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4381por Xu, Amy Y., Blanco, Marco A., Castellanos, Maria Monica, Meuse, Curtis W., Mattison, Kevin, Karageorgos, Ioannis, Hatch, Harold W., Shen, Vincent K., Curtis, Joseph E.“…The results suggest that solution pH significantly influences mAb flexibility and thus could help mAbs remain physically stable by maximizing local electrostatic repulsions when mAbs become crowded in solution. Under acidic buffer conditions, both Fab and Fc contribute to the repulsive PPI observed among the full mAb at a low ionic strength. …”
Publicado 2023
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4382A Channel Rendezvous Algorithm for Multi-Unmanned Aerial Vehicle Networks Based on Average Consensus“…Realizing the distributed adaptive network construction of multi-UAV networks is an urgent challenge, as they lack a reliable common control channel and can only maintain a limited sensing range in crowded electromagnetic environments. Multi-unmanned aerial vehicle (UAV) networks are gaining popularity in many fields. …”
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4383“…These results suggest that crowding in the NP ligand shell influences the mechanism of diffusion, with lower grafting densities allowing ligand chain relaxations that facilitate movement through the gel. …”
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4384“…We propose that density-dependent inhibition in cultured 3T3 cells is the result both of an increased requirement for the platelet- derived growth factor as the cultures become more crowded and of inactivation of growth factor activity by growing cells.…”
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4385“…It becomes intelligible why a carrier of pathogenic bacteria may reside in a community without producing infection of the susceptibles about him in spite of the fact that they actually acquire the organisms, why crowding results in the spread of infection, and why the introduction of unusually susceptible people into a community where carriers are present leads not only to infection of these susceptibles but to infection of the general population. …”
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4386“…Only when the pneumococci were encapsulated and the leukocytes derived from inflammatory exudates were crowded together, as in vivo, was the depressive action of the glucose clearly demonstrable.…”
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4387“…CONCLUSION: RAD52 itself being a highly aggregated protein perhaps acts as scaffold to bring together RAD51 and DNA molecules into large co-aggregates of RAD52-RAD51-DNA complexes to promote RAD51 mediated DNA unwinding reaction, when appropriate nucleotide cofactors are available, presumably through macromolecular crowding effects. Our work highlights the functional link between aggregation of protein-DNA complexes and DNA unwinding in RAD51 system.…”
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4388por Renčiuk, D., Kejnovská, I., Školáková, P., Bednářová, K., Motlová, J., Vorlíčková, M.“…Both G(3)(TTAG(3))(3) and long telomeric DNA are also able to adopt the (3 + 1) quadruplex structure: Molecular crowding conditions, simulated here by ethanol, induced a slow transition of the K(+)-stabilized quadruplex into the hybrid quadruplex structure and then into a parallel quadruplex arrangement at increased temperatures. …”
Publicado 2009
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4389“…When entire populations of densely crowded asci germinated, ∼10–25% of the resulting colonies were outcrossed. …”
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4390por Bazazi, Sepideh, Ioannou, Christos C., Simpson, Stephen J., Sword, Gregory A., Torney, Colin J., Lorch, Patrick D., Couzin, Iain D.“…This local aggregation appears to be driven by positive feedback whereby the presence of individuals attracts others, which can lead to further crowding. This work improves our understanding of the local social dynamics driving migratory band formation, maintenance and movement at the population level.…”
Publicado 2010
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4391“…In addition, it wraps whole crowns, providing advantages to deal with crowding, spacing, and size of arch. In short, clear aligner could be a useful treatment option for PTM patient, since it provides decreased probing depth, gingival recession, clinical attachment level, mobility and esthetical restoration.…”
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4392“…The grouping processes we have identified might be important in daily life, such as when we attempt to follow a conversation in a crowded room.…”
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4393por del Alamo, Marta, Hogan, Daniel J., Pechmann, Sebastian, Albanese, Veronique, Brown, Patrick O., Frydman, Judith“…Polypeptides exiting the ribosome must fold and assemble in the crowded environment of the cell. Chaperones and other protein homeostasis factors interact with newly translated polypeptides to facilitate their folding and correct localization. …”
Publicado 2011
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4394“…Such an interplay between food and gut microbiota underlines the importance of the microbiological quality of fermented foods, as the crowded environment of the gut is also an ideal site for genetic exchanges among bacteria. …”
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4395por Lundberg, Martin, Eriksson, Anna, Tran, Bonnie, Assarsson, Erika, Fredriksson, Simon“…Furthermore, we have illustrated the use of a macro-molecular crowding matrix in combination with this homogeneous assay to drive target binding for low-affinity antibodies, thereby improving the sensitivity and increasing affinity reagent availability by lowering assay development dependency on high-affinity antibodies. …”
Publicado 2011
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4396por Geller, Frank, Feenstra, Bjarke, Zhang, Hao, Shaffer, John R., Hansen, Thomas, Esserlind, Ann-Louise, Boyd, Heather A., Nohr, Ellen A., Timpson, Nicholas J., Fatemifar, Ghazaleh, Paternoster, Lavinia, Evans, David M., Weyant, Robert J., Levy, Steven M., Lathrop, Mark, Smith, George Davey, Murray, Jeffrey C., Olesen, Jes, Werge, Thomas, Marazita, Mary L., Sørensen, Thorkild I. A., Melbye, Mads“…The sequence and timing of permanent tooth eruption is thought to be highly heritable and can have important implications for the risk of malocclusion, crowding, and periodontal disease. We conducted a genome-wide association study of number of permanent teeth erupted between age 6 and 14 years, analyzed as age-adjusted standard deviation score averaged over multiple time points, based on childhood records for 5,104 women from the Danish National Birth Cohort. …”
Publicado 2011
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4397por Bertin, Aurélie, McMurray, Michael A., Pierson, Jason, Thai, Luong, McDonald, Kent L., Zehr, Elena A., García, Galo, Peters, Peter, Thorner, Jeremy, Nogales, Eva“…A morphological description of these filaments in the crowded space of the cell is challenging, given their small cross section. …”
Publicado 2012
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4398por Tschinkel, Walter R.“…In all three species, nest size increased more slowly than the worker population, so crowding was greater in large colonies than in small, in contrast to the situation in three other ant species for which data were available. …”
Publicado 2011
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4399“…For instance to improve communication, a listener can select an individual “stream,” such as a talker in a crowded room, based on cues such as pitch or location. …”
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4400“…CONCLUSIONS: These findings suggest that children with 22q11.2DS may be particularly susceptible to dynamic crowding of objects with increasing cognitive demands related to monitoring multiple targets reflecting a reduced acuity in spatiotemporal cognitive representation.…”
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