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10241por Zhang, Qian, Cai, Yuping, Kurbatov, Vadim, Khan, Sajid A., Lu, Lingeng, Zhang, Yawei, Johnson, Caroline H.“…The relationship between the messenger RNA (mRNA) expression, copy number variation (CNVs), and mutations of m6A “Writers,” “Readers,” and “Erasers,” prognosis, immune cell infiltration, and genetic mutations in CRC cases were analyzed. …”
Publicado 2020
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10242por Alhubail, Asma, Sewify, May, Messenger, Grace, Masoetsa, Richard, Hussain, Imtiaz, Nair, Shinu, Tiss, AliEnlace del recurso
Publicado 2020
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10243“…Tastant binding to the receptor activates downstream secondary messenger pathways leading to depolarization and increased intracellular calcium in TRCs, that in turn innervate the gustatory cortex in the brain. …”
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10244por Filice, Federica, Janickova, Lucia, Henzi, Thomas, Bilella, Alessandro, Schwaller, Beat“…PV expression is often reduced at both messenger RNA (mRNA) and protein levels in human ASD brain samples and mouse ASD (and schizophrenia) models. …”
Publicado 2020
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10245por Deng, Yu, Xu, Yangbin, Xu, Shuqia, Zhang, Yujing, Han, Bing, Liu, Zheng, Liu, Xiangxia, Zhu, Zhaowei“…This study aimed to identify long non-coding RNAs (lncRNAs), microRNAs (miRNAs), and messenger RNAs (mRNAs) differentially expressed (DE) during keloid formation, predict DElncRNA-DEmiRNA-DEmRNA interactions, and construct a competing endogenous RNA (ceRNA) network through secondary data mining of keloid-related sequencing and microarray data in the open-source Gene Expression Omnibus (GEO) database. …”
Publicado 2020
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10246por Takahashi, Hajime, Nakagawa, Kazuki, Yamada, Haruhiko, Mori, Hidetsugu, Oba, Shimpei, Toyama, Keiko, Takahashi, Kanji“…Based on quantitative reverse transcription polymerase chain reaction (qRT-PCR), S1PR1 messenger ribonucleic acid (mRNA) levels in the whole retina peaked 6 h after photocoagulation in this model. …”
Publicado 2021
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10247por Han, Yoo Min, Koh, Jaemoon, Kim, Jee Hyun, Lee, Jooyoung, Im, Jong Pil, Kim, Joo Sung“…Real-time reverse transcription polymerase chain reaction was used to analyze the messenger RNA expression of the inflammatory cytokines interleukin (IL)-6 and IL-8. …”
Publicado 2021
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10248Functional lncRNA-miRNA-mRNA Networks in Response to Baicalein Treatment in Hepatocellular Carcinoma“…This work is aimed at exploring the functional long noncoding RNA (lncRNA)/microRNA (miRNA)/messenger RNA (mRNA) triplets in response to baicalein in hepatocellular carcinoma (HCC) cell to understand the mechanisms of baicalein in HCC. …”
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10249por Světlák, Miroslav, Linhartová, Pavla, Knejzlíková, Terezia, Knejzlík, Jakub, Kóša, Barbora, Horníčková, Veronika, Jarolínová, Kristýna, Lučanská, Klaudia, Slezáčková, Alena, Šumec, Rastislav“…We designed an 8-week online mindfulness-based program (eMBP) combining a face-to-face approach, text, audio, video components, and support psychotherapy principles with a unique intensive reminder system using the Facebook Messenger and Slack applications in two separate runs (N = 692). …”
Publicado 2021
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10250por Neaga, Alexandra, Bagacean, Cristina, Tempescul, Adrian, Jimbu, Laura, Mesaros, Oana, Blag, Cristina, Tomuleasa, Ciprian, Bocsan, Corina, Gaman, Mihaela, Zdrenghea, Mihnea“…MicroRNAs (miRNAs) have a role in the post-transcriptional regulation of gene expression, by impending translation and promoting degradation of messenger RNAs. They are important modulators of cellular pathways, playing major roles in normal hematopoietic differentiation. miRNA expression is significantly correlated with the prognosis of hematopoietic malignancies, including AML. …”
Publicado 2021
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10251“…A RNA immunoprecipitation sequencing (RIPseq) analysis performed on cells overexpressing RPSAP52 identified 40 messenger RNAs (mRNAs) enriched in Argonaute 2 (AGO2) immunoprecipitated samples. …”
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10252por Mohammadi-Nasrabadi, Fatemeh, Salmani, Yeganeh, Broumandnia, Nasrin, Esfarjani, Fatemeh“…Two online questionnaires were undertaken through WhatsApp Messenger among the 210 customers and 50 managers of restaurants. …”
Publicado 2021
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10253“…In the present study, the direct role of 1,25OHD on osteogenic differentiation and mineralization in chicken mesenchymal stem cells (cMSCs) derived from day-old broiler bones was investigated. cMSCs were treated with control media (C), osteogenesis media (OM), OM with 1, 5, 10, and 50 nM 1,25OHD, respectively. The messenger RNA (mRNA) samples were obtained at 24 and 48 h and 3 and 7 days to examine mRNA expression of key osteogenic genes [runt related transcription factor 2 (RUNX2), bone morphogenetic protein 2 (BMP2), collagen type I alpha 2 chain (COL1A2), bone gamma-carboxyglutamate protein (BGLAP), secreted phosphoprotein 1 (SPP1), and alkaline phosphatase (ALP)]. …”
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10254por Sugai, Tamotsu, Osakabe, Mitsumasa, Sugimoto, Ryo, Eizuka, Makoto, Tanaka, Yoshihito, Yanagawa, Naoki, Otsuka, Koki, Sasaki, Akira, Matsumoto, Takayuki, Suzuki, Hiromu“…Thus, we examined SCNAs and the expression of messenger RNAs (mRNAs) located at corresponding loci in colorectal neoplasia, a progression model of human neoplasm. …”
Publicado 2020
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10255“…Non-coding RNAs (ncRNAs) are newly discovered functional small RNA molecules that are different from messenger RNAs, which can be translated into a protein. …”
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10256por Gosavi, Siddharth, Sangamesh, Samarth, Ananda Rao, Amogh, Patel, Suman, Hodigere, Vishwakarma C“…This results in premature chain termination and eventually to lower amounts of the insulin receptor messenger ribonucleic acid (mRNA). Ultimately, the number and density of insulin receptors in the plasma membrane are smaller, making the cells resistant to insulin. …”
Publicado 2021
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10257“…Gene ontology analysis showed that the IL-23-regulated messenger ribonucleic acids (mRNAs) were related to positive regulation of leukocyte chemotaxis, chemokine-mediated signaling pathway and C-X-C chemokine receptors binding. …”
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10258por Montt-Guevara, Maria Magdalena, Finiguerra, Michele, Marzi, Ilaria, Fidecicchi, Tiziana, Ferrari, Amerigo, Genazzani, Alessandro D., Simoncini, Tommaso“…D-Chiro-Inositol (D-Chiro-Ins) is a secondary messenger in the insulin signaling pathway. D-Chiro-Ins modulates insulin secretion, the mitochondrial respiratory chain, and glycogen storage. …”
Publicado 2021
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10259por Wang, Xiao Jing, Carlson, Paula, Chedid, Victor, Maselli, Daniel B., Taylor, Ann L., McKinzie, Sanna, Camilleri, Michael“…METHODS: We measured by reverse transcription polymerase chain reaction messenger RNA (mRNA) expression of 78 genes (reflecting tight junction proteins, chemokines, innate immunity, ion channels, and transmitters) and 5 proteins (barrier, bile acid receptor, and ion exchanger) in terminal ileal mucosa from 11 patients with IBS-diarrhea (IBS-D), 17 patients with IBS-constipation (IBS-C), and 14 healthy controls. …”
Publicado 2021
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10260por Mahling, Ryan, Rahlf, Cade R., Hansen, Samuel C., Hayden, Matthew R., Shea, Madeline A.“…Voltage-gated sodium channels (Na(v)s) are tightly regulated by multiple conserved auxiliary proteins, including the four fibroblast growth factor homologous factors (FGFs), which bind the Na(v) EF-hand like domain (EFL), and calmodulin (CaM), a multifunctional messenger protein that binds the Na(V) IQ motif. The EFL domain and IQ motif are contiguous regions of Na(V) cytosolic C-terminal domains (CTD), placing CaM and FGF in close proximity. …”
Publicado 2021
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