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981por Yoshida, Atsushi, Tanaka, Reiko, Kodama, Akira, Yamamoto, Naoki, Ansari, Aftab A., Tanaka, Yuetsu“…Human CD4(+) T cells were thus recovered from the HIV-DC-immunized hu-PBL-SCID mice and were re-stimulated in vitro by co-culture for 2 days with autologous adherent PBMC as antigen presenting cells, APC previously pulsed with inactivated HIV in IL-2-containing medium to expand HIV-1-reactive CD4(+) T cells. …”
Publicado 2005
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982por Ramgolam, Vinod S., DeGregorio, Scott D., Rao, Gautham K., Collinge, Mark, Subaran, Sharmila S., Markovic-Plese, Silva, Pardi, Ruggero, Bender, Jeffrey R.“…LFA-1 engagement-induced translocation of HuR and stabilization of TNF- α mRNA was lost in Jurkat cells deficient in the Rac guanine nucleotide exchange factor Vav-1 (J.Vav1). …”
Publicado 2010
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983por Hicks, Stuart W., Tarantelli, Chiara, Wilhem, Alan, Gaudio, Eugenio, Li, Min, Arribas, Alberto J., Spriano, Filippo, Bordone, Roberta, Cascione, Luciano, Lai, Katharine C., Qiu, Qifeng, Taborelli, Monica, Rossi, Davide, Stussi, Georg, Zucca, Emanuele, Stathis, Anastasios, Sloss, Callum M., Bertoni, Francesco“…In conclusion, huB4-DGN462 is an attractive candidate for clinical investigation in patients with B-cell malignancies.…”
Publicado 2019
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984por Zhang, Chu-di, Wang, Yi-long, Zhou, Dong-ming, Zhu, Meng-ying, Lv, Yao, Hao, Xiao-qiang, Qu, Chu-fan, Chen, Yi, Gu, Wei-zhong, Wu, Ben-qing, Chen, Pei-chun, Zhao, Zheng-yan“…However, the oncolytic effects and underlying mechanisms of the recombinant Chinese measles virus vaccine strain Hu191 (rMV-Hu191) against human colorectal cancer (CRC) remain elusive. …”
Publicado 2021
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985por Hu, Xuehao, Chen, Yuhang, Gao, Shixin, Min, Rui, Woyessa, Getinet, Bang, Ole, Qu, Hang, Wang, Heng, Caucheteur, ChristopheEnlace del recurso
Publicado 2022
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986por Zhong, Wei-Fang, Tong, Wing-Sum, Zhou, Shan-Shan, Yip, Ka-Man, Li, Song-Lin, Zhao, Zhong-Zhen, Xu, Jun, Chen, Hu-Biao“…Bai-Hu-Tang (BHT), a classic traditional Chinese medicine (TCM) formula used for clearing heat and promoting body fluid, consists of four traditional Chinese medicines, i.e., Gypsum Fibrosum (Shigao), Anemarrhenae Rhizoma (Zhimu), Glycyrrhizae Radix et Rhizoma Praeparata cum Melle (Zhigancao), and nonglutinous rice (Jingmi). …”
Publicado 2017
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987por Guo, Xinying, Zhang, Gaolong, Cai, Weihua, Huang, Fa, Qin, Jingwen, Song, Xingrong“…Furthermore, we found peripheral nerve damage induced Rmst increase could interact with RNA-binding protein HuR to stabilize the Dnmt3a mRNA. CONCLUSION: Our findings reveal a crucial role of Rmst in damaged DRG neurons under NP condition and provide a novel target for drug development against NP.…”
Publicado 2023
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988por Xia, Xiaona, Zhang, Xiaoqian, Cui, Jiufa, Jiang, Qingjun, Guan, Shuai, Liang, Kongming, Wang, Hao, Wang, Chao, Huang, Chencui, Dong, Hao, Han, Kai, Meng, Xiangshui“…RESULTS: The ROC analysis showed that a dHU >2.5 was a critical value to predict the poor outcomes (mRS >3) in sICH. …”
Publicado 2023
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989“…Meanwhile, the expression levels of HuR and IGF2BP1 are also reduced by calycosin. More importantly, calycosin facilitates the downregulation of HuR and IGF2BP1 caused by decreasing lncRNA HOTAIR expression, and the upregulation of HuR and IGF2BP1 caused by overexpression of lncRNA HOTAIR is weakened by calycosin. …”
