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  1. 21161
    “…Multivariate logistic regression analysis of PrEP use in high-risk MSM showed that more PrEP was used by those who were 26 years or older (OR = 1.86, 95%CI 1.17 ~ 2.99), had master degree or above (OR = 2.37, 95% CI 1.21 ~ 4.72), had unstable work (OR = 1.86, 95% CI 1.16 ~ 2.96), had tested five or more HIV times in the past year (OR = 3.09, 95% CI 1.65 ~ 6.04), had consulted PrEP (OR = 22.05, 95% CI 14.87 ~ 33.91) and had PrEP knowledge awareness (OR = 1.90, 95% CI 1.41 ~ 2.55) (P < 0.05). …”
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    Pre-exposure prophylaxis uptake for high-risk men who have sex with men in China: a multi-city cross-sectional survey
  2. 21162
    “…Primary outcomes were Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) subscales of pain and physical limitation and secondary outcomes were Pain Catastrophizing Scale, Tampa Scale for Kinesiophobia, Pain Self-Efficacy Questionnaire, and Timed "Up & Go" test covering function. …”
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    Examining the influence of pain neuroscience education followed by a Pilates exercises program in individuals with knee osteoarthritis: a pilot randomized controlled trial
  3. 21163
    “…Using an unbiased systems biology approach, we identified a reliance of H3K27M but not isogenic controls to the amino acid methionine, and the enzymes methionine adenosyltransferase 2A (MAT2A), and adenosylmethionine decarboxylase 1 (AMD1). MAT2A is a master regulator of methionine metabolism that converts methionine into the universal methyl donor S-adenosylmethionine (SAM) which is later converted into decarboxylated SAM (dcSAM) by AMD1 for polyamine metabolism. …”
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    DIPG-36. H3K27M HISTONE MUTANT GLIOMAS ARE SENSITIVE TO METHIONINE LOSS AND MAT2A INHIBITION THROUGH A NOVEL FEEDBACK MECHANISM BETWEEN AMD1 AND METTL16
  4. 21164
    “…Compared with PBS treatment, MIC-1 treatment decreased hepatic cholesterol and bile acid levels and reduced expression of HMG-CoA reductase (HMGCR), the master cholesterol metabolism regulator sterol regulatory element-binding protein 2, cholesterol 7α-hydroxylase (CYP7A1), mitochondrial sterol 27-hydroxylase, and oxysterol 7α-hydroxylase. …”
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    Macrophage inhibitory cytokine-1 aggravates diet-induced gallstone formation via increased ABCG5/ABCG8 expression
  5. 21165
    “…This warrants further investigation into this rarer immunophenotype and its clinical significance. BCL6, which is a master transcription factor for the regulation of cell proliferation and key oncogene in B cell lymphomagenesis, has been reported to have co-expression with CD10 in MCL. …”
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    Unveiling the Prognostic Significance of BCL6+/CD10+ Mantle Cell Lymphoma: Meta-Analysis of Individual Patients and Systematic Review
  6. 21166
    “…The International Knee Documentation Committee (IKDC) Score, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Lysholm score, Tegner Activity Scale, and visual analogue scale (VAS) for pain were collected preoperatively and at a minimum of 24 months postoperatively. …”
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    Favorable rates of return to activity and work following lateral closing wedge distal femoral osteotomy for femoral-based symptomatic varus malalignment: an analysis at a mean 6-year follow-up
  7. 21167
    “…We present a detailed 3D reconstruction of the P. cordatum nucleus together with comprehensive proteogenomic insights into the protein equipment mastering the broad spectrum of nuclear processes. …”
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    The enigmatic nucleus of the marine dinoflagellate Prorocentrum cordatum
  8. 21168
    “…A convenience sample of 90 Master of Science in nursing and midwifery students, participated in the study. …”
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    Mental health status and stressful life events among postgraduate nursing students in Cyprus: a cross-sectional descriptive correlational study
  9. 21169
    “…Physical examinations are an important method for women to master their own health status and detect potential health problems, and in recent years, an increasing number of women have actively participated in physical examinations. …”
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    Prevalence of menopausal symptoms and attitudes towards menopausal hormone therapy in women aged 40–60 years: a cross-sectional study
  10. 21170
    “…The primary outcome indicator was the total Western Ontario and McMaster Universities Arthritis Index (WOMAC) score after 6 weeks of treatment. …”
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    Efficacy and safety of combined Chinese and Western medicine in the treatment of knee osteoarthritis: a prospective, multicenter cohort study
  11. 21171
    “…We further analyzed the improvement of improvement of the Visual Analog Scale (VAS) and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) scores and the incidence of adverse events (AEs) after varied dosage injection. …”
