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241por Mantovani, Oliver, Haffner, Michael, Selim, Khaled A, Hagemann, Martin, Forchhammer, Karl“…Second messengers are a fundamental category of small molecules and ions that are involved in the regulation of many processes in all domains of life. …”
Publicado 2023
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242“…Finally, we highlight the current view on the role of the second messenger c-di-AMP in cell differentiation and the osmotic stress responses with specific emphasis on the two models, S. coelicolor and S. venezuelae.…”
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244por Chalasani, Naga, Vuppalanchi, Raj, Lammert, Craig, Gawrieh, Samer, Braun, Jerome V., Zhuang, Jiali, Ibarra, Arkaitz, Ross, David A., Nerenberg, Michael, Quake, Stephen R., Sninsky, John J., Toden, Shusuke“…METHODS: We performed cell-free messenger RNA (cf-mRNA) sequencing to characterize the circulating transcriptome of PSC and noninvasively investigate potentially bioactive signals that are associated with PSC. …”
Publicado 2023
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245por Zhang, Maorui, Fukushima, Yuta, Nozaki, Kosuke, Nakanishi, Hideyuki, Deng, Jia, Wakabayashi, Noriyuki, Itaka, Keiji“…In this study, to produce additive angiogenic-osteogenic effects in the process of bone regeneration, VEGF and Runt-related transcription factor 2 (Runx2), an essential transcription factor for osteogenic differentiation, were coadministered with messenger RNAs (mRNAs) to bone defects in the rat mandible. …”
Publicado 2023
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247por Baudet, Sarah, Zagar, Yvrick, Roche, Fiona, Gomez-Bravo, Claudia, Couvet, Sandrine, Bécret, Johann, Belle, Morgane, Vougny, Juliette, Uthayasuthan, Sinthuya, Ros, Oriol, Nicol, Xavier“…Second messengers, including cAMP, cGMP and Ca(2+) are often placed in an integrating position to combine the extracellular cues that orient growing axons in the developing brain. …”
Publicado 2023
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251Publicado 1980“…Ovomucoid messenger RNA (mRNAom) comprises approximately 8% of the total mRNA in the estrogen-stimulated oviduct. …”
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253Publicado 1988“…The stored mRNA is stabilized and may be prevented from being translated in oocytes by the binding of a defined set of oocyte-specific proteins to form messenger RNP (mRNP) particles. A key event in the interaction of protein with mRNA is the phosphorylation of those few polypeptides that bind directly to all classes of polyadenylated mRNA. …”
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254Publicado 1995“…Actin modulating proteins that bind polyphosphoinositides, such as phosphatidylinositol 4, 5-bisphosphate (PIP2), can potentially participate in receptor signaling by restructuring the membrane cytoskeleton and modulating second messenger generation through the phosphoinositide cycle. …”
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256por Caroppo, Rosa, Gerbino, Andrea, Fistetto, Gregorio, Colella, Matilde, Debellis, Lucantonio, Hofer, Aldebaran M., Curci, Silvana“…It is generally assumed that the functional consequences of stimulation with Ca(2+)-mobilizing agonists are derived exclusively from the second messenger action of intracellular Ca(2+), acting on targets inside the cells. …”
Publicado 2004
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257por Calapez, Alexandre, Pereira, Henrique M., Calado, Angelo, Braga, José, Rino, José, Carvalho, Célia, Tavanez, João Paulo, Wahle, Elmar, Rosa, Agostinho C., Carmo-Fonseca, Maria“…fAter being released from transcription sites, messenger ribonucleoprotein particles (mRNPs) must reach the nuclear pore complexes in order to be translocated to the cytoplasm. …”
Publicado 2002
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258“…To investigate how spindle-localized RNAs might influence mitosis, we comprehensively surveyed all messenger RNAs (mRNAs) that bound to microtubules during metaphase in both Xenopus laevis egg extracts and mitotic human cell extracts. …”
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260“…The localization of messenger RNAs (mRNAs) on the surface of mitochondria was recently shown to involve specific classes of protein and could be an important regulatory step. …”
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