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11081por Bussmann, Hendrik, Schulte-Michels, Janka, Bingel, Mara, Meurer, Fabio, Aatz, Stefan, Häberlein, Felix, Franken, Sebastian, Häberlein, Hanns“…For the determination of both the second messenger cAMP and the internalization of β(2)AR we have generated luciferase based reporter cell lines, which produce a cAMP-dependent luciferase in the cytosol and express β(2)AR with extracellular luciferase moiety in the plasma membrane. …”
Publicado 2020
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11082por Olstad, Ole Kristoffer, Gautvik, Vigdis Teig, LeBlanc, Marissa, Kvernevik, Karl Johnny, Utheim, Tor Paaske, Runningen, Anne, Wiig, Håvard, Kirkegaard, Camilla, Raastad, Truls, Reppe, Sjur, Gautvik, Kaare Morten“…CONCLUSIONS: Postmenopausal healthy and OP women have distinct muscle transcriptomes [messenger ribonucleic acids (mRNAs) and microRNAs] that are modulated by strength training, translating into key protein alterations and muscle fibre changes. …”
Publicado 2020
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11083por Yu, Fengyun, Zhang, Yu, Cheng, Chao, Wang, Wenqing, Zhou, Zisong, Rang, Wenliang, Yu, Han, Wei, Yaxun, Wu, Qijia, Zhang, Yi“…Poly(A) tails at the 3’ end of eukaryotic messenger RNAs control mRNA stability and translation efficiency. …”
Publicado 2020
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11084por Gu, Xuefeng, Jiang, Dongyang, Yang, Yue, Zhang, Peng, Wan, Guoqing, Gu, Wangxian, Shi, Junfeng, Jiang, Liying, Chen, Bing, Zheng, Yanjun, Liu, Dingsheng, Guo, Sufen, Lu, Changlian“…METHODS: A competing endogenous RNA (ceRNA) network was constructed by analyzing sample-matched messenger RNA (mRNA), long non-coding RNA (lncRNA), and microRNA (miRNA) expression profiles from MMD patients and control samples. …”
Publicado 2020
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11085“…Plasma Epstein-Barr virus viral capsid antigen was determined by immunoenzymatic techniques. RESULTS: Both the messenger RNA and protein expression levels of macrophage migration inhibitory factor were upregulated in nasopharyngeal carcinoma cell lines and nasopharyngeal carcinoma tissues. …”
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11086por Zheng, Jintao, He, Qiuming, Tang, Huajian, Li, Jiequan, Xu, Huiyu, Mao, Xiangming, Liu, Guoqing“…The expression of miR‐455‐5p or STRA6 messenger RNA (mRNA) was determined by quantitative real‐time polymerase chain reaction. …”
Publicado 2020
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11087por Zhang, Feng, Zeng, Liping, Cai, Qinming, Xu, Zihao, Liu, Ruida, Zhong, Haicheng, Mukiibi, Robert, Deng, Libin, Tang, Xiaoli, Xin, Hongbo“…A total of 1833 lncRNAs, 156 microRNAs (miRNAs), and 3443 messenger RNAs (mRNAs) were identified as differentially expressed (DE) using “DESeq2” package. …”
Publicado 2020
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11088por Zhang, Heng, Cao, Nengqi, Yang, Zhilong, Fang, Xingchao, Yang, Xinyu, Li, Hao, Hong, Zhi, Ji, Zhenling“…In accordance with the in vitro results, the levels of inflammatory cytokines such as interleukin 6 (IL-6), IL-1β, and tumor necrosis factor (TNF-α) in serum as well as messenger RNA (mRNA) expression in colon were obviously reduced in the bilobalide treated groups. …”
Publicado 2020
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11089por Zhang, Xiliang, Duan, Lian, Zhang, Yuxing, Zhao, Huibin, Yang, Xiaodong, Zhang, Chaojun“…Thereafter, expression levels of Fibulin-2 messenger RNA (mRNA) and protein were measured via quantitative real-time reverse transcription-polymerase chain reaction and western blotting, respectively. …”
Publicado 2020
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11090por Stokes, Simon M., Burns, Teresa A., Watts, Mauria R., Bertin, François‐René, Stefanovski, Darko, Medina‐Torres, Carlos E., Belknap, James K., van Eps, Andrew W.“…RESULTS: Compared to AMB, lamellar messenger ribonucleic acid (mRNA) concentrations of CXCL6 (P =.02), CXCL8 (P = .008), IL‐6 (P = .008), IL‐1β (P = .008), IL‐11 (P = .008), and cyclooxygenase‐2 (P = .008) were decreased in CDH. …”
Publicado 2020
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11091por Wood, Katherine A., Rowlands, Charlie F., Thomas, Huw B., Woods, Steven, O’Flaherty, Julieta, Douzgou, Sofia, Kimber, Susan J., Newman, William G., O’Keefe, Raymond T.“…The craniofacial developmental disorder Burn-McKeown Syndrome (BMKS) is caused by biallelic variants in the pre-messenger RNA splicing factor gene TXNL4A/DIB1. The majority of affected individuals with BMKS have a 34 base pair deletion in the promoter region of one allele of TXNL4A combined with a loss-of-function variant on the other allele, resulting in reduced TXNL4A expression. …”
Publicado 2020
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11092“…Using real-time polymerase chain reaction, we investigated the aldehyde dehydrogenase 3B1 messenger RNA in 20 lung adenocarcinoma and paired normal lung tissues. …”
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11093por Pan, Ling, Lu, Yuehong, Li, Zhanhua, Tan, Yuping, Yang, Hongmei, Ruan, Ping, Li, Ruixiang“…In addition, the protein or messenger ribonucleic acid expression levels of phosphorylated NF-κB (p65), caspase-3, and caspase-9 were upregulated, whereas Bax and Bcl-2 were downregulated. …”
Publicado 2020
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11094“…The potential for HNF4α to regulate SBP1 expression was supported by data indicating that HNF4α inhibition resulted in a dose‐response increase in the levels of SBP1 messenger RNA and protein, identifying HNF4α as a novel negative regulator of SBP1 expression in prostate cancer cells. …”
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11095por Wang, Xiaoqing, Wu, Xiangyu, Li, Tianyou, Cui, Mingyu, Zhu, Lichao, Wang, Gang, Guo, Feng“…In this study, RNA sequencing data were obtained to identify differentially expressed messenger RNAs (mRNAs), long noncoding RNAs (lncRNAs), and microRNAs (miRNAs) between RTK samples and normal samples. …”
Publicado 2020
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11096por Chao, Xu, Jia, Yong, Feng, Xuesong, Wang, Guoquan, Wang, Xiaoping, Shi, Hailong, Zhao, Fei, Jiang, Chao“…Background: Adenylyl cyclase type 9 (ADCY9) modulates signal transduction by producing the second messenger cyclic AMP. It has been reported that ADCY9 gene polymorphisms were associated with cancer development. …”
Publicado 2020
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11097“…The present study was to develop a new prognostic signature by integrating long noncoding RNAs (lncRNAs) and messenger RNAs (mRNAs) and evaluate its prognostic performance. …”
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11098“…Zinc ions (Zn(2+)) are important messenger molecules involved in various physiological functions. …”
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11099“…Quantitative real‐time polymerase chain reaction was performed to determine the expression of microRNA (miR) and messenger RNA, and western blot analysis was conducted to examine the protein levels. …”
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11100por Shi, Yi, Ren, Jianhua, Zhuang, Ze, Zhang, Wenhui, Wang, Zhe, Liu, Yuangao, Li, Jinze, Liang, Tangzhao, He, Ronghan, Wang, Kun“…Increasing evidence indicates that long noncoding RNAs (lncRNAs), which function as competing endogenous RNAs (ceRNAs) that sponge microRNAs (miRNAs) and messenger RNAs (mRNAs), play a pivotal role in the pathogenesis and progression of cancers. …”
Publicado 2020
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