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356121por Nguyen, Geoffrey C, Targownik, Laura E, Singh, Harminder, Benchimol, Eric I, Bitton, Alain, Murthy, Sanjay K, Bernstein, Charles N, Lee, Kate, Cooke-Lauder, Jane, Kaplan, Gilaad G“…However, research is necessary to establish the IBD-attributable cost to the healthcare system and the indirect cost to society.…”
Publicado 2019
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356122por Yarmolinsky, James, Relton, Caroline L., Lophatananon, Artitaya, Muir, Kenneth, Menon, Usha, Gentry-Maharaj, Aleksandra, Walther, Axel, Zheng, Jie, Fasching, Peter, Zheng, Wei, Yin Ling, Woo, Park, Sue K., Kim, Byoung-Gie, Choi, Ji-Yeob, Park, Boyoung, Davey Smith, George, Martin, Richard M., Lewis, Sarah J.“…A Bonferroni-corrected P value threshold was used to establish strong evidence (P < 0.0042) and suggestive evidence (0.0042 < P < 0.05) for associations. …”
Publicado 2019
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356123por Maher, Geoffrey J, Bernkopf, Marie, Koelling, Nils, Wilkie, Andrew O M, Meistrich, Marvin L, Goriely, Anne“…DNA extracted from semen samples was analysed using a previously established highly sensitive assay to identify mutations at positions c.752–755 of FGFR2. …”
Publicado 2019
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356124“…Review of literature outside of this context, especially in regards of specifically lung malignancy is limited – so a consistent established link may be less apparent. Of the limited studies, interestingly there have been reports of patients with biopsy proven lung malignancy and raised MPO/PR3, with levels normalising following treatment of the underlying lesion. …”
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356125“…Our patient had hypothyroidism, which is known to potentiate statin induced myopathy, however, strong association with IMNM is not established. Around 80% patients with anti HMGCR associated myositis have prior statin exposure, however, a subgroup of patients, especially among Asians, can have anti-HMGCR antibody and myositis even without statin exposure. …”
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356126“…Accelerated atherosclerosis is common in primary vasculitides. Despite establishing the diagnosis of LVV by ultrasound in this case, the sensitivity for this in the common femoral artery is < 17%, and PET-CT is preferred. …”
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356127“…The emergence of new myositis specific antibodies (MSAs) and their relation to specific disease phenotypes may be useful in establishing a new clinical-serological diagnostic criteria for different disease presentations and thus help to determine management and prognosis. …”
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356128“…Temporal artery biopsy reported findings consistent with GCA. He was re-established on prednisolone 60mg however intermittent headache recurred and CRP gradually increased. …”
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356129“…Knowledge of the muscles innervations may help to establish a neurogenic aetiology where muscles are solely affected. …”
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356130“…However, the benefit of using EHL over SHL rFVIII products for prophylactic therapy has not been universally established, and there is no recommendation for one product over the other. …”
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356131“…Methods: Neurotoxin 6-hydroxydopamine (6-OHDA) was injected into the right medial forebrain bundle (MFB) of the rats to establish the semi-lateral cerebral damage PD model. …”
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356132“…One tailed ANOVA followed by Dunnett’s post-hoc test was used to establish significance. All animal experiments were conducted as described in approved IACUC protocols. …”
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356133por Eckardt, Patricia, Kovner, Christine, Hammer, Marilyn, Barton-Burke, Margaret, McCabe, Margaret, Cohn, Elizabeth, Marino, Marie, Behrens, Liza“…OBJECTIVES/SPECIFIC AIMS: The proposed pilot study seek to enhance the network of CTSAs at Rockefeller University, NYU, ISMMS, and other community members to support translational workforce development of clinical research nurses and establish a standardized nurse-specific training curriculum in GCP for use within the CTSA network, in other research centers, and in nursing school curricula. …”
Publicado 2018