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990por Izquierdo, José M.“…The repressor activity of hnRNP C1 on Fas exon 6 splicing is mediated by Hu antigen R (HuR). Experiments involving tethering approaches showed that the repressor capacity of hnRNP C1 is associated with an exonic splicing silencer in Fas exon 6. …”
Publicado 2010
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991por Marchesi, Nicoletta, Thongon, Natthakan, Pascale, Alessia, Provenzani, Alessandro, Koskela, Ali, Korhonen, Eveliina, Smedowski, Adrian, Govoni, Stefano, Kauppinen, Anu, Kaarniranta, Kai, Amadio, Marialaura“…Here, we studied the early effects of the proautophagy AICAR + MG132 cotreatment on the HuR-p62 pathway. We treated ARPE-19 cells with Erk1/2, AMPK, p38(MAPK), PKC, and JNK kinase inhibitors in the presence of AICAR + MG132 and evaluated HuR localization/phosphorylation and p62 expression. …”
Publicado 2018
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992por Wu, Tianyi, Wang, Shanhe, Wang, Lihong, Zhang, Weibo, Chen, Weihao, Lv, Xiaoyang, Li, Yue, Hussain, Zahid, Sun, Wei“…CTTN-IT1 is a novel lncRNA that is a competing endogenous RNA (ceRNA) of miR-29a and can promote SMSC proliferation and differentiation by restoring the expression of YAP1 when it is inhibited by miR-29a in Hu sheep. Overall, our findings construct a CTTN-IT1-miR-29a-YAP1 regulatory network that will help contribute new insight into improving the muscle development of Hu sheep.…”
Publicado 2020
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994por Wan, Zhen, Yang, Hua, Chen, Peiyong, Wang, Zhibo, Cai, Yu, Yao, Xiaolei, Wang, Feng, Zhang, Yanli“…This work illustrates that the lncRNA SM2 regulates gonadotropin secretion in the Hu sheep anterior pituitary by targeting the oar-miR-16b/TGF-β/SMAD2 signaling pathway, providing a valuable resource for understanding the molecular mechanisms underlying sheep reproduction.…”
Publicado 2022
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996por Zou, Peng, Povoski, Stephen P, Hall, Nathan C, Carlton, Michelle M, Hinkle, George H, Xu, Ronald X, Mojzisik, Cathy M, Johnson, Morgan A, Knopp, Michael V, Martin, Edward W, Sun, Duxin“…RESULTS: At approximately 1 hour after i.v. injection, (124)I-HuCC49deltaC(H)2 was distributed within the systemic circulation, while at approximately 1 hour after i.p. injection, (124)I-HuCC49deltaC(H)2 was distributed within the peritoneal cavity. …”
Publicado 2010
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997por Martinez-Saez, Nuria, Hochkogler, Christina Maria, Somoza, Veronika, del Castillo, Maria Dolores“…Serotonin and glucagon-like peptide-1 (GLP-1) release by differentiated Caco-2 and HuTu-80 cells, respectively, was stimulated by the CFB (355% at a concentration of 0.5 mg/mL and 278% at a concentration of 0.05 mg/mL) to the same order of magnitude as those of the SCB. …”
Publicado 2017
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998por Nagaoka, Kentaro, Konno, Satoshi, Murase, Kazunori, Kikuchi, Taisei, Morinaga, Yoshitomo, Yanagihara, Katsunori, Nakagawa, IchiroEnlace del recurso
Publicado 2019
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999por Song, Xiaojin, Chen, Bing, Liang, Yiran, Li, Yaming, Zhang, Hanwen, Han, Dianwen, Wang, Yajie, Ye, Fangzhou, Wang, Lijuan, Zhao, Wenjing, Yang, Qifeng“…Further experiments showed that circEIF3H did not function as a microRNA sponge as in the most well-established pathway, but as a scaffold for IGF2BP2 and HuR to regulate the mRNA stability of HSPD1, RBM8A, and G3BP1. …”
Publicado 2022
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1000“…The binding relationships among SNHG3, miR-34b-5p, and HuR were validated, in addition to analyzing the binding between HuR and HOXC6. …”
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