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Mostrando 441 - 460 Resultados de 103,170 Para Buscar '"The Hu"', tiempo de consulta: 1.06s Limitar resultados
  1. 441
    “…HuR is a miRNA derepressor protein that can act as miRNA sponge for specific miRNAs to negate their action on target mRNAs. …”
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    MicroRNA exporter HuR clears the internalized pathogens by promoting pro‐inflammatory response in infected macrophages
  2. 442
    “…PBL from healthy human volunteers were administered i.p. into IL-2 receptor γ-chain disrupted SCID mice, and SCID-PBL/hu mice were constructed. These mice can be used to analyze the human immune response in vivo. …”
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    Development of vaccines and passive immunotherapy against SARS corona virus using SCID-PBL/hu mouse models
  3. 443
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    Development of Vaccines and Passive Immunotherapy Against Sars Coronavirus Using Mouse and Scid-PBL/hu Mouse Models
  4. 444
    “…The current study aimed to perform a genome-wide association study (GWAS) to detect significant single-nucleotide polymorphisms (SNPs) that are associated with BW in Hu sheep. The comparison and analysis of the G1 and G2 generations of a nucleus meat Hu sheep breeding herd revealed four SNPs identified by GWAS. …”
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    Genome-Wide Association Study of Body Weights in Hu Sheep and Population Verification of Related Single-Nucleotide Polymorphisms
  5. 445
    “…The RNA-binding protein (RBP) HuD is involved in neuronal differentiation, regeneration, synaptic plasticity and learning and memory. …”
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    HuD Binds to and Regulates Circular RNAs Derived From Neuronal Development- and Synaptic Plasticity-Associated Genes
  6. 446
    “…The goal of this study was to define the functional role of adipocyte-specific expression of the RNA binding protein Human antigen R (HuR). Mice with an adipocyte-specific deletion of HuR (Adipo-HuR(−/-)) were generated by crossing HuR floxed (HuR(fl/fl)) mice with mice expressing adiponectin-driven cre-recombinase (Adipoq-cre). …”
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    HuR expression in adipose tissue mediates energy expenditure and acute thermogenesis independent of UCP1 expression
  7. 447
    “…OBJECTIVE: To investigate the effects of HuR protein on the treatment of chronic lymphocytic leukemia (CLL). …”
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    HuR Affects Proliferation and Apoptosis of Chronic Lymphocytic Leukemia Cells via NF-κB Pathway
  8. 448
    “…BACKGROUND: Human recombinant erythropoietin (rHuEPO) is often used in the treatment of diseases associated with a decreased production of red blood cells (RBC), such as chronic renal failure. rHuEPO is typically administered as an intravenous or subcutaneous (SC) injection every few days. …”
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    Proof-of-concept study on improved efficacy of rHuEPO administered as a long-term infusion in rats
  9. 449
    “…Dendritic arbor morphology influences how neurons receive and integrate extracellular signals. We show that the ELAV/Hu family RNA-binding protein Found in neurons (Fne) is required for space-filling dendrite growth to generate highly branched arbors of Drosophila larval class IV dendritic arborization neurons. …”
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    The ELAV/Hu protein Found in neurons regulates cytoskeletal and ECM adhesion inputs for space-filling dendrite growth
  10. 450
    “…While lipopolysaccharide causes nuclear-cytoplasmic translocation of HuR, it enhances cellular La expression. Remarkably, La and HuR were found to bind cooperatively to the PDCD4 mRNA and mitigate miR-21-mediated translation repression. …”
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    RNA-binding proteins La and HuR cooperatively modulate translation repression of PDCD4 mRNA
  11. 451
    “…An oriental herbal formula, Xiao Chai Hu Tang (XCHT), has been used to treat PU for an extended period in China. …”
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    Xiao Chai Hu Tang for Peptic Ulcers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
  12. 452
    “…Human leukapheresis peripheral blood (LPB)- and cord blood (CB)-derived CD34(＋) cells have a similar capacity to reconstitute myeloid lineage cells in a humanized mice (hu-mice) model. However, potent stem cells, such as CB-CD34(＋) cells, efficiently reconstitute the lymphoid system in vivo compared to LPB-CD34(＋) cells. …”
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    Distinct Repopulation Activity in Hu-Mice between CB- and LPB-CD34(＋) Cells by Enrichment of Transcription Factors
  13. 453
    “…Functionally, Pirh2-mediated degradation of HuR augmented the level of c-Myc expression, whose RNA level is otherwise attenuated by HuR. …”
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    The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase
  14. 454
    “…BACKGROUND AND OBJECTIVE: We aimed to predict the targets and signal pathways of Xiao-Chai-Hu-Tang (XCHT) in the treatment of colorectal cancer (CRC) based on network pharmacology, just as well as to further analyze its anti-CRC material basis and mechanism of action. …”
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    Network pharmacology and molecular docking study on the mechanism of colorectal cancer treatment using Xiao-Chai-Hu-Tang
  15. 455
    “…Zebrafish homozygous for the hu2787 non-sense mutation allele of fmr1 are widely used to model FXS, although FXS-relevant phenotypes seen from morpholino antisense oligonucleotide (morpholino) suppression of fmr1 transcript translation were not observed when hu2787 was first described. …”
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    Zebrafish Chromosome 14 Gene Differential Expression in the fmr1(hu2787) Model of Fragile X Syndrome
  16. 456
    “…Therefore, creating and obtaining new therapeutic skills against HuR protein could prove to be the answer to pancreatic cancer therapy. …”
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    Divulging the Critical Role of HuR in Pancreatic Cancer as a Therapeutic Target and a Means to Overcome Chemoresistance
  17. 457
    “…Hu sheep (Ovis aries) is a rare white sheep breed, with four different types of lambskin patterns that have different values. …”
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    PAPPA2 Promote the Proliferation of Dermal Papilla Cells in Hu Sheep (Ovis aries) by Regulating IGFBP5
  18. 458
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    Nuclear depletion of RNA-binding protein ELAVL3 (HuC) in sporadic and familial amyotrophic lateral sclerosis
  19. 459
    “…Thus, we developed the Engage-HU randomized controlled trial (NCT03442114) as a novel approach to address HU utilization barriers. …”
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    Effects of the COVID-19 Pandemic on Caregivers of Young Children with Sickle Cell Disease Enrolled in the Engage-HU Trial
  20. 460
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    MANIFESTO: a huMAN-centric explaInable approach for FakE news spreaders deTectiOn
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