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941“…Regarding the mechanism, circ‐CCND1 physically bound to human antigen R (HuR) protein to enhance CCND1 mRNA stability; on the other hand, circ‐CCND1 could act as an effective sponge for miR‐646 to alleviate the repression of miR‐646 on CCND1 mRNA. …”
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943por Zhang, Gaixia, Wang, Hui, Jiang, Jiemei, Wang, Qiuling, Li, Baoli, Shi, Linchun, Wei, Jianhe“…Wolff) Shan & Yin Li (Apiaceae), a new substitution for the popular Chinese medicinal material, Bupleuri Radix (Chai hu), is not easily distinguishable via traditional methods. …”
Publicado 2021
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944“…The DRPLM group had increased (p ≤ 0.05) apparent digestibility and had altered ruminal fermentation characteristics. (4) Conclusions: replacement of SBM with DDGS in a diet with adequate metabolizable protein and by-pass amino acids (lysine and methionine) could maintain the growth performance of Hu sheep.…”
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945“…Serology testing detected anti-Hu and anti-SOX-1 antibodies. Despite steroid pulse therapy, various anticonvulsants, continuous intravenous sedation, and a fourth course of chemotherapy without atezolizumab, his condition failed to improve. …”
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946por Jain, Aditi, McCoy, Matthew, Coats, Carolyn, Brown, Samantha Z., Addya, Sankar, Pelz, Carl, Sears, Rosalie C., Yeo, Charles J., Brody, Jonathan R.“…Exogenous overexpression of BARD1 in HuR-deficient cells partially rescued the HRR dysfunction, independent of an HuR pro-oncogenic function. …”
Publicado 2022
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948
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949“…HU protein, a member of the nucleoid-associated group of proteins, is an important transcription factor in bacteria, including in the dangerous human pathogen Francisella tularensis. …”
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950por Kaur, Kawaljit, Sun, Yujie, Kanayama, Keiichi, Morinaga, Kenzo, Hokugo, Akishige, Nishimura, Ichiro, Jewett, Anahid“…RESULTS: Percentages of B cells are much higher in wild-type mice whereas the proportions of immune subsets in humans and reconstituted hu-BLT peripheral-blood are similar. Therefore, hu-BLT mice are preferable model to study human disease, in particular, immune-pathologies induced by ZOL and denosumab. …”
Publicado 2023
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951por Jaacks, Lindsay M., Bliznashka, Lilia, Craig, Peter, Eddleston, Michael, Gathorne-Hardy, Alfred, Kumar, Ranjit, Mohan, Sailesh, Norrie, John, Rajan, Sheril, Roy, Aditi, Yandrapu, Bharath, Srinivasapura Venkateshmurthy, Nikhil, Prabhakaran, Poornima“…The BLOOM study (co-Benefits of Largescale Organic farming On huMan health) aims to determine if a government-implemented agroecology programme reduces pesticide exposure and improves dietary diversity in agricultural households. …”
Publicado 2023
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952por Intelligence and Neuroscience, ComputationalEnlace del recurso
Publicado 2023
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953por Yao, Yuanshan, Chen, Chunji, Wang, Jing, Xuan, Haojie, Chen, Xiuxiu, Li, Zheng, Yang, Fuzhi, Wang, Bin, Lin, Siyun, Li, Saitian, Tang, Dongfang, Gong, Libao, Gao, Wen“…From a mechanistic standpoint, circATP9A can interact with the HuR protein to form an RNA–protein complex, subsequently amplifying the mRNA and protein levels of the target gene NUCKS1. …”
Publicado 2023
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954“…Upregulation of CD23 in huASMC by IL-4 and GM-CSF can contribute to changes in huASMC and may provide an avenue for new therapeutic options in asthma targeting ASMC.…”
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955por Lapenta, Caterina, Santini, Stefano M., Logozzi, Mariantonia, Spada, Massimo, Andreotti, Mauro, Di Pucchio, Tiziana, Parlato, Stefania, Belardelli, Filippo“…In this work, we evaluated the capability of DCs pulsed with aldrithiol-2–inactivated HIV-1 in inducing a protective antiviral human immune response in SCID mice reconstituted with human PBL (hu-PBL-SCID mice). Immunization of hu-PBL-SCID mice with DCs generated after exposure of monocytes to GM-CSF/IFN-α (IFN-DCs) and pulsed with inactivated HIV-1 resulted in a marked induction of human anti–HIV-1 antibodies, which was associated with the detection of anti-HIV neutralizing activity in the serum. …”
Publicado 2003
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956por Ladjemi, Maha Z, Chardes, Thierry, Corgnac, Stephanie, Garambois, Veronique, Morisseau, Sebastien, Robert, Bruno, Bascoul-Mollevi, Caroline, Ait Arsa, Imade, Jacot, William, Pouget, Jean-Pierre, Pelegrin, Andre, Navarro-Teulon, Isabelle“…Similarly, prophylactic vaccination with anti-Id scFv69 fully protects virgin or primiparous FVB-MMTV.f.huHER2(Fo5) females from developing spontaneous mammary tumors. …”
Publicado 2011
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957“…PURPOSE: To explore whether, following direct contact, there is mutual influence between pericytes (PC) and endothelial cells (EC), and to establish whether protein kinase C (PKC) activation, a condition associated with hyperglycemia, can affect, via the mRNA-binding Hu-antigen R (HuR)/ELAV protein, the expression of vascular endothelial growth factor (VEGF). …”
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958por Mulay, Vishwaroop, Wood, Peta, Manetsch, Melanie, Darabi, Masoud, Cairns, Rose, Hoque, Monira, Chan, Karen Cecilia, Reverter, Meritxell, Álvarez-Guaita, Anna, Rye, Kerry-Anne, Rentero, Carles, Heeren, Joerg, Enrich, Carlos, Grewal, Thomas“…We demonstrate that in Chinese Hamster Ovary (CHO) cells and human hepatic HuH7 cells, extracellular signal-regulated kinase 1/2 (Erk1/2) inhibition reduces PPARα-inducible ABCA1 protein levels, while ectopic expression of constitutively active H-Ras, K-Ras and MAPK/Erk kinase 1 (Mek1) increases ABCA1 protein expression, respectively. …”
Publicado 2013
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959por Damjanovic, Daniela, Khera, Amandeep, Afkhami, Sam, Lai, Rocky, Zganiacz, Anna, Jeyanathan, Mangalakumari, Xing, Zhou“…Using a murine model of subcutaneous BCG immunization followed by intranasal AdHu5Ag85A boosting, we investigated the impact of age at BCG immunization on protective efficacy of BCG prime and AdHu5Ag85A boost immunization-mediated protection. …”
Publicado 2015
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960“…We also established 2 different cell lines from spontaneous lung metastases and cell lines from a serial transplantation of tumor tissues in HuHER2 transgenic mice. HuHER2 protein was overexpressed in all of the established cell lines. …”
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