreen, Liddell, David, Mandal, Sema, Martin, Natasha, Beer, Lewis J Z, Drysdale, Kate, Fraser, Hannah, Glass, Rachel, Graham, Lesley, Gunson, Rory N, Hamilton, Emma, Harris, Helen, Harris, Magdalena, Harris, Ross, Heinsbroek, Ellen, Hope, Vivian, Horwood, Jeremy, Inglis, Sarah Karen, Innes, Hamish, Lane, Athene, Meadows, Jade, McAuley, Andrew, Metcalfe, Chris, Migchelsen, Stephanie, Murray, Alex, Myring, Gareth, Palmateer, Norah E, Presanis, Anne, Radley, Andrew, Ramsay, Mary, Samartsidis, Pantelis, Simmons, Ruth, Sinka, Katy, Vojt, Gabriele, Ward, Zoe, Whiteley, David, Yeung, Alan, Hutchinson, Sharon J
    Publicado 2019
    “…METHODS AND ANALYSIS: We plan to establish a natural experiment with Tayside, Scotland, as a single intervention site where HCV care pathways are being expanded (including specialist drug treatment clinics, needle and syringe programmes (NSPs), pharmacies and prison) and HCV treatment for PWID is being rapidly scaled-up. …”
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    Evaluating the population impact of hepatitis C direct acting antiviral treatment as prevention for people who inject drugs (EPIToPe) – a natural experiment (protocol)
  2. 355862
    “…IMPORTANCE: The histologic evolution of the full spectrum of nonalcoholic fatty liver disease (NAFLD) and factors associated with progression or regression remain to be definitively established. OBJECTIVE: To evaluate the histologic evolution of NAFLD and the factors associated with changes in disease severity over time. …”
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    Association of Histologic Disease Activity With Progression of Nonalcoholic Fatty Liver Disease
  3. 355863
    por Zhang, Hua, Lan, Xiang, Peng, Bing, Li, Bo
    Publicado 2019
    “…Although the safety and feasibility of TLPD have been established, few studies have compared it with open pancreaticoduodenectomy (OPD) with regard to perioperative and oncological outcomes. …”
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    Is total laparoscopic pancreaticoduodenectomy superior to open procedure? A meta-analysis
  4. 355864
    “…This section is about certain safety aspects of dialysis, not seeking to replace well-established local protocols, but focussing on just a few where we thought some national-level guidance would be useful. 8. …”
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    Renal Association Clinical Practice Guideline on Haemodialysis
  5. 355865
    “…DISCUSSION/SIGNIFICANCE OF IMPACT: The training program established a pool of patient navigators which will contribute towards reducing the cancer health disparity in the Appalachian region of Pennsylvania. …”
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    2285 Patient navigation training: Community-engaged workforce development
  6. 355866
    “…Patient frailty status was measured using a modified version of the Canadian Health and Aging frailty index (FI), which generates a score (range 0–1) by dividing the number of deficits present by the number of deficits measured. Established categories for FI scores are: non frail ≤0.10, vulnerable 0.10–0.21, frail 0.22–0.45, and very frail >0.45. …”
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    2156: A confounder assessment of patient frailty in the relationship between antidiabetic medication and heart failure
  7. 355867
    “…Our next steps involve establishing a prospective study to measure the effects of preoperative education on patient satisfaction with their procedure, post-operative communications, and discharge by noon rates. …”
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    3228 POET: A perioperative educational tool as an adjunct to enhanced recovery after surgery in patients undergoing minimally invasive gynecologic oncology surgery
  8. 355868
    “…METHODS/STUDY POPULATION: Two hundred participants completed a 90-Day TLFB interview, wherein the maximum number of drinks in a day established the participant’s binge level status as a Non-Binger (N = 37), Binge Level 1 (N = 96), Binge Level 2 (N = 44), or Binge Level 3 (N = 22). …”
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    3294 HIGH INTENSITY BINGE DRINKING AND STIMULATING EFFECTS IN HUMAN LABORATORY STUDIES OF ALCOHOL SELF-ADMINISTRATION
  9. 355869
    “…Due to the under-representation of Hispanic/Latino men but most importantly women in s studying the pharmacology of sublingual Buprenorphine, and considering the well-established gender difference of the principal enzyme (CYP 3A4) responsible for the pharmacology of Buprenorphine, we are proposing a pilot study of the pharmacology of sublingual Buprenorphine in Hispanic/Latino volunteers living in Puerto Rico with equal number of male and female patients. …”
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    2198: Gender differences in the pharmacology of buprenorphine sublingual tablets in Hispanics/Latinos: An underrepresented population
  10. 355870
    “…There was a mix of participants ranging from those with established community-academic partnerships to others who were new to community-engaged research and in early stages of forming partnerships. …”
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    3573 Critical Barriers to Effective Community-Academic Research Partnerships and Potential Solutions
  11. 355871
    por Genkins, Julian, Lasko, Thomas A.
