“…In the current in silico investigation, the guanidine functionality containing drugs and medicinal substances such as metformin, famotidine, neuraminidase inhibitors, antimalarial medications, anticancer drug imatinib, CGP compounds, and human serine protease inhibitor camostat were studied against the above-mentioned therapeutic targets and most of them (especially imatinib) have revealed an incredible spectrum of free docking scores and MD results. …”
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“…Despite exhibiting incredible self-sufficiency, ASFV remains unconditionally dependent on the host translation machinery for its mRNA translation. …”
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“…If the model is further improved, it will be incredibly valuable. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12884-023-05822-z.…”
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“…Through the disruption of fish migration routes, freshwater fish communities have seen an incredible decline. Fishways, which have been constructed to mitigate the problem, have been shown to underperform. …”
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“…Understanding and evaluating the implications of photovoltaic solar panels (PVSPs) deployment on urban settings, as well as the pessimistic effects of densely populated areas on PVSPs efficiency, is becoming incredibly valuable. Thus, the deployment of low-efficiency, low-cost, and widely available PVSPs may diminish total solar reflectance, raising the risks of PVSPs-based urban heating, particularly during the summertime heatwaves. …”
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“…This trial will compare the adapted-NFPP with a generic parenting group-based programme, Incredible Years (IY), which has been recommended for children with preschool-type ADHD symptoms. …”
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“…Results point to an incredibly simple room community where 5–10 taxa, mostly skin-associated, account for over 50% of the amplicon reads. …”
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“…The end goal will be for Qatar to enhance public awareness and engagement and to integrate effectively the incredible advances in research into healthcare systems, for the benefit of all patients. …”
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“…The surgical field has documented disparities for decades and it is incredibly important to continue to challenge our role in patient's access to care, especially during the COVID-19 pandemic.…”
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“…INTERPRETATION: In the face of uncertainty, and an incredibly challenging life-context, informal supporters of domestic abuse survivors demonstrated resilience, creativity, and innovation as they continued to offer support. …”
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“…The task is technically challenging but incredibly useful. With the explosive growth of the digital platform in cyberspace, such as blogs and social networks, individuals and organisations are increasingly utilising public opinion for their decision-making. …”
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“…PURPOSE: Sustainable agri-food production is incredibly important for society. Despite Iran and Malaysia being one of the highest production countries for paddy rice, there is no study on the social life cycle assessment (S-LCA) for rice production for both countries in the literature. …”
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“…OBJECTIVE: Imaging endothelial cell behaviour under physiological conditions, particularly those associated with chronic fibrotic pathologies, is an incredibly challenging endeavour. While short-term assessments (hours) can be achieved with techniques such as intravital microscopy, vascular changes often occur over days and weeks which is unfeasible with current imaging techniques. …”
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“…Both compounds were stabilized in protein–ligand complexes by the π-π stacking, which enabled them to bind to the hMAO-B enzyme's active site incredibly effectively. The hMAO-B was stabilized by B10- and B15-hMAO-B complexes, with binding energies of − 74.57 and − 87.72 kcal/mol, respectively. …”
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“…Additionally, Armillaria is easy to degenerate after multiple generations, and the compatibility between the strains from other areas and G. elata Bl. f. glauca in Changbai Mountain is unstable. Therefore, it is incredibly significant to isolate, identify and screen the symbiotic Armillaria suitable for the growth of G. elata Bl. f. glauca in Changbai Mountain, and to explore the mechanism by which Armillaria improves the production performance of G. elata Bl. f. glauca. …”
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“…The presented comparison between experiment and theory highlight the incredible progress as well as the current limitations in our quest towards a fundamental description of nuclear structure.…”
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“…All types of physical exercise were effective in improving EFs (SMD = 1.15, 95% CI: 0.83 to 1.46), and open-skill activities which require participants to react in a dynamically changing and externally paced environment induced the most incredible benefits for executive functions (SUCRA = 98.0%, SMD = 1.96, and 95% CI: 1.15 to 2.77). …”
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“…Endocrine was consulted and a serum 17-OHP, ACTH and cortisol level was requested. He was an incredibly difficult patient to collect blood work and after multiple attempts only a serum cortisol was collected. …”
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“…Calcium (Ca(2+)) imaging, which has been extensively developed, undoubtedly offers an incredibly good approach, particularly in its versions using genetically encoded calcium indicators. …”
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“…Single-cell expression profiling methods offer an incredibly detailed view of the molecular states of individual cells. …”
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