“…BACKGROUND: Subcellular localization of messenger RNA (mRNAs) plays a pivotal role in the regulation of gene expression, cell migration as well as in cellular adaptation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…INTRODUCTION: Since the first COVID-19 messenger RNA vaccines became available globally for emergency or conditional use, post-marketing surveillance activities have been implemented for the monitoring of any adverse events that might arise in daily clinical practice and were not detected earlier during clinical trials. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Vector-based AZD1222 vaccine induced more frequently detectable specific CD4(+) responses in study participants across all cohorts (96%; 27 of 28), whereas fully messenger RNA-based vaccination schemes resulted in measurable CD4(+) cells in only 102 of 168 participants (61%; P < .0001). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…INTRODUCTION: Myocarditis has been recognized as a rare complication of coronavirus disease 2019 (COVID-19) messenger RNA (mRNA) vaccinations. The frequency of the event was reported 2-3 cases per million vaccinations. …”
Enlace del recurso
Enlace del recurso

“…The cellular processes mediating this calcification are complex, but calcium second messenger signaling, regulated in part by the ryanodine receptor (RyR), has been shown to play a role in a number of other fibrocalcific diseases. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…MATERIALS AND METHODS: We used TCR-dependent and allergen-specific cytokine secretion of human and mouse T cells, next generation messenger ribonucleic acid sequencing (RNA-Seq) and two different models of allergic airway inflammation to examine lead SMI-compounds. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this study, a layered multiomic approach including messenger RNA (mRNA) and microRNA (miRNA) sequencing was used to evaluate transcriptome-wide differences between type 1 VWD- and control-derived endothelial colony forming cells (ECFCs) during basal and stimulated VWF release. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Molecular biological characterizations demonstrated greater TNNT2 messenger RNA (mRNA) expression in the iPSCs-induced cardiomyocytes (iPS-CMs) than in the iPSCs. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: The results from the study demonstrated that S100A4, S100A10, and S100A13 may act as prognostic markers through overall survival (OS), disease-free survival (DFS) and tumor infiltrating immune cell enrichment and a prognostic S100 family gene model comprising S100A1–A4, S100A8, S100A10, S100A12, and S100A13 was identified. The messenger RNA (mRNA) expression of S100A1, S100A9, S100A14, and S100A7A was significantly different in HNSCC patients, together with a high mutation rate of the S100 family was found. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…However, the effect of the ceRNA network on breast cancer, especially the long non-coding RNA (lncRNA)-microRNA (miRNA)-messenger RNA (mRNA) regulatory network, has not been fully studied. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moreover, the high mutation rate of exportins in non-small cell lung cancer was 50.48%, and the largest proportion of mutations included high messenger RNA expression. The expression of exportins was significantly correlated with the infiltration of various immune cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Compared with C1 and C3, C2 had the lowest innate immune cell and adaptive immune cell infiltration scores; the lowest stromal score, immune score, and iconic immune checkpoint expression; and the highest expression of messenger RNA (mRNA) expression-based stemness indices (mRNAsi), DNA methylation-based stemness index (mDNAsi), and tumor mutational burden (TMB). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Forty‐one (26.6%) reported feeling very confident in counseling patients who primarily speak English about the evidence for messenger ribonucleic acid vaccination in pregnancy, and 36 (23%) reported feeling very confident in counseling patients who are not primarily English‐speaking. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The prognostic analysis, expression difference, and correlation analysis of messenger RNAs (mRNAs), lncRNAs, and miRNAs were carried out using the Gene Expression Profiling Interactive Analysis (GEPIA), Kaplan-Meier plotter, and Encyclopedia of RNA Interactomes (ENCORI). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common cancers and an important medical problem with poor prognosis. The role of messenger RNA (mRNA) has been broadly researched in the progression of different human cancers. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: Our results showed a significantly higher tendon-bone insertion histomorphological score in the training group, and the messenger RNA and protein expression levels of type II collagen (COL2A1), SOX9, and type X collagen (COL10A1) were significantly elevated. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Results: Bioinformatics analysis revealed that HIF-1α messenger RNA level was significantly different between septic and nonseptic patients (P < 0.05). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Two weeks after receiving the second SARS-CoV-2 vaccine (BNT162b2, Coronavirus Modified Uridine messenger RNA (mRNA) Vaccine, Pfizer), she developed fatigue and gradually worsened. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The aim was to compare Mb concentration, Mb messenger RNA (mRNA) expression levels and myonuclear content within muscle fibers of these elite cyclists with those of physically-active controls. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Inhalable messenger RNA (mRNA) has demonstrated great potential in therapy and vaccine development to confront various lung diseases. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso