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1921por Murphy, Amy, McQueen, Matthew B, Su, Jessica, Kraft, Peter, Lazarus, Ross, Laird, Nan M, Lange, Christoph, Van Steen, Kristel“…We compare the results of our screening technique across univariate and multivariate family-based association tests. From our analyses, we observe that the screening technique, applied to different settings, is fairly consistent in identifying optimal markers for testing. …”
Publicado 2005
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1922por Wapenaar, Martin C., Monsuur, Alienke J., Poell, Jos, van ‘t Slot, Ruben, Meijer, Jos W. R., Meijer, Gerrit A., Mulder, Chris J., Mearin, Maria Luisa, Wijmenga, Cisca“…The gene family of serine protease inhibitors of the Kazal type (SPINK) are functional and positional candidate genes for celiac disease (CD). …”
Publicado 2007
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1923“…Several of these scaffolding proteins important for synaptic and cellular junctions belong to the large family of membrane-associated guanylate kinases (MAGUK). …”
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1924
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1925“…A study of Burkitt's lymphoma (BL) in Papua New Guinea for the years 1958-87 revealed four instances of familial BL. Incident cases occurred within 1 year of each other in the four families. …”
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1926“…The prevalence of undescended testis (UDT) did not seem to be higher in familial than in sporadic TC (8.2% in familial TC and 13.3% in sporadic cases). …”
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1927
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1928por Mohammed, S. N., Smith, P., Hodgson, S. V., Fentiman, I. S., Miles, D. W., Barnes, D. M., Millis, R. R., Rubens, R. D.“…There was a highly significant survival advantage for patients with a family history (chi2 = 22.4, P < 0.001). Five- and 10-year survival rates were 92% and 87% for those with a family history compared with 70% and 54% for those in the control group. …”
Publicado 1998
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1929“…METHODS: Presentation of a family with two siblings with Gaucher's disease. RESULTS: In a six-member family, the first son suffers from schizophrenia, while the third and fourth sons suffer from the Gaucher's disease (type 1 non-neuronopathic). …”
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1930“…BACKGROUND: Family-based association tests are important tools for investigating genetic risk factors of complex diseases. …”
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1931
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1932por Lynch, H. T., Marcus, J. N., Weisenburger, D. D., Watson, P., Fitzsimmons, M. L., Grierson, H., Smith, D. M., Lynch, J., Purtilo, D.“…We have studied a remarkable family with seven cases of malignant lymphoma extending through three generations wherein five sisters and their mother had histopathologically documented non-Hodgkin's lymphoma, while a granddaughter had Hodgkin's disease. …”
Publicado 1989
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1933por Oelkers, Karsten, Goffard, Nicolas, Weiller, Georg F, Gresshoff, Peter M, Mathesius, Ulrike, Frickey, Tancred“…RESULTS: We identified 114 new members of the CLE protein family from various plant species, as well as five protein sequences containing multiple CLE domains. …”
Publicado 2008
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1934“…BACKGROUND: A relationship between corneal arcus and atherosclerosis has long been suspected but is controversial. The homozygous familial hypercholesterolemia patients in this study present a unique opportunity to assess this issue. …”
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1935Publicado 1992“…Most of these members of the kinesin family are implicated in mechanisms of mitosis or meiosis. …”
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1936
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1937“…A prospective population-based study recorded family trees of 77 colorectal cancer patients younger than 50 years of age. …”
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1938
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1939“…Desmoids are poorly-understood, locally aggressive, non-metastasizing fibromatoses that occur with disproportionate frequency in patients with familial adenomatous polyposis (FAP). Their nature is controversial with arguments for and against a neoplastic origin. …”
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1940