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11121por Wang, Wen-Ling, Hong, Guan-Ci, Chien, Peng-Ju, Huang, Yu-Hao, Lee, Hsueh-Te, Wang, Po-Hui, Lee, Yueh-Chun, Chang, Wen-Wei“…Here, we investigated the biological function of TRIB3 in EC. We found that the messenger RNA (mRNA) expression level of TRIB3 was significantly and positively correlated with shorter overall survival of EC patients in The Cancer Genome Atlas database. …”
Publicado 2020
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11122por Li, Yangyang, Zhou, Ying, Zhao, Minghui, Zou, Jing, Zhu, Yuxiao, Yuan, Xuewen, Liu, Qianqi, Cai, Hanqing, Chu, Cong-Qiu, Liu, Yu“…Bioinformatic tools were adopted to predict putative microRNAs (miRNAs) sponged by these validated circRNAs and their downstream messenger RNAs (mRNAs). Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses were performed to gain further insights into T1DM pathogenesis. …”
Publicado 2020
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11123“…The BTV viral load and the expression of cytokine messenger RNA (mRNA) in PBMCs were measured by fluorescence-based real-time reverse-transcription PCR (qRT-PCR). …”
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11124por Wang, Junxiu, Li, Tingting, Deng, Sufang, Ma, Enbo, Zhang, Jianzhen, Xing, Shuping“…It has been extensively studied in yeast and mammals and has been shown to be involved in messenger ribonucleoprotein assembly, mRNA storage, and decay, as well as in miRNA-mediated gene silencing. …”
Publicado 2021
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11125por Gopalan, Venkatesh, Yaligar, Jadegoud, Michael, Navin, Kaur, Kavita, Anantharaj, Rengaraj, Verma, Sanjay Kumar, Sadananthan, Suresh Anand, Le, Giang Thi Thu, Goh, Jorming, Velan, S. Sendhil“…HFD+Exercise animals had significantly lower leptin (P=0.0004), triglycerides (P=0.007), homeostatic model assessment of insulin resistance (HOMA-IR; P=0.065), intramyocellular lipids (IMCLs; P=0.003), intrahepatic lipids (IHLs; P<0.0001), body fat% (P=0.001), subcutaneous adipose tissue (SAT; P<0.0001), visceral adipose (P<0.0001) and total fat mass (P<0.0001), relative to sedentary HFD-fed animals, despite only modestly lower bodyweight. Messenger RNA (mRNA) expression of inflammatory markers Interleukin 6 (IL6) and Tumor necrosis factor α (TNFα) were also reduced with aerobic exercise in skeletal muscle. …”
Publicado 2021
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11126por Tan, Jianye, Liang, Haofeng, Yang, Bingsheng, Zhu, Shuang, Wu, Guofeng, Li, Lutao, Liu, Zhengwei, Li, Lin, Qi, Weizhong, Li, Sijing, Lin, Lijun“…We categorized transcriptome data into metastasis and nonmetastasis groups, and 400 differential RNAs (230 messenger RNAs (mRNAs) and 170 long noncoding RNAs (lncRNAs)) were obtained by the edgeR package. …”
Publicado 2021
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11127“…METHODS: The methods employed in the study included public dataset analysis, western blot, quantitative real-time PCR (qRT-PCR), cell count kit-8 (CCK8) assay, colony formation assay, flow cytometric analysis, RNA immunoprecipitation (RIP), messenger RNA (mRNA) stability assay, QKI overexpression and knockdown, and Ras p21 protein activator 1 (RASA1) knockdown. …”
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11128por Ke, Xingrao, Xing, Bohan, Dahl, Mar Janna, Alvord, Jeremy, McKnight, Robert A., Lane, Robert H., Albertine, Kurt H.“…We tested the hypotheses that NRS leads to greater levels of IGF1 messenger RNA (mRNA) variants and distinct epigenetic profile along the IGF1 gene locus in the hippocampus compared to IMV. …”
Publicado 2021
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11129por Frick, Adrian, Khare, Vineeta, Jimenez, Kristine, Dammann, Kyle, Lang, Michaela, Krnjic, Anita, Gmainer, Christina, Baumgartner, Maximilian, Mesteri, Ildiko, Gasche, Christoph“…Increased β-catenin messenger RNA and cytoplasmic accumulation indicated aberrant Wnt signaling. …”
Publicado 2020
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11130por Hryniewicz-Jankowska, Anita, Wierzbicki, Jaroslaw, Tabola, Renata, Stach, Kamilla, Sossey-Alaoui, Khalid, Augoff, Katarzyna“…Using real-time polymerase chain reaction (PCR) and gelatin zymography, we found that MLN4924 inhibited expression and activity of MMP9 at the messenger RNA (mRNA) and protein levels in both resting cells and cells stimulated with TNF-α, and this inhibition was closely related to impaired cell migration. …”
