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  1. 6781
    “…This locus was identified by quantifying the number of rod bipolar cells and Type 2 cone bipolar cells across a panel of recombinant inbred (RI) strains of mice derived from two inbred laboratory strains, C57BL/6J (B6/J) and A/J, and mapping a proportion of that variation in cell number, for each cell type, to this shared locus. …”
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    Xkr8 Modulates Bipolar Cell Number in the Mouse Retina
  2. 6782
    “…A., Lindfors, S., Dumont, V., Van, M., Wang, H., Dash, S. N., Berg, M., Naams, J.-B., Hautala, L. C., Nisen, H., Mirtti, T., Groop, P.…”
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    Metformin increases glucose uptake and acts renoprotectively by reducing SHIP2 activity
  3. 6783
    “…In particular, CBA/CaJ (CBA) mice maintain relatively stable hearing over age while C57BL/6J (B6) mice show a steady decline of hearing, making them a popular model for early onset hearing loss. …”
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    Cellular Differences in the Cochlea of CBA and B6 Mice May Underlie Their Difference in Susceptibility to Hearing Loss
  4. 6784
    “…We initially evaluated induction of HBV-C (K(b)/C93)-specific CD8(+) T cell responses in C57BL/6J (B6) and 1.4HBV-S(mut) transgenic (tg) mice that harbor a replicating HBV genome in hepatocytes by DNA immunization. …”
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    Endogenously Expressed Antigens Bind Mammalian RNA via Cationic Domains that Enhance Priming of Effector CD8 T Cells by DNA Vaccination
  5. 6785
    “…The aim of this study was to test the hypothesis that low CS activity impairs the metabolic health of mice fed a high fat diet (HFD) and promotes palmitate-induced lipotoxicity in muscle cells. C57BL/6J (B6) mice and congenic B6.A-(rs3676616-D10Utsw1)/KjnB6 (B6.A), a strain which carries the A/J allele of CS on the B6 strain background, were fed HFD (45% kcal from fat) for 12 weeks. …”
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    Low Citrate Synthase Activity Is Associated with Glucose Intolerance and Lipotoxicity
  6. 6786
    “…To identify these differences we measured the biometric, neuroendocrine, and transcriptional response to stress among inbred mouse strains with varying degrees of genetic similarity, C57BL/6J (B), C57BL/6NJ (N), and DBA/2J (D). The B and D strains are highly genetically diverse whereas the B and N substrains are highly similar. …”
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    Genetic Factors Mediate the Impact of Chronic Stress and Subsequent Response to Novel Acute Stress
  7. 6787
    “…Cells were transplanted into C57BL/6J (B6, allogeneic), Balb (syngeneic), and FVB/NJ (third-party) mice. …”
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    Potential of Membranes Surrounding the Fetus as Immunoprotective Cell-Carriers for Allogeneic Transplantations
  8. 6788
    “…The rat pancreatic AR42J-B13 (B-13) cell line differentiates into non-replicative hepatocyte-like (B-13/H) cells in response to glucocorticoid. …”
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    Expression of serine/threonine protein kinase SGK1F promotes an hepatoblast state in stem cells directed to differentiate into hepatocytes
  9. 6789
    “…Exercise phenotypes were measured in chromosome substitution strain mice carrying Chromosome 14 from the PWD/PhJ donor strain on the genetic background of a host C57BL/6J (B6) strain (B6.PWD14). Eight week old female and male mice from both strains completed a graded exercise test to exhaustion to assess intrinsic or baseline exercise capacity. …”
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    Contribution of Chromosome 14 to Exercise Capacity and Training Responses in Mice
  10. 6790
    “…Thus, through a paradigm that promoted binge-like food intake through intermittent access to high calorie diet (HCD), we quantified food-intake in four inbred mouse strains: C57Bl/6J (B6), NOD/LtJ (NOD), 129S1/SvlmJ (S1), and A/J (AJ). …”
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    Genetic variation affects binge feeding behavior in female inbred mouse strains
  11. 6791
    “…Interestingly, the severity of the microcephaly in Ttc21b(aln/aln) homozygous null mutants is considerably affected by the genetic background and mutants on an FVB/NJ (FVB) background develop a forebrain significantly smaller than mutants on a C57BL/6J (B6) background. We performed a Quantitative Trait Locus (QTL) analysis to identify potential genetic modifiers and identified two regions linked to differential forebrain size: modifier of alien QTL1 (Moaq1) on chromosome 4 at 27.8 Mb and Moaq2 on chromosome 6 at 93.6 Mb. …”
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    Gpr63 is a modifier of microcephaly in Ttc21b mouse mutants
  12. 6792
    “…METHODS: Intraperitoneal injections of either the mitochondrial uncoupler 2,4 dinitrophenol (DNP) or saline were given to mice with either higher [129S6/eVTac (S6)] or lower [C57BL/6J (B6)] mitochondrial reserve capacities and were studied in dark or light. …”
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    Novel imaging biomarkers for mapping the impact of mild mitochondrial uncoupling in the outer retina in vivo
  13. 6793
    “…Unlike outbred Institute of Cancer Research (ICR) and hybrid mouse strains, genome editing of the most widely used C57BL/6J (B6) strain with i-GONAD has been considered difficult but, recently, setting a constant current of 100 mA upon EP enabled successful i-GONAD in this strain. …”
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    Modification of i-GONAD Suitable for Production of Genome-Edited C57BL/6 Inbred Mouse Strain
  14. 6794
    “…To assess the influence of Tas1r3 polymorphisms on feeding behavior and metabolism, we examined the phenotype of F(1) male hybrids obtained from crosses between the following inbred mouse strains: females from 129SvPasCrl (129S2) bearing the recessive Tas1r3 allele and males from either C57BL/6J (B6), carrying the dominant allele, or the Tas1r3-gene knockout strain C57BL/6J-Tas1r3(tm1Rfm) (B6-Tas1r3-/-). …”
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    Allelic variation of the Tas1r3 taste receptor gene affects sweet taste responsiveness and metabolism of glucose in F(1) mouse hybrids
  15. 6795
    “…We have previously shown that C57BL/6J (B6) mice lose their natural resistance to footpad infection with ectromelia virus (ECTV) due to impaired maturation and recruitment of natural killer (NK) cells to the draining popliteal lymph node (dLN). …”
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    Defective early innate immune response to ectromelia virus in the draining lymph nodes of aged mice due to impaired dendritic cell accumulation
  16. 6796
    “…PURPOSE: To investigate the molecular and cellular mechanisms of cataract induced by cold temperatures in young lenses of wild-type C57BL/6J (B6), wild-type 129SvJae (129), and filensin knockout (KO) mice. …”
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    CP49 and filensin intermediate filaments are essential for formation of cold cataract
  17. 6797
    “…METHODS: We combined C. difficile infection in DBA/1J × B10.Q F1 mice with collagen induced arthritis (CIA). …”
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    Infection With Clostridioides difficile Attenuated Collagen-Induced Arthritis in Mice and Involved Mesenteric T(reg) and T(h2) Polarization
  18. 6798
    “…To study the relationship between APOE4 and age-related cerebrovascular decline, male and female C57BL/6J (B6) mice carrying combinations of APOE alleles including APOE4 (risk) and APOE3 (neutral), as well as B6 controls were assessed at a variety of ages from 4 to 24 mos for cognitive ability, biometrics and cerebrovascular health including i) PET/MRI using 64Cu-PTSM (perfusion) and 18F-FDG (metabolism), ii) transcriptional profiling and iii) immunofluorescence. …”
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    Determining the Role of ApoE4 in Age-Related Cerebrovascular Decline
  19. 6799
    “…In this study, we investigate the consequences of noise exposure in the two commonly used animal models in hearing research, CBA/CaJ (CBA) and C57BL/6J (B6) mice, focusing on the functional changes of cochlear IHCs. …”
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    Differences in Calcium Clearance at Inner Hair Cell Active Zones May Underlie the Difference in Susceptibility to Noise-Induced Cochlea Synaptopathy of C57BL/6J and CBA/CaJ Mice
  20. 6800
    “…V.N. chart review, and literature review were performed by Drs. W.M. and J.B. Outcome measures  Outcome was assessed with the extent of resection and postoperative neurological function. …”
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    Resection of a Recurrent Cervicomedullary Junction Fibromyxoid Sarcoma through a Far Lateral Approach
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