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461“…In spite of incredible advances in modern science, technology and allopathic medicine a large we are unable to provide quality healthcare to all. …”
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462por Gaynes, Robert“…Unprecedented United States/Great Britain cooperation to produce penicillin was incredibly successful by 1943. This success overshadowed efforts to produce penicillin during World War II in Europe, particularly in the Netherlands. …”
Publicado 2017
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463por Reinhardt, Florian, Mathys, Britta, Reinecke, Petra, Neubauer, Hans, Fehm, Tanja, Mohrmann, Svjetlana“…Ductal carcinoma in situ in men is incredibly rare and detection by conventional mammography and ultrasound is often challenging. …”
Publicado 2018
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464por Favero, Gaia, Moretti, Enrico, Bonomini, Francesca, Reiter, Russel J., Rodella, Luigi Fabrizio, Rezzani, Rita“…Melatonin is an endogenous indoleamine with an incredible variety of properties and activities. In recent years, an increasing number of studies have investigated this indoleamine’s interaction with cancerous cells. …”
Publicado 2018
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465“…In the brain, the accurate regulation of these intricate expression programs across different neuronal classes gives rise to an incredible cellular and functional diversity. Newly developed technologies have recently allowed more accurate enhancer mapping and more sophisticated enhancer manipulation, producing rapid progress in our understanding of enhancer biology. …”
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466“…Sofosbuvir, in combination with different partner drugs, has been the molecule that led this incredible change. The last generation of SOF-based regimens, namely Sofosbuvir/Velpatasvir, represents a single tablet, once a day, pangenotypic and pan-fibrotic combination, demonstrated to be safe and effective in almost all type of HCV infected individuals. …”
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467por Kwan, Tristan O. C., Reis, Rosana, Siligardi, Giuliano, Hussain, Rohanah, Cheruvara, Harish, Moraes, Isabel“…However, the study of integral membrane proteins is still incredibly challenging, mostly due to their low expression and instability once extracted from the native biological membrane. …”
Publicado 2019
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468“…Despite the incredible clinical benefits obtained by the use of immune checkpoint blockers (ICBs), resistance is still common for many types of cancer. …”
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469“…The expanding universe of ribosomes not only comprises an incredible richness in ribosomal specialization between species, but also within the same tissues and even cells. …”
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470“…This work reports on the thermal and hydrothermal stability of mechanochemically synthesized ZIF-8 and presents an incredibly simple step to modify the outermost surface of ZIF-8, improving the hydrothermal stability. …”
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471“…This chapter includes diseases of animals in the order Rodentia, in which there are over 2000 species representing 40% of all mammals. This incredibly diverse order includes members inhabiting every continent, either naturally or in human-made environments. …”
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472“…In a few weeks, the global community has witnessed, and for some of us experienced first-hand, the human costs of the COVID-19 pandemic. There is incredible variability in how countries are choosing to thwart the disease’s outbreak, sparking intense discussions around what it means to teach and learn in the era of COVID-19, and more specifically, the role medical students play in the midst of the pandemic. …”
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473“…On the other hand, this country can capitalize on its millennial, incredibly rich story of major achievements in the battle against tuberculosis to develop and implement ad hoc public health programs for the control of the disorder, including targeted and specialized interventions.…”
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474por Kim, Raymond Y, Moroi, Morgan K, Brawley, Amalia, Poley, Marian, King, Tonya S, Olympia, Robert“…The depiction of superheroes and comic book characters in television shows has become incredibly popular. The objective of this study was to determine the positive and negative themes depicted in a select number of superhero-based television shows. …”
Publicado 2020
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475por Alqahtani, Saleh A., Aljumah, Abdulrahman A., Hashim, Almoutaz, Alenazi, Thamer H., AlJawad, Mohammed, Al Hamoudi, Waleed K., Alghamdi, Mohammed Y.“…The high number of severe cases of COVID-19 has placed an unusual burden on health systems, compromising their capacity to provide the regular care that patients with CLD require. Hence, it is incredibly crucial at this juncture to provide a set of interim recommendations on the management of patients with CLD during the current COVID-19 outbreak.…”
Publicado 2020
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476“…Thus, Cancer Systems Immunology holds incredible promise to advance our ability to fight this disease.…”
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477“…Neurons are highly polarised, complex and incredibly energy intensive cells, and their demand for ATP during neuronal transmission is primarily met by oxidative phosphorylation by mitochondria. …”
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478“…Mitochondria entail an incredible dynamism in their morphology, impacting death signaling and selective elimination of the damaged organelles. …”
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479“…Advances in single-cell RNA sequencing over the past decade has shifted the discussion of cell identity toward the transcriptional state of the cell. While the incredible resolution provided by single-cell RNA sequencing has led to great advances in unraveling tissue heterogeneity and inferring cell differentiation dynamics, it raises the question of which sources of variation are important for determining cellular identity. …”
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480“…Diagnosis on the basis of a computerized acoustic examination may play an incredibly important role in early diagnosis and in monitoring and even improving effective pathological speech diagnostics. …”
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