“…The patient endorsed weight loss, hot flashes, anxiousness, tremors, and palpitations. She denied gastrointestinal symptoms or visual changes. …”
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“…At 18 years, she used OCPs for few months, and used plan B, after which her menses stopped. She had hot flashes and sweating. She was placed on progesterone, but never had withdrawal bleeding. …”
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“…Decreased feedback of testosterone to the hypothalamus has been described during antiandrogen therapy for prostate cancer, as the cause of hot flashes and nausea. Our patient did not have low androgen levels; however, it is possible that drastic fluctuations in androgens, caused "relative hypogonadal" status resulting in his symptomatology. …”
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“…Patients experienced hot flashes (5), arrhythmias (4), hypertension (4), abdominal pain and nausea (2), headaches (1) and asymptomatic (1). …”
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“…Background: NK3 antagonism is a clinically validated mechanism of action for treating menopausal vasomotor symptoms (“hot flashes”). In men, reductions of LH and T are sensitive pharmacodynamic markers of central NK3 antagonism, due to the known inhibitory effect of NK3 antagonists on GnRH pulsatility. …”
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“…Full-field ERG PhNR were recorded using red (640 nm) flashes at 1 cd.s/m(2), on blue (470 nm) rod saturating background. …”
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“…Self-reported (Pre/Post Therapy) estrogen deficiency symptoms such as hot flashes, night sweats, vaginal dryness, joint pain, and sleep disturbances were significantly improved post T+AI therapy. …”
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“…Subjectively, patient reports improvement of her hot flashes, insomnia and anxiety. CONCLUSION: This case emphasizes the importance of surveillance for a lipid poor adrenal nodule. …”
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“…Fifteen patients (36%) in the ST group could not see the flashes of the laser, compared to 8 patients (19%) in the RB group (P = 0.087). …”
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“…No blood and digestive toxicity were observed in the ADT group. 33 cases (52.4%) and 48 (53.3%) of the two groups had symptoms of afternoon hot flashes and fatigue, (P = 0.961). CONCLUSION: Docetaxel chemotherapy combined with endocrine therapy could be one of effective treatments for delaying castration resistance of HVD-mHSPC, which could prolong PFS effectively and obtain a higher PSA response rate, high safety under close monitoring, and controllable adverse reactions.…”
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“…No statistically significant differences were observed in the frequencies of CYP2D6 phenotypes between the two arms (P = 0.24), nor the incidence of tamoxifen-induced hot flashes (P = 0.109). Poor metabolizers (PMs) tended to display shorter DFS than intermediate metabolizers (IMs) and normal metabolizers (NMs) combined (adjusted HR = 2.34, 95% CI = 0.84–6.55, P = 0.104). …”
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“…The toxicities of androgen deprivation have been well described, with a number of potential adverse effects on quality of life, including sexual dysfunction, hot flashes, fatigue, anemia, decreased bone density and muscle mass, altered blood lipid profile, depression, cognitive dysfunction, and worsening of the metabolic syndrome with effects on glucose metabolism and cardiovascular morbidity. …”
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“…METHODS: This double-blind Phase 3 study randomized women aged ≥40–65 years with moderate-to-severe VMS associated with menopause (average of ≥7 hot flashes/day) to once-daily placebo or fezolinetant 30mg or 45mg for 12 weeks. …”
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“…In addition to menopause-related estradiol (E2) decline, sleep fragmentation (wake episodes interrupting sleep) due to hot flashes, without a reduction in total sleep time, is common. …”
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“…The animal model successfully achieved a significant decrease in the E2, FSH, and LH levels in rats, and could cause the rats to have rising body surface temperature similar to hot flashes in the perimenopausal period. The intervention with E2 and ICR could effectively relieve such “perimenopausal symptoms”, and ICR had no obvious effect on the serum sex hormone level in rats.…”
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“…url=https%3A%2F%2Furldefense.proofpoint.com%2Fv2%2Furl%3Fu%3Dhttp-3A__iopscience.iop.org_article_10.1088_2041-2D8205_811_2_L20_pdf%26d%3DDwMFaQ%26c%3DeuGZstcaTDllvimEN8b7jXrwqOf-v5A_CdpgnVfiiMM%26r%3DzNsfNhEFLzLXS0DuD49A9nDeSBljjfthw9lp47yKyUs%26m%3D8hJbZmFsZIrQ4nRxD7J-rVJDNj6iLbPv3aiDTdhhjLA%26s%3Dkzc8XNqd8iP538FpOLTr2Jllp_97crSiFTogQbgY-j4%26e%3D&amp;data=04%7C01%7Cmzh616%40psu.edu%7C20dc9f094f2a4a7c1a7a08d8ac58e693%7C7cf48d453ddb4389a9c1c115526eb52e%7C0%7C0%7C637448845118869502%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&amp;sdata=mGneZBhSqIKtg%2F3%2F51%2FR8VG78n6nfVNjrwXLOA%2FAvp8%3D&amp;reserved=0" target="_blank"><span>unusual electromagnetic flashes</span></a><span>,&nbsp;</span><a href="https://nam10.safelinks.protection.outlook.com/?…”
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