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10841por Chen, Rui, Hollborn, Margrit, Grosche, Antje, Reichenbach, Andreas, Wiedemann, Peter, Bringmann, Andreas, Kohen, Leon“…Secretion of vascular endothelial growth factor (VEGF) was determined with enzyme-linked immunosorbent assay. Messenger ribonucleic acid levels were determined with real-time reverse transcription polymerase chain reaction. …”
Publicado 2014
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10842“…In contrast, the uniform messenger levels of FUL-like genes suggest they are involved in the development of all organs and their expression in the ovary suggests cell differentiation starts before pollination. …”
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10843“…Calcium is a ubiquitous second messenger in urinary bladder smooth muscle (UBSM). …”
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10844“…However, traditional protein-based methods do not permit the identification of all body fluids and tissues, and thus molecular based strategies for the conclusive identification of all forensically relevant biological fluids and tissues need to be developed. Messenger RNA (mRNA) profiling is an example of such a molecular-based approach. …”
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10845por Heck, Melanie Vanessa, Azizov, Mekhman, Stehning, Tanja, Walter, Michael, Kedersha, Nancy, Auburger, Georg“…During cell stress, the transcription and translation of immediate early genes are prioritized, while most other messenger RNAs (mRNAs) are stored away in stress granules or degraded in processing bodies (P-bodies). …”
Publicado 2014
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10846por Yu, Yi, Zhang, Xiaoyan, Hong, Shanshan, Zhang, Mingxing, Cai, Qingqing, Jiang, Wei, Xu, Congjian“…BACKGROUND: Among the pro-inflammatory lipid mediators, platelet-activating factor (PAF) is a major primary and secondary messenger that binds to the PAF-receptor (PAFR). Epidermal growth factor (EGF) is a polypeptide growth factor that binds to the EGF-receptor (EGFR). …”
Publicado 2014
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10847por Fabrick, Jeffrey A., Ponnuraj, Jeyakumar, Singh, Amar, Tanwar, Raj K., Unnithan, Gopalan C., Yelich, Alex J., Li, Xianchun, Carrière, Yves, Tabashnik, Bruce E.“…Seven of the eight disrupted alleles each produced two or more different transcript isoforms, which implicates alternative splicing of messenger RNA (mRNA). This represents the first example of alternative splicing associated with field-evolved resistance that reduced the efficacy of a Bt crop.…”
Publicado 2014
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10848por Aref, Ahmed M, Hoa, Neil T, Ge, Lisheng, Agrawal, Anshu, Dacosta-Iyer, Maria, Lambrecht, Nils, Ouyang, Yi, Cornforth, Andrew N, Jadus, Martin R“…The expression of tumor antigenic precursor proteins (TAPPs) messenger RNA was first screened by reverse transcriptase quantitative real‐time polymerase chain reaction. …”
Publicado 2014
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10849por Gildea, John J., Shah, Ishan T., Van Sciver, Robert, Israel, Jonathan A., Enzensperger, Christoph, McGrath, Helen E., Jose, Pedro A., Felder, Robin A.“…Here we used a novel D(5)R-selective antagonist (LE-PM436) and D(1)R or D(5)R-specific gene silencing to determine second messenger coupling pathways and heterologous receptor interaction between the two receptors. …”
Publicado 2014
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10850“…Transcript levels of the IFN-stimulated genes (ISGs) ISG12, ISG15, MX1, and MX2 were analyzed using quantitative reverse transcription-polymerase chain reaction. These messenger RNAs were up-regulated by rbIFN in a time- and concentration-dependent manner. …”
