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881“…In contemporary societies’ perception of children, death plays an incredibly insignificant role. This role goes from being ornamental, a weak reminder that our civilisation has overcome the times of children’s high mortality rates, to being some other society’s concern. …”
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882por Habtemariam, Solomon“…The cellular targets that account to the anticancer effect of berberine are incredibly large and range from kinases (protein kinase B (Akt), mitogen activated protein kinases (MAPKs), cell cycle checkpoint kinases, etc.) and transcription factors to genes and protein regulators of cell survival, motility and death. …”
Publicado 2020
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883por Bangi, Erdem“…Rapid development of high throughput genome analysis technologies accompanied by significant reduction in costs has led to the accumulation of an incredible amount of data during the last decade. The emergence of big data has had a particularly significant impact in biomedical research by providing unprecedented, systems-level access to many disease states including cancer, and has created promising opportunities as well as new challenges. …”
Publicado 2020
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884“…The decades of excellent RSV surveillance data that are available from the developed countries of the world are incredibly instructive in advancing public health initiatives in those regions. …”
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885por Chowdhury, Zachariah“…The purpose of bringing forth this present case, an extranodal neoplasm with plasmacytoid morphology at vertebral location in a young adult, is to highlight the diagnostic perils and pitfalls, the clues to unravel the quandaries and thus, the incredible utility of histopathological examination and immunohistochemical analysis in attaining the unerring diagnosis.…”
Publicado 2021
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886“…They have gained significant attention and an incredible interest in the field of nanotechnology and biomedical science, which is merely due to their considerable and exclusive attributes; including their enhanced electron transferability, photobleaching and photo-blinking effects, high photoluminescent quantum yield, fluorescence property, resistance to photo-decomposition, increased electrocatalytic activity, good aqueous solubility, excellent biocompatibility, long-term chemical stability, cost-effectiveness, negligible toxicity, and acquaintance of large effective surface area-to-volume ratio. …”
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887“…However, current research indicates glycan-coated MNPs are an incredibly cost-effective method for rapid food pathogen extraction and concentration.…”
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888por Kim, Bohee, Lingappa, Usha Farey, Magyar, John, Monteverde, Danielle, Valentine, Joan Selverstone, Cho, Jaeheung, Fischer, Woodward“…However, the inherent reactivity and lability of these complexes—the same chemical characteristics that make them uniquely important in biogeochemistry—also make them incredibly difficult to measure. Here we present experimental results demonstrating the limits of common analytical methods used to quantify these complexes. …”
Publicado 2022
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889“…The common risk factor approach (CRFA) for controlling the risk factors associated with NCDs and PD ensures that modifying a few risk factors has an incredible impact on regulating many chronic conditions. …”
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890por Hancox, E., Derry, M. J., Greenall, M. J., Huband, S., Al-Shok, L., Town, J. S., Topham, P. D., Haddleton, D. M.“…This work reveals that these telechelic homopolymers mimic high χ-ultralow N diblock copolymers and enables reproducible targeting of nanomorphologies with incredibly small, tunable domain size.…”
Publicado 2022
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891por Marzocchi, Silvia, Caboni, Maria Fiorenza, Greco Miani, Marcello, Pasini, Federica“…Wheat germ (WG)’s shelf life after the milling process is incredibly short because of the presence of enzymes that aggravate the oxidation process; thus, stabilization is required in order to exploit the nutrients and bioactive compounds within WG. …”
Publicado 2022
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892“…Despite the common occurrence of such injuries, reconstruction can be incredibly challenging and often may focus on a single tissue, which has been damaged to a greater extent, rather than the environment as a whole. …”
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893“…Given the number of enzymes that exist in nature and the incredible potential of directed evolution, the field of synthetic biology contains perhaps all the necessary building blocks to bring about the realization of applied enzymatic retrosynthesis. …”
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894“…Although most of our current understanding comes from studies that relied on information derived from a limited number of pathosystems, newer studies concerning the incredibly diverse interactions between plants and microbes are providing additional insights into other novel mechanisms. …”
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895“…This is further complicated by the incredible clinical and genetic heterogeneity of the disorder that is not captured in most mammalian models. …”
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896“…However, in patients with normal vital signs and an unremarkable physical exam, this diagnosis can be incredibly difficult. As such, the need for a broad differential in the setting of abdominal pain is imperative to avoid missing the diagnosis. …”
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897por Palaniappan, Umamagesh, Kannaiyan, Jaianand, Paulraj, Balaji, Karuppiah, Ponmurugan, Basavarajappa, Santhosh, Syed, Asad, Elgorban, Abdallah M., Zaghloul, Nouf S., Veeramanikandan, Veeramani“…[Image: see text] Therapies based on mesenchymal stem cells have incredible potential for tissue regeneration. Tracking cells and keeping them at the injury site are creating challenges. …”
Publicado 2023
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898“…Online interactions of patients, data on effective treatments, and data collected by wearable devices may represent an incredible source of psychological, sociological, and physiological pain-related information. …”
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899por Ye, Yicheng, Tian, Hao, Jiang, Jiamiao, Huang, Weichang, Zhang, Ruotian, Li, Huaan, Liu, Lu, Gao, Junbin, Tan, Haixin, Liu, Meihuan, Peng, Fei, Tu, Yingfeng“…Such a strategy of dynamic vaccine delivery system enables the active activation of immune system based on the magnetically actuated OCS‐robots, which presents a plausible paradigm for incredibly efficient cancer immunotherapy by designing multifunctional and novel robot platforms in the future.…”
Publicado 2023
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900por Schymanski, Emma L., Zhang, Jian, Thiessen, Paul A., Chirsir, Parviel, Kondic, Todor, Bolton, Evan E.“…These numbers are several orders of magnitude higher than previously established PFAS lists (typically thousands of entries) and pose an incredible challenge to researchers and computational workflows alike. …”
Publicado 2023
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