Publicado 2021
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11131“…It plays a pivotal role in the biosynthesis of glycosphingolipids, primarily by way of serving as a precursor to the majority of its higher homolog sub-families such as gangliosides, sulfatides, fucosylated-glycosphingolipids and complex neutral glycosphingolipids—some of which confer “second-messenger” and receptor functions. LacCer is an integral component of the “lipid rafts,” serving as a conduit to transduce external stimuli into multiple phenotypes, which may contribute to mortality and morbidity in man and in mouse models of human disease. …”
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11132“…BACKGROUND: Previous studies have demonstrated associations between cardiovascular disease and the expression of various messenger RNAs (mRNAs), microRNAs (miRNAs), and long non-coding RNAs (lncRNAs). …”
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11133por Mosha, Jacklin F., Kulkarni, Manisha A., Messenger, Louisa A., Rowland, Mark, Matowo, Nancy, Pitt, Catherine, Lukole, Eliud, Taljaard, Monica, Thickstun, Charles, Manjurano, Alphaxard, Mosha, Franklin W., Kleinschmidt, Immo, Protopopoff, NatachaEnlace del recurso
Publicado 2021
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11134por Ninić, Ana, Bojanin, Dragana, Sopić, Miron, Mihajlović, Marija, Munjas, Jelena, Milenković, Tatjana, Stefanović, Aleksandra, Vekić, Jelena, Spasojević-Kalimanovska, Vesna“…TGF-β1 and transmembrane full-length RAGE (flRAGE) messenger ribonucleic acid (mRNA) levels in peripheral blood mononuclear cells (PBMC) were obtained by quantitative polymerase chain reaction (qPCR) method. …”
Publicado 2021
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11135por Ansari, Mohd Nazam, Rehman, Najeeb Ur, Karim, Aman, Imam, Faisal, Hamad, Abubaker M.“…The nephrotoxicity was measured with various parameters such as kidney function markers, oxidative stress markers (glutathione (GSH) and malondialdehyde (MDA)), and messenger ribonucleic acid (mRNA) expression levels of inflammatory factors. …”
Publicado 2021
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11136“…MCF7-TamR cells overexpress messenger RNAs (mRNAs) for metallothionein 2A and ferritin heavy chain, and they are re-sensitized to Tam by inhibition of autophagy. …”
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11137por Mili, Most Israt Jahan, Ahmed, Md Kawser, Masud-Ul-Alam, Md, Hasnain, Md, Khan, Md. Ashif Imam, Loodh, Rupak, Hasan, Abdullah-Al, Belayet Hossain, Kazi, Al Nahian, Sultan“…Sediment was collected by Van Veen Grab sampler with built-in messenger. Water samples were analyzed following the standard procedure in the laboratory to access in-situ data. …”
Publicado 2021
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11138por Barilli, Amelia, Visigalli, Rossana, Ferrari, Francesca, Borsani, Giuseppe, Dall'Asta, Valeria, Rotoli, Bianca Maria“…In this tissue model, the incubation with flagellin is associated with the upregulation of messenger RNAs (mRNAs) for the chemokine IL-8 and for the cytokines IL-6 and interleukin-1β (IL-1β); as for the latter, a marked secretion in the extracellular medium was also observed due to the concomitant activation of caspase-1. …”
Publicado 2021
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11139RNA-Seq analysis reveals critical transcriptome changes caused by sodium butyrate in DN mouse modelspor Yang, Hansen, Zhang, Zheng, Peng, Rui, Zhang, Luyu, Liu, Handeng, Wang, Xinyi, Tian, Yiting, Sun, Yan“…Whole-transcriptome analysis was performed by RNA sequencing (RNA-Seq) to evaluate the profiling of long non-coding RNAs (lncRNAs) and messenger RNAs (mRNAs). Bioinformatics analysis was performed to predict the potential NaB-related lncRNAs and genes in DN. …”
Publicado 2021
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11140por Zhou, Jingwen, Zhang, Xiaolong, Wan, Lingfeng, Yu, Jun, Li, Tianci, Lu, Ziyu, Fang, Nanyuan, Sun, Lixia, Ye, Fang“…The viability of LX-2 cells was evaluated with MTT assay. Relative messenger RNA (mRNA) expression of representative extracellular matrix (ECM) components was detected with real-time quantitative polymerase chain reaction (RT-qPCR). …”
Publicado 2021
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