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  1. 1
    por Gigli, Irma, Austen, K. Frank
    Publicado 1969
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    FLUID PHASE DESTRUCTION OF C2(hu) BY C1(hu) : II. UNMASKING BY C4i(hu)OF C1(hu) SPECIFICITY FOR C2(hu)
  2. 2
    “…However, the role of the neural-specific members HuB, HuC, and HuD (ELAVL2–4) in telomerase activity is unknown. …”
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    HuB and HuD repress telomerase activity by dissociating HuR from TERC
  3. 3
    “…The RNA-binding protein, HuR, associates with the HuR mRNA, but the consequences of this interaction are unknown. …”
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    Reduced nuclear export of HuR mRNA by HuR is linked to the loss of HuR in replicative senescence
  4. 4
    “…Here, we review the regulatory role of Hu antigen R (HuR), a ubiquitous member of the ELAV/Hu family of RNA-binding proteins (RBPs), in the pathogenesis, progression, and treatment of HCC and CCA. …”
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    Hu Antigen R (HuR) Protein Structure, Function and Regulation in Hepatobiliary Tumors
  5. 5
    “…Interestingly, we found two HuSWEET genes, HuSWEET12a and HuSWEET13d, that showed strong preferential expressions in fruits and an upward trend during fruit maturation, suggesting they have key roles in sugar accumulation in pitaya. …”
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    Identification of HuSWEET Family in Pitaya (Hylocereus undatus) and Key Roles of HuSWEET12a and HuSWEET13d in Sugar Accumulation
  6. 6
    por Li, Lai-Fu, Zhang, He
    Publicado 2013
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    Professor Da-Yi Hu
  7. 7
    Publicado 2019
    “…First Person is a series of interviews with the first authors of a selection of papers published in Biology Open helping early-career researchers promote themselves alongside their papers. Qingting Hu is first author on ‘Role of ALDH1A1 and HTRA2 expression in CCL2/CCR2-mediated breast cancer cell growth and invasion’, published in BIO. …”
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    First person – Qingting Hu
  8. 8
    por Patel, Prachi
    Publicado 2022
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    A Conversation with Liangbing Hu
  9. 9
    “…Our aim was to investigate the expression of HuR and its targets in a methionine-choline deficient (MCD) model of NAFLD. …”
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    MCD Diet Modulates HuR and Oxidative Stress-Related HuR Targets in Rats
  10. 10
    “…The Hu RNA-binding protein family consists of four members: HuR/A, HuB, HuC and HuD. …”
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    Promotion of exon 6 inclusion in HuD pre-mRNA by Hu protein family members
  11. 11
    “…We also analyzed a hundred of 3D fold comparative models built for HU sequences from all revealed HU clades. It appears that HU fold remains similar in spite of the HU sequence variations. …”
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    Comparison of histone-like HU protein DNA-binding properties and HU/IHF protein sequence alignment
  12. 12
    “…Mechanistically, circ-HuR interacted with CCHC-type zinc finger nucleic acid binding protein (CNBP), and subsequently restrained its binding to HuR promoter, resulting in down-regulation of HuR and repression of tumor progression. …”
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    Circ-HuR suppresses HuR expression and gastric cancer progression by inhibiting CNBP transactivation
  13. 13
    “…Additionally, we could show that miR-194-5p can regulate HuR expression level. HuR knockdown in melanoma cells led to the suppression of proliferation and the induction of cellular senescence. …”
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    HuRdling Senescence: HuR Breaks BRAF-Induced Senescence in Melanocytes and Supports Melanoma Growth
  14. 14
    por Patel, Prachi
    Publicado 2022
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    Correction to “A Conversation with Liangbing Hu”
  15. 15
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    Correction: Circ-HuR suppresses HuR expression and gastric cancer progression by inhibiting CNBP transactivation
  16. 16
    “…AIM: In paraneoplastic neurological syndromes (PNS) associated with small cell lung cancer (SCLC) and Hu antibodies (Hu-PNS), Hu antigens expressed by the tumour hypothetically trigger an immune response that also reacts with Hu antigens in the nervous system, resulting in tumour suppression and neuronal damage. …”
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    No evidence for circulating HuD-specific CD8(+) T cells in patients with paraneoplastic neurological syndromes and Hu antibodies
  17. 17
    “…JAK3 phosphorylated HuR at tyrosine 200, in turn inhibiting HuR localization in SGs, reducing HuR interaction with targets SIRT1 and VHL mRNAs, and accelerating target mRNA decay. …”
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    Tyrosine phosphorylation of HuR by JAK3 triggers dissociation and degradation of HuR target mRNAs
  18. 18
    “…The RNA-binding protein Hu antigen R (HuR) binds to AU-rich elements (ARE) in the 3’-untranslated region (UTR) of target mRNAs. …”
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    The fungal natural product azaphilone-9 binds to HuR and inhibits HuR-RNA interaction in vitro
  19. 19
    “…The goal of our study was to analyze the gene and protein expression of HuB, HuC, and HuD in DRG sensory neurons in diabetes. …”
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    RNA-Binding Proteins HuB, HuC, and HuD are Distinctly Regulated in Dorsal Root Ganglia Neurons from STZ-Sensitive Compared to STZ-Resistant Diabetic Mice
  20. 20
    por Mansfield, Kyle D., Keene, Jack D.
    Publicado 2012
    “…However, the three neuron-specific ELAV/Hu proteins, HuB, HuC and HuD, while binding to the same types of mRNAs, are required instead for neuronal differentiation, and it becomes difficult to reconcile these contrary functions when all four Hu proteins are expressed in the same neuron. …”
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    Neuron-specific ELAV/Hu proteins suppress HuR mRNA during neuronal differentiation by alternative polyadenylation
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