    Publicado 2018
    “…Being able to answer only the question of how a patient will respond—will they move toward or away from our therapeutic goal—is as good as existing prediction methods. It is well established in the literature that, by almost any metric, ~50% of hemodynamically unstable patients respond to a fluid challenge. …”
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    2412: Predicting response to hemodynamic interventions in the ICU using recurrent neural networks
  12. 355872
    “…The P.a. strains initially infecting the CF lung have a nonmucoid colony morphology, whereas, once chronic infection is established, these bacteria mutate leading to the emergence of mucoid P.a. variants with heightened resistance to both antibiotics and host immunity. …”
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    2301 Mucoidal pseudomonas aeruginosa infection is associated with regional inflammation in the cystic fibrosis lung
  13. 355873
    “…The CTSA-funded Pilot Project aims to: (1) Engage CBN seniors and stakeholders in priority-setting, joint protocol development, research conduct, analysis, and dissemination; (2) Characterize the health status of the CBN seniors using validated measures; (3) Establish database infrastructure for current and future research; (4) Understand how health and senior activities information can be used to create programs to improve senior health. …”
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    2324 A community-academic partnership to understand the correlates of successful aging in place (year 2)
  14. 355874
    “…At the same time, (SBOS) mice in the drug group and (CG) mice in the positive control group were given intraabdominal injection of CTX (200 mg/kg/d).The immunosuppressive mouse model (CY) was established after 72 h in the model group and the positive control group (CG) was given intragastric administration of levamisole hydrochloric acid (LMS) for 3 days, with the data of 80ug/kg/d after injection of CTX (for actually 72 h). …”
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    Impacts of functional oligosaccharide on intestinal immune modulation in immunosuppressive mice
  15. 355875
    “…LARGE SCALE DATA: N/A LIMITATIONS, REASONS FOR CAUTION: Although not noticeable in this study, we cannot exclude that if an optimized culture method ensuring complete spermatogenesis in human testicular fragments is established, differences in functional or spermatogenic efficiency between fresh and cryopreserved tissue might be found. …”
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    Assessment of fresh and cryopreserved testicular tissues from (pre)pubertal boys during organ culture as a strategy for in vitro spermatogenesis
  16. 355876
    “…THE TRANSLATIONAL POTENTIAL OF THIS ARTICLE: To date, no consensus for prosthesis selection in TKA has been established. This study found significant differences in joint flexion/extension angle and internal/external rotation during gait post-TKA surgery in medial knee osteoarthritis patients who received different prostheses. …”
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    Does mobile-bearing have better flexion and axial rotation than fixed-bearing in total knee arthroplasty? A randomised controlled study based on gait
  17. 355877
    “…The Universitair Ziekenhuis Brussel (UZ Brussel) and the Center for Medical Genetics have received several educational grants from IBSA, Ferring, MSD and Merck for establishing the database for follow-up research and organizing the data collection.…”
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    Growth and other health outcomes of 2-year-old singletons born after IVM versus controlled ovarian stimulation in mothers with polycystic ovary syndrome
  18. 355878
    “…The governments and policy-makers should stand with universities by supporting and establishing matured policies which helps universities to have mental health service centers. …”
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    Depressive Symptoms among Haramaya University Students in Ethiopia: A Cross-Sectional Study
  19. 355879
    “…Longer-term follow-up studies of women of more advanced age are warranted to establish whether women with POI are truly at increased risk of developing CVD events later in life. …”
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    The cardiovascular risk profile of middle age women previously diagnosed with premature ovarian insufficiency: A case-control study
  20. 355880
    “…However, as these databases are typically not established for the primary purpose of performing research, they should be evaluated prior to utilization for research both to inform the study design and to determine the extent to which key study variables, such as patient characteristics or therapies provided, are accurately documented in the database. …”
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    The Canadian Assisted Reproductive Technologies Register (CARTR) Plus database: a validation study
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