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12121por Hwang, Sung Jin, Blair, Peter J., Rock, Jason, Pardo, David, Sanders, Kenton M., Ward, Sean M.“…Motor neurons innervate these three cell types in the SIP syncytium, and receptors, second messