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  1. 355921
    “…A multidisciplinary panel of experts was first established, based on the clinical and scientific sharing of the thematic area of present recommendations. …”
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    Recommendations for neonatologists and pediatricians working in first level birthing centers on the first communication of genetic disease and malformation syndrome diagnosis: consensus issued by 6 Italian scientific societies and 4 parents’ associations
  2. 355922
    “…We found no trial evidence comparing ginseng to other agents with a more established role in treating erectile dysfunction, such as phosphodiesterase‐5 inhibitors.…”
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    Ginseng for erectile dysfunction
  3. 355923
    “…Construct validity was established by comparing correlation patterns of the MCS(VR) and PCS(VR) with measures of physical and mental health. …”
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    Translation and adaptation of the German version of the Veterans Rand—36/12 Item Health Survey
  4. 355924
    “…While serum potassium disorders are common and associated with adverse outcomes, the exact recommended potassium level for patients with HF are not entirely established. We aimed to investigate the prognostic role of potassium levels on a cohort of patients with symptomatic chronic HF. …”
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    Serum potassium levels provide prognostic information in symptomatic heart failure beyond traditional clinical variables
  5. 355925
    “…To ensure high-quality results are delivered to guide clinical decision making and the public health response, as well as characterize the response to interventions, it is essential to establish the accuracy of COVID-19 case definitions derived from administrative data to identify infections and hospitalizations. …”
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    Accuracy of Computable Phenotyping Approaches for SARS-CoV-2 Infection and COVID-19 Hospitalizations from the Electronic Health Record
  6. 355926
    “…METHODS: Consecutive patients with established CKD and estimated glomerular filtration rate (eGFR) < 59 ml/min/1.73 m(2) (n = 276) were compared to age/sex matched patients with eGFR ≥ 60 ml/min/1.73 m(2) (n = 242) and healthy controls (n = 38). …”
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    Cardiac biomarkers in chronic kidney disease are independently associated with myocardial edema and diffuse fibrosis by cardiovascular magnetic resonance
  7. 355927
    “…Endocannabinoids have been measured in follicular fluid (FF) obtained during oocyte retrieval and are implicated in controlling folliculogenesis. It has been established that in the placenta, PCs disrupt endocannabinoid homeostasis via impairment of the synthetic and degrading enzymes, leading to a net increase of endocannabinoid levels. …”
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    Cannabis alters epigenetic integrity and endocannabinoid signalling in the human follicular niche
  8. 355928
    “…Ongoing efforts shall establish clinically usable protocols and SUV thresholds for decision-making based on quantitative SPECT.…”
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    ROC study and SUV threshold using quantitative multi-modal SPECT for bone imaging
  9. 355929
    “…Amounts were evaluated as a percentage of the quantity recommended by established dietary guidelines. RESULTS: Increased time availability was associated with increases in the percentage of home-cooked meals and servings of fruits/vegetables and decreased sodium consumption. …”
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    Association of Funding and Meal Preparation Time With Nutritional Quality of Meals of Supplemental Nutritional Assistance Program Recipients
  10. 355930
    “…OBJECTIVE: To examine the prognostic accuracy of baseline fluorine 18 ((18)F)–flortaucipir and [(18)F]RO948 (tau) PET in individuals across the Alzheimer disease (AD) clinical spectrum and to perform a head-to-head comparison against established magnetic resonance imaging (MRI) and amyloid PET markers. …”
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    Accuracy of Tau Positron Emission Tomography as a Prognostic Marker in Preclinical and Prodromal Alzheimer Disease: A Head-to-Head Comparison Against Amyloid Positron Emission Tomography and Magnetic Resonance Imaging
  11. 355931
    por Schrijver, Lieske H., Antoniou, Antonis C., Olsson, Håkan, Mooij, Thea M., Roos-Blom, Marie-José, Azarang, Leyla, Adlard, Julian, Ahmed, Munaza, Barrowdale, Daniel, Davidson, Rosemarie, Donaldson, Alan, Eeles, Ros, Evans, D. Gareth, Frost, Debra, Henderson, Alex, Izatt, Louise, Ong, Kai-Ren, Bonadona, Valérie, Coupier, Isabelle, Faivre, Laurence, Fricker, Jean-Pierre, Gesta, Paul, van Engelen, Klaartje, Jager, Agnes, Menko, Fred H., Mourits, Marian J.E., Singer, Christian F., Tan, Yen Y., Foretova, Lenka, Navratilova, Marie, Schmutzler, Rita K., Ellberg, Carolina, Gerdes, Anne-Marie, Caldes, Trinidad, Simard, Jacques, Olah, Edith, Jakubowska, Anna, Rantala, Johanna, Osorio, Ana, Hopper, John L., Phillips, Kelly-Anne, Milne, Roger L., Beth Terry, Mary, Noguès, Catherine, Engel, Christoph, Kast, Karin, Goldgar, David E., van Leeuwen, Flora E., Easton, Douglas F., Andrieu, Nadine, Rookus, Matti A.