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10851por Wu, Shuang, Yu, Wenjun, Qu, Xiaoyan, Wang, Rong, Xu, Ji, Zhang, Qiguo, Xu, Jiaren, Li, Jianyong, Chen, Lijuan“…Argonaute 2 (AGO2) protein, a core component of the RNA-induced silencing complex (RISC), can directly bind to miRNAs and mediate target messenger RNA (mRNA) degradation. A previous study showed that AGO2 knockdown suppressed human umbilical vein endothelial cell (HUVEC) growth and tube formation. …”
Publicado 2014
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10852por Park, Jae Hyung, Lee, Jihei Sara, Ko, Young-Guk, Lee, Seung Hyun, Lee, Beom Seob, Kang, Seok-Min, Chang, Byung Cheol, Pak, Hui-Nam“…SUBJECTS AND METHODS: We analyzed the histology and messenger ribonucleic acid (mRNA) or protein expression associated with endothelial function and thrombogenesis in 33 human atrial appendage tissues (20 LA tissues, 13 RA tissues) taken from 25 patients {57.7±11.3 years old, 44% males, AF: sinus rhythm (SR)=17:8} with mitral valve disease. …”
Publicado 2014
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10853“…MicroRNAs (miRNAs) are small, noncoding RNA molecules that regulate post-transcriptional gene expression by base pairing with partially complementary sequences within target messenger RNAs (mRNAs). Although the target genes and the precise biological functions of individual miRNAs remain largely unknown, miRNAs have been implicated in diverse biological processes, including both normal and pathological states. …”
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10854
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10855por Dudás, József, Schartinger, Volker H., Romani, Angela, Schweigl, Gabriele, Kordsmeyer, Kristian, Marta, Patricia Irina, Url, Christoph, Kral, Florian, Riechelmann, Herbert“…ERCC1 protein synthesis was compared with cell cycle distribution using combined immunocytochemistry and flow cytometry. ERCC1 messenger RNA (mRNA) and protein expression was investigated in normoxic and hypoxic conditions in Detroit 562 cells. …”
Publicado 2014
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10856por Müller, Sören“…MicroRNAs (miRNAs) are a class of ncRNAs that exert their function together with argonaute proteins by post-transcriptional gene silencing of messenger RNAs (mRNAs). Several studies provide evidence for alterations in miRNA expression in patients with neurodegenerative diseases. …”
Publicado 2014
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10857por Seemampillai, Borggia, Germack, Renee, Felkin, Leanne E., McCormack, Ann, Rose, Marlene L.“…Hsp-27tg hearts expressed significantly more messenger RNA (mRNA) markers of CD14+ monocytes at day 2 and less mRNA markers of CD3+ and CD8+T cells at day 5 compared with LCs. …”
Publicado 2014
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10858por Shrikrishna, Dinesh, Tanner, Rebecca J., Lee, Jen Y., Natanek, Amanda, Lewis, Amy, Murphy, Patrick B., Hart, Nicholas, Moxham, John, Montgomery, Hugh E., Kemp, Paul R., Polkey, Michael I., Hopkinson, Nicholas S.“…No significant between-group differences were observed in the primary end points of quadriceps endurance half-time (Δ0.5 s; 95% CI, −13.3-14.3; P = .94) or atrogin-1 messenger RNA expression (Δ−0.03 arbitrary units; 95% CI, −0.32-0.26; P = .84). …”
Publicado 2014
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10859por Yuan, Zhong-Yu, Dai, Ting, Wang, Shu-Sen, Peng, Rou-Jun, Li, Xing-Hua, Qin, Tao, Song, Li-Bing, Wang, Xi“…RESULTS: A total total of eight upregulated (CCL7, KISS1, MET, MMP7, NR4A3, ETV4, TIMP3, and TSHR) and three downregulated (ITGA7, SSTR, and MMP2) genes were identified between TNBC tissue and the luminal subtype of breast cancer tissue. ETV4 messenger ribonucleic acid was more than five-fold upregulated in TNBC tissue compared with the control tissue. …”
Publicado 2014
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10860“…In this paper we will review the evidence supporting the hypothesis that T1AM is a chemical messenger, namely that it is an endogenous substance able to interact with specific receptors producing significant functional effects. …”
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