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324“…Bcl-2-related ovarian killer, Bok, was first labeled “pro-apoptotic” due to its ability to cause cell death when over-expressed. …”
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325por Yang, Ming, Vanderwert, Ethan, Kimchi, Eric T., Staveley-O’Carroll, Kevin F., Li, Guangfu“…If liver fibrosis is uncontrolled, it may lead to cirrhosis and even liver cancer, primarily hepatocellular carcinoma (HCC). Natural killer (NK) cells are a key component of innate immunity and have miscellaneous roles in liver health and disease. …”
Publicado 2023
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326por Choi, Haeyoun, Baek, In-Cheol, Park, Soon A, Park, Jae-Sung, Jeun, Sin-Soo, Kim, Tai-Gyu, Ahn, Stephen“…Purpose: The immune responses of natural killer (NK) cells against cancer cells vary by patient. …”
Publicado 2023
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329por Hornett, Emily A, Charlat, Sylvain, Duplouy, Anne M. R, Davies, Neil, Roderick, George K, Wedell, Nina, Hurst, Gregory D. D“…Thus, male killer/host interactions are much more dynamic than previously recognised, with rapid and dramatic loss of the phenotype. …”
Publicado 2006
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331“…Spleen cells from normal nude mice were found to be induced to produce interferon and to exert natural killer (NK) activity on virus persistently infected (PI) tumor cells, and not on uninfected parental cells in vitro. …”
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333Publicado 1986“…IL-2 has been examined for its ability to regulate lymphokine-activated killer (LAK) activity. IL-2 is a potent activator of cytolytic activity against a wide array of tumor cells, including those from fresh autologous and allogeneic tumors. …”
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334“…While the specificity and development of natural killer (NK) cells have been intensely studied, little is known about homeostasis of the mature NK population. …”
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335“…Natural killer cells gauge the absence of self class I MHC on susceptible target cells by means of inhibitory receptors such as members of the Ly49 family. …”
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337por Fox, Lisa M., Cox, Daryl G., Lockridge, Jennifer L., Wang, Xiaohua, Chen, Xiuxu, Scharf, Louise, Trott, David L., Ndonye, Rachel M., Veerapen, Natacha, Besra, Gurdyal S., Howell, Amy R., Cook, Mark E., Adams, Erin J., Hildebrand, William H., Gumperz, Jenny E.“…Natural killer T (NKT) cells are a subset of T lymphocytes with potent immunoregulatory properties. …”
Publicado 2009
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338“…Natural killer cells have been demonstrated to play a major role in mediating an anti-leukemia effect in patients given a T-cell depleted allogeneic hematopoietic stem cell transplantation from an HLA-haploidentical family donor. …”
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339por Higuchi, Darryl A., Cahan, Patrick, Gao, Jian, Ferris, Stephen T., Poursine-Laurent, Jennifer, Graubert, Timothy A., Yokoyama, Wayne M.“…The natural killer gene complex (NKC) on chromosome 6 contains clusters of genes that encode both activation and inhibitory receptors expressed on mouse natural killer (NK) cells. …”
Publicado 2010
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340“…The World Health Organization (WHO) classification recognizes 2 main categories of natural killer (NK) cell-derived neoplasms, namely, extranodal NK/T-cell lymphoma, nasal type, and aggressive NK-cell leukaemia. …”
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