    Publicado 2021
    “…Although the effects of using oral contraceptives in the general population are well established (approximately 50% risk reduction in ovarian cancer), the estimated risk reduction in mutation carriers is much less precise because of potential bias and small sample sizes. …”
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    Oral contraceptive use and ovarian cancer risk for BRCA1/2 mutation carriers: an international cohort study
  12. 355932
    “…The Medical College of Wisconsin established the international SECURE-SCD Registry to collect data on pediatric and adult COVID-19 infections in individuals living with SCD. …”
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    Hospitalization and Case Fatality in Individuals with Sickle Cell Disease and COVID-19 Infection
  13. 355933
    por Sandman, Karen E., Bell, Timothy J.
    Publicado 2020
    “…Six core publications were used to establish keywords and for bibliographic and prospective citation searches to identify additional relevant publications relating to patient preference and patient/caregiver-reported outcomes regarding cancer treatment administration settings. …”
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    Patient-Focused Benefits of at-Home Versus in-Clinic Administration of Cancer Therapy: New Considerations for the COVID-19 Era
  14. 355934
    “…Results: Univariate followed by multivariable regression modeling in the 2785 patient overall cohort established a novel role for RI, and independent roles for age, BMI, and maximum DD, in predicting severity of illness. …”
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    Admission Rothman Index, Aspirin, and Intermediate Dose Anticoagulation Effects on Outcomes in COVID-19: A Multi-Site Propensity Matched Analysis
  15. 355935
    “…However, the optimal dose of anticoagulant for patients with COVID-19 is unknown. Establishing the optimal thromboprophylaxis strategy and determining the role of biomarkers for patient risk stratification may help to improve outcomes in COVID-19. …”
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    The Role of D-Dimer for Optimal Thromboprophylaxis Strategy in Patients with COVID-19
  16. 355936
    “…Introduction The outcomes related to different anticoagulation doses in Coronavirus disease 2019 (COVID-19) patients are not well established. COVID-19 is associated with increased thrombotic events and early coagulopathy as reported by a large New York City health system. …”
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    Outcomes in COVID-19 Patients on Treatment Dose Anti-Coagulation Compared to Prophylactic Dose Anti-Coagulation
  17. 355937
    “…BMI was shown to be an important risk factor with other factors less so, but no rank order was established. This work also offers, for the first time, a neural network computer model to predict the overall increase or decreased risk of cancer for individual patients, which is 98.6% accurate. …”
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    Statistical Meta-Analysis of Risk Factors for Endometrial Cancer and Development of a Risk Prediction Model Using an Artificial Neural Network Algorithm
  18. 355938
    “…Policy recommendations place emphasis on the use of medication‐assisted treatments (MAT) as a front‐line defense among correctional populations, because its efficacy and effectiveness has been well‐established in other contexts.  Despite this, criminal justice agencies have been reluctant or slow to do so. …”
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    PROTOCOL: Opioid‐specific medication‐assisted therapy and its impact on criminal justice and overdose outcomes
  19. 355939
    “…Due to unavailability of parental DNA, we have not assessed the frequency of de novo or maternally inherited dominant variants and could not determine the parental origin of the mutations to establish in all cases that the mutations are present on both alleles. …”
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    Exome sequencing reveals variants in known and novel candidate genes for severe sperm motility disorders
  20. 355940
    “…OBJECTIVE: To examine the prevalence, odds, and population attributable risk (PAR) percentage for established and novel risk factors for ICH, stratified by ICH location and racial/ethnic group. …”
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    Ethnic and Racial Variation in Intracerebral Hemorrhage Risk Factors and Risk Factor Burden
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