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  1. 10101
    por Lin, Xiaoming, Chen, Yuhan
    Publicado 2018
    “…Some circRNAs may act as a microRNA (miRNA) sponge to affect miRNA activities in the regulation of messenger RNA (mRNA) expression. However, the circRNA-miRNA-mRNA network in HCC remains largely unknown. …”
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    Identification of Potentially Functional CircRNA-miRNA-mRNA Regulatory Network in Hepatocellular Carcinoma by Integrated Microarray Analysis
  2. 10102
    “…Since the 3′ untranslated regions (3′UTRs) of messenger RNAs (mRNAs) have important roles in translation, localization, and stability of mRNAs through RNA binding proteins (RBPs) and microRNAs (miRNAs), it is important to identify the exact length of 3′UTRs of transcripts in order to understand the precise regulation of gene expression. …”
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    A novel extended form of alpha-synuclein 3′UTR in the human brain
  3. 10103
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    Dissecting the phyloepidemiology of Trypanosoma cruzi I (TcI) in Brazil by the use of high resolution genetic markers
  4. 10104
    “…Although Alpha-fetoprotein (AFP) in blood is widely used in HCC screening and diagnosis, the false-negative rate as high as 30% and 40% is found in advanced HCC and early stage HCC respectively. We detected AFP messenger RNA (mRNA) in extracellular vesicles (EVs) in patient plasma using designed molecular beacons and a novel tethered lipoplex nanoparticle (TLN) biochip. …”
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    Extracellular mRNA detected by molecular beacons in tethered lipoplex nanoparticles for diagnosis of human hepatocellular carcinoma
  5. 10105
    por Wu, Yue, Wu, Ping, Wang, Bin, Shao, Zhu-Qing
    Publicado 2018
    “…Transfer RNA (tRNA) is a category of RNAs that specifically decode messenger RNAs (mRNAs) into proteins by recognizing a set of 61 codons commonly adopted by different life domains. …”
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    Genome-Wide Analysis Reveals Ancestral Lack of Seventeen Different tRNAs and Clade-Specific Loss of tRNA-CNNs in Archaea
  6. 10106
    por Lv, Yuetao, Song, Ge, Li, Peng
    Publicado 2018
    “…Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) was used to detect the expression levels of SOCS-1 messenger RNA (mRNA) in the patients' tumor tissues and adjacent normal tissues. …”
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    Correlation of SOCS-1 gene with onset and prognosis of breast cancer
  7. 10107
    “…METHODS: Quantitative real-time polymerase chain reaction, immunohistochemistry, and western blot analysis were used to examine messenger RNA and protein expression levels. The relationships between HDAC3 expression and clinicopathological variables were analyzed. …”
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    Histone Deacetylase-3 Modification of MicroRNA-31 Promotes Cell Proliferation and Aerobic Glycolysis in Breast Cancer and Is Predictive of Poor Prognosis
  8. 10108
    “…CONCLUSION AND IMPLICATIONS: We hypothesize that PDE1 inhibition improves working memory performance by increasing prefrontal synaptic transmission and/or postsynaptic D(1) receptor signalling, by modulating prefrontal downstream second messenger levels. These data, therefore, support the use of PDE1 inhibitors as a potential approach for the treatment of cognitive dysfunction.…”
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    Targeting the dopamine D(1) receptor or its downstream signalling by inhibiting phosphodiesterase‐1 improves cognitive performance
  9. 10109
    “…Phosphatidylinositol phospholipase Cγ (PLCγ) is an intracellular membrane-associated second-messenger signaling protein activated by tyrosine kinases such as fibroblast growth factor receptor 1. …”
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    Dynamic Allostery in PLCγ1 and Its Modulation by a Cancer Mutation Revealed by MD Simulation and NMR
  10. 10110
    “…The bacterial intracellular second messenger, cyclic dimeric GMP (c-di-GMP), regulates biofilm formation for many bacteria. …”
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    Ligand-Mediated Biofilm Formation via Enhanced Physical Interaction between a Diguanylate Cyclase and Its Receptor
  11. 10111
    “…Evidences support the role of nitric oxide (•NO) as a key messenger both in neurovascular coupling, by signaling from neurons to blood vessels, and in neurometabolic coupling, by modulating O(2) utilization by mitochondria. …”
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    Age-Dependent Impairment of Neurovascular and Neurometabolic Coupling in the Hippocampus
  12. 10112
    “…We built a network of hsa_circ_0000792‐targeted miRNA gene interactions, including miR‐375 and the corresponding messenger RNAs. Gene Ontology analysis revealed that hsa_circ_0000792 could participate in signal transduction and cell communication during LUAD development. …”
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    hsa_circ_0000729, a potential prognostic biomarker in lung adenocarcinoma
  13. 10113
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    Severity of Chagasic Cardiomyopathy Is Associated With Response to a Novel Rapid Diagnostic Test for Trypanosoma cruzi TcII/V/VI
  14. 10114
    “…The aim of the study was to quantitate EZH2 messenger ribonucleic acid (mRNA) expression, evaluate its relation to conditions of prostatitis associated with benign prostatic hyperplasia (BPH), and correlate it with the levels of the inflammatory marker interlukin 6 (IL-6). …”
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    The effect of prostate tissue inflammation in benign prostatic hyperplasia on enhancer of zeste homolog 2 ribonucleic acid expression
  15. 10115
    “…They are able to regulate gene expression by either triggering target messenger RNA degradation or by inhibiting mRNA translation. …”
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    miR-92b promotes autophagy and suppresses viability and invasion in breast cancer by targeting EZH2
  16. 10116
    por Zhao, Xiaoyan, Li, Yuan, Wu, Haibing
    Publicado 2018
    “…In the present study, two messenger ribonucleic acid sequencing datasets of patients with AML were downloaded from the Cancer Genome Atlas and Gene Expression Omnibus databases. …”
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    A novel scoring system for acute myeloid leukemia risk assessment based on the expression levels of six genes
  17. 10117
    “…The markers were divided in broadly four groups: nucleic acids (RNA/DNA/messenger RNA/microRNAs), cytokines, antibodies, and proteins. …”
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    Systematic review of blood diagnostic markers in colorectal cancer
  18. 10118
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    Whole Genome Sequencing in an Acrodermatitis Enteropathica Family from the Middle East
  19. 10119
    “…C3 DNA methylation was measured for 7 CpGs by pyrosequencition using the Pyromark technology (Qiagen, Madrid Spain). C3 messenger RNA (mRNA) levels were analyzed by pre-designed Taqman assays (Applied biosystems, Foster City, CA, USA) and ASP/C3a was measured using a ELISA kit. …”
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    Complement Factor C3 Methylation and mRNA Expression Is Associated to BMI and Insulin Resistance in Obesity
  20. 10120
    “…Prognostic significance was assessed by univariate and multivariate analyses. RESULTS: S100A13 messenger RNA was overexpressed in NSCLC, especially in advanced stage. …”
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    Overexpression of S100A13 protein is associated with tumor angiogenesis and poor survival in patients with early‐stage non‐small cell lung cancer
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