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    What is the optimal dose of adipose-derived mesenchymal stem cells treatment for knee osteoarthritis? A conventional and network meta-analysis of randomized controlled trials
  12. 21172
    por Sauve, Florent, Nampoothiri, Sreekala, Clarke, Sophie A., Fernandois, Daniela, Ferreira Coêlho, Caio Fernando, Dewisme, Julie, Mills, Edouard G., Ternier, Gaetan, Cotellessa, Ludovica, Iglesias-Garcia, Cristina, Mueller-Fielitz, Helge, Lebouvier, Thibaud, Perbet, Romain, Florent, Vincent, Baroncini, Marc, Sharif, Ariane, Ereño-Orbea, June, Mercado-Gómez, Maria, Palazon, Asis, Mattot, Virginie, Pasquier, Florence, Catteau-Jonard, Sophie, Martinez-Chantar, Maria, Hrabovszky, Erik, Jourdain, Mercé, Deplanque, Dominique, Morelli, Annamaria, Guarnieri, Giulia, Storme, Laurent, Robil, Cyril, Trottein, François, Nogueiras, Ruben, Schwaninger, Markus, Pigny, Pascal, Poissy, Julien, Chachlaki, Konstantina, Maurage, Claude-Alain, Giacobini, Paolo, Dhillo, Waljit, Rasika, S., Prevot, Vincent
    Publicado 2023
    “…BACKGROUND: We have recently demonstrated a causal link between loss of gonadotropin-releasing hormone (GnRH), the master molecule regulating reproduction, and cognitive deficits during pathological aging, including Down syndrome and Alzheimer's disease. …”
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    Long-COVID cognitive impairments and reproductive hormone deficits in men may stem from GnRH neuronal death
  13. 21173
    “…There were four secondary outcomes, including the extent of pain relief, the change trends of VAS scores, joint function scores measured by the Western Ontario and McMaster University Osteoarthritis Index (WOMAC), and adverse events. …”
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    Efficacy and safety of flurbiprofen cataplasms versus loxoprofen sodium cataplasms in knee osteoarthritis: a randomized controlled trial
  14. 21174
    “…BACKGROUND: Symptom perception is an important process of heart failure (HF) self-care that persons with HF need in order to master self-care management. It also leads to better patient outcomes. …”
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    Feasibility, acceptability, and outcome responsiveness of the SYMPERHEART intervention to support symptom perception in persons with heart failure and their informal caregivers: a feasibility quasi-experimental study
  15. 21175
    “…Virtual reality simulation can provide a safe and controlled environment for students to practice and master skills that are transferable to real-world situations without putting patients, clients, or themselves at risk of any harm. …”
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    Health Care and Social Work Students’ Experiences With a Virtual Reality Simulation Learning Activity: Qualitative Study
  16. 21176
    “…After 2-stage TKA, the mean knee ROM was 119.4° (range, 80°–140°) and the mean Knee Society (KS) knee score was 90.4, the average KS function score was 84.7, the average Hospital for Special Surgery (HSS) score was 87.2, and the average Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score was 16.7. …”
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    SG-APSIC1088: Two-stage primary total knee arthroplasty for evolutive infected arthritis with coexistent joint destruction
  17. 21177
    “…This resulted in high heterogeneity between studies, with the master mix origin and guanidine addition representing significant sources. …”
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    Molecular diagnosis of Chagas disease: a systematic review and meta-analysis
  18. 21178
    “…The Western Ontario and McMaster University (WOMAC) and visual analog scale (VAS) scores were used to assess pain and functional status of the knee joints in both groups before the intervention, immediately post-intervention, and 1, 3, 6, and 12 months after the intervention. …”
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    Impact of autologous platelet-rich plasma therapy vs. hyaluronic acid on synovial fluid biomarkers in knee osteoarthritis: a randomized controlled clinical trial
  19. 21179
    “…Propensity score matching was used for between-groups (I and II, A and B) covariates matching, including age, gender, preoperative lower limb alignment, preoperative medial joint space width (mJSW), preoperative Western Ontario and McMaster Universities osteoarthritis Index (WOMAC) score, wedge size, and postoperative follow-up time. …”
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    Joint line obliquity after lateral closing-wedge high tibial osteotomy does not adversely affect clinical and radiological outcome: a 5-year follow-up study
  20. 21180
    “…We demonstrated that loss of miR-182 leads to an increase in the foregut master marker SOX2. We also used single-cell analyses in murine adult intestinal crypts to support a life-long role for miR-375 in the regulation of Zfp36l2. …”
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    Integrative genome-scale analyses reveal post-transcriptional signatures of early human small intestinal development in a directed differentiation organoid model
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