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356134por Croisant, Sharon A., Anthony, Amber L., Prochaska, John, Singleton, Chantele, Kotarba, Joseph A.“…The following are several key principles shared by both programs: (1) The importance of creative, applicable, and inclusive mission statements: (a) REACH seeks to facilitate communication, collaborative research, and service efforts between UTMB and Institute for Translational Sciences investigators and Galveston County community leaders; (b) The SCI Café hosts interactive dialogs that serve as a medium for priming, organizing, communicating and strategizing among the individuals involved in team science via community-based research projects. (2) Increasing scientific and health literacy: (a) REACH seeks to increase literacy through both short-term and long-term interactions; (b) The SCI Café focuses on short-term yet intensive interaction through conversations among researchers, clinicians, and the public. (3) Sharing timely scientific public health information with the community: (a) REACH seeks information from community leaders on relevant topics; (b) The SCI Café can mobilize quickly to respond to timely topics by direct communication with a wide range of stakeholders, academic as well as community based. (4) Sharing leadership with the community: (a) REACH establishes formal relationships with 23 UTMB units and 39 broad-based, high impact Galveston County organizations. …”
Publicado 2018
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356135por Dufresne, Jaimie, Bowden, Pete, Thavarajah, Thanusi, Florentinus-Mefailoski, Angelique, Chen, Zhuo Zhen, Tucholska, Monika, Norzin, Tenzin, Ho, Margaret Truc, Phan, Morla, Mohamed, Nargiz, Ravandi, Amir, Stanton, Eric, Slutsky, Arthur S., dos Santos, Claudia C., Romaschin, Alexander, Marshall, John C., Addison, Christina, Malone, Shawn, Heyland, Daren, Scheltens, Philip, Killestein, Joep, Teunissen, Charlotte, Diamandis, Eleftherios P., Siu, K. W. M., Marshall, John G.“…The protein gene symbols with large Chi Square values were significantly enriched in proteins that showed a complex set of previously established functional and structural relationships by STRING analysis. …”
Publicado 2019
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356136por Harpelunde Poulsen, K, Nielsen, J E, Frederiksen, H, Melau, C, Juul Hare, K, Langhoff Thuesen, L, Perlman, S, Lundvall, L, Mitchell, R T, Juul, A, Rajpert-De Meyts, E, Jørgensen, A“…STUDY DESIGN, SIZE, DURATION: FGF signalling was manipulated in human fetal gonads in an established ex vivo culture model by treatments with recombinant FGF9 (25 ng/ml) and the tyrosine kinase inhibitor SU5402 (10 μM) that was used to inhibit FGFR signalling. …”
Publicado 2019
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356137por Gunning, Marlise N, Sir Petermann, Teresa, Crisosto, Nicolas, van Rijn, Bas B, de Wilde, Marlieke A, Christ, Jacob P, Uiterwaal, C S P M, de Jager, Wilco, Eijkemans, Marinus J C, Kunselman, Allen R, Legro, Richard S, Fauser, Bart C J M“…BACKGROUND: Women diagnosed with polycystic ovary syndrome (PCOS) suffer from an unfavorable cardiometabolic risk profile, which is already established by child-bearing age. OBJECTIVE AND RATIONALE: The aim of this systematic review along with an individual participant data meta-analysis is to evaluate whether cardiometabolic features in the offspring (females and males aged 1–18 years) of women with PCOS (OPCOS) are less favorable compared to the offspring of healthy controls. …”
Publicado 2020
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356138por Wei, Xing, Lin, Yaping, Zhao, Dongfeng, Xiao, Xiaojuan, Chen, Qiao, Chen, Siyi, Peng, Yan“…Rats in the modeling group were injected 2% streptozotocin (STZ) and fed with high-glucose and high-fat diet for 8 weeks in order to establish DGP rat model. After modeling, 30 successfully modeled rats were randomly selected and separated into diabetic gastroparesis group (DGP, 10), GDP rats with electroacupuncture group (EA, 10), and GDP rats with metoclopramide group (MP, 10). …”
Publicado 2020
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356139“…LDV is a highly cytocidal virus that invariably establishes a life-long, viremic, persistence in mice, in spite of normal anti-viral immune responses. …”
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356140por Veeram Reddy, Surendranath R., Arar, Yousef, Zahr, Riad Abou, Gooty, Vasu, Hernandez, Jennifer, Potersnak, Amanda, Douglas, Phillip, Blair, Zachary, Greer, Joshua S., Roujol, Sébastien, Forte, Mari Nieves Velasco, Greil, Gerald, Nugent, Alan W., Hussain, Tarique“…This pilot study’s objective is to establish feasibility of right (RHC) and left heart catheterization (LHC) during invasive CMR (iCMR) procedures at our institution in the CHD population. …”
Publicado 2020
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