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11641por Bello-Chavolla, Omar Yaxmehen, Antonio-Villa, Neftali Eduardo, Valdés-Ferrer, Sergio Iván, Fermín-Martínez, Carlos A., Fernández-Chirino, Luisa, Vargas-Vázquez, Arsenio, Ramírez-García, Daniel, Mancilla-Galindo, Javier, Kammar-García, Ashuin, Ávila-Funes, José Alberto, Zúñiga-Gil, Clemente Humberto, García-Grimshaw, Miguel, Ceballos-Liceaga, Santa Elizabeth, Carbajal-Sandoval, Guillermo, Montes-González, José Antonio, Zaragoza-Jiménez, Christian Arturo, García-Rodríguez, Gabriel, Cortés-Alcalá, Ricardo, Reyes-Terán, Gustavo, López-Gatell, Hugo, Gutiérrez-Robledo, Luis Miguel“…METHODS: Retrospective analysis of a COVID-19 surveillance system to assess the VE of the BNT162b2, messenger RNA (mRNA)-12732, Gam-COVID-Vac, Ad5-nCoV, Ad26.COV2.S, ChAdOx1, and CoronaVac vaccines against SARS-CoV-2 infection, COVID-19 hospitalization, and death in Mexico. …”
Publicado 2023
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11642por Norris, Jordan E., Schmitt, Lauren M., De Stefano, Lisa A., Pedapati, Ernest V., Erickson, Craig A., Sweeney, John A., Ethridge, Lauren E.“…INTRODUCTION: Fragile X Syndrome (FXS) is rare genetic condition characterized by a repeat expansion (CGG) in the Fragile X messenger ribonucleoprotein 1 (FMR1) gene where individuals with greater than 200 repeats are defined as full mutation. …”
Publicado 2023
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11643por Li, Xintong, Tang, Lin, Chen, Qin, Cheng, Xumin, Liu, Yiqiu, Wang, Cenzhu, Zhu, Chengjun, Xu, Kun, Gao, Fangyan, Huang, Jinyi, Wang, Runtian, Guan, Xiaoxiang“…Suppression of MYC in TNBC caused a reduction in the levels of both PD-L1 messenger RNA and protein. In addition, antitumor immune response was enhanced in the TNBC cancer xenograft mouse model with suppression of MYC by CDK7 inhibitor THZ1. …”
Publicado 2022
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11644por Jabarpour, Masoome, Aleyasin, Ashraf, Nashtaei, Maryam Shabani, Lotfi, Sara, Amidi, Fardin“…After the intervention, ASX led to a considerable reduction in the expression levels of 78-kDa glucose-regulated protein (GRP78), CCAAT/enhancer-binding protein homologous protein (CHOP), and X-box-binding protein 1 compared to the placebo group, though the reduction in the messenger RNA (mRNA) expression level of activating transcription factor 6 was not statistically significant. …”
Publicado 2023
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11645por Shahnazari, Mina, Afshar, Saeid, Emami, Mohammad Hassan, Amini, Razieh, Jalali, Akram“…The regulation and interaction among different cancer-promoting molecules, including messenger RNAs (mRNAs) and micro RNAs (miRNAs) in CRC and its progression, were the aim we pursued in this study. …”
Publicado 2023
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11646“…We found an increase in the DNA methylation writers DNMT1, DNMT3A and DNMT3B messenger RNA (mRNA) and a decrease in the reader UHRF1 mRNA in AD samples across three brain regions whilst the DNA erasers GADD45B and AICDA showed changes in mRNA abundance within neuropathological load groupings. …”
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11647por Yoshioka, Yuya, Kobiyama, Kouji, Hayashi, Tomoya, Onishi, Motoyasu, Yanagida, Yosuke, Nakagawa, Takayuki, Hashimoto, Masayuki, Nishinaka, Anri, Hirose, Jun, Asaoka, Yoshiji, Tajiri, Minako, Hayata, Atsushi, Ishida, Satoru, Omoto, Shinya, Nagira, Morio, Ishii, Ken J.“…Furthermore, S-268019-b containing A-910823 adjuvant produced similar results even when given as a booster dose following primary administration of a lipid nanoparticle-encapsulated messenger RNA (mRNA-LNP) vaccine. Preparation of modified A-910823 adjuvants to identify which components of A-910823 play a role in driving the adjuvant effect and detailed evaluation of the immunological characteristics induced by each adjuvant showed that the induction of humoral immunity and Tfh and GCB cell induction in A-910823 were dependent on α-tocopherol. …”
Publicado 2023
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11648“…The differential DNA methylation of the selected genes was validated via direct bisulfite sequencing and analysis of their messenger ribonucleic acid (mRNA) levels using quantitative reverse transcription polymerase chain reaction (qRT-PCR). …”
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11649“…Zinc-induced apoptosis was identified by Hoechst nuclear staining and flow cytometry analysis. TR3 messenger RNA (mRNA) expression levels were detected by real time-quantitative polymerase chain reaction (PCR). …”
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11650por Huang, Yiyao, Abdelgawad, Ahmed, Turchinovich, Andrey, Queen, Suzanne, Abreu, Celina Monteiro, Zhu, Xianming, Batish, Mona, Zheng, Lei, Witwer, Kenneth W.“…Using brain tissue and bdEVs from the simian immunodeficiency virus (SIV) model of HIV disease, we profiled messenger RNAs (mRNAs), microRNAs (miRNAs), and circular RNAs (circRNAs), seeking to identify possible networks of RNA interaction in SIV infection and neuroinflammation. …”
Publicado 2023
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11651“…Recombinant (r)proteins 3 and 4 were shown to induce immunodominant Th1 and Th2 immune responses characterised by the secretion of effector cytokines IFN-γ and IL-4 in addition to differential messenger ribonucleic acid (mRNA) expression of tumour necrosis factor (TNF), IL-2, IL-1, IL-18, IL-10, transforming growth factor (TGF), granulocyte-macrophage colony-stimulating factor (GM-CSF) and inducible nitric oxide synthase (iNOS). …”
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11652“…Cyclic di-GMP (c-di-GMP) is a second messenger that controls the transition between planktonic and sessile lifestyles, in response to environmental cues. …”
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11653“…RESULTS: ATP induced the increased expression of IL-1β, IL-6 and TNF-α at the level of messenger RNA (mRNA). ATP-evoked increase in IL-1β, IL-6 and TNF-α mRNA expression was inhibited by the P2X4 receptor antagonist A-740003 or P2X7 receptor antagonist PSB-12062, respectively. …”
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11654por Kim, Janghyun, Lee, Bora, Lee, Sungsu, Kim, Joon-Tae, Kim, Byeong C., Cho, Hyong-Ho“…In this study, we analyzed the common expression profiles of messenger RNA (mRNA) and lncRNA through ARHL-related RNA-sequencing datasets. …”
Publicado 2023
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11655“…Myeloid differentiation factor 88 (MyD88) is a common intermediate messenger for NF-κB activation by inducers. In the present study, the level of MyD88 in PDAC was detected using a public database and a tissue chip. …”
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11656por Cheah, Menghon, Cheng, Yuyan, Petrova, Veselina, Cimpean, Anda, Jendelova, Pavla, Swarup, Vivek, Woolf, Clifford J., Geschwind, Daniel H., Fawcett, James W.“…This research uses profiling of messenger RNAs in the regenerating sensory neurons to discover which mechanisms are activated. …”
Publicado 2023
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11657por Yao, Weijie, Yao, Yanrong, He, Wen, Zhao, Chengsi, Liu, Di, Wang, Genwang, Wang, Zuozheng“…After silencing PABPC1, messenger RNA sequencing and Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were performed. …”
Publicado 2023
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11658por Gao, Yuan, Song, Weiguo, Hao, Fei, Duo, Lei, Zhe, Xiaoshu, Gao, Chunyan, Guo, Xudong, Liu, Dongjun“…Herein, we systematically investigated a competing endogenous RNA (ceRNA) regulatory network mediated by circular RNAs (circRNAs), microRNAs (miRNAs), and messenger RNAs (mRNAs) in skin samples of cashmere goat embryos, using whole-transcriptome sequencing technology. …”
Publicado 2023
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11659por Hussain, Muhammad Zahid, Haris, Muhammad Shahbaz, Rizwan, Muhammad, Ashraf, Nida Sarosh, Arshad, Maryam, Mahjabeen, Ishrat“…Exosomal cargo molecules contain proteins and miRNAs. miRNAs are small non-coding RNA fragments involved in the reduction of final protein output by destabilizing or suppressing the translation of target messenger RNA (mRNA). This deregulation of the protein due to miRNAs ultimately accelerates the process of disease pathogenesis. …”
Publicado 2023
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11660por Yovogan, Boulais, Adoha, Constantin J., Akinro, Bruno, Accrombessi, Manfred, Dangbénon, Edouard, Sidick, Aboubakar, Ossè, Razaki, Padonou, Gil G., Messenger, Louisa A., Fassinou, Arsène, Sagbohan, Hermann W., Agbangla, Clément, Djènontin, Armel, Odjo, Esdras M., Ngufor, Corine, Cook, Jackie, Protopopoff, Natacha, Sovi, Arthur, Akogbéto, Martin C.Enlace del recurso
Publicado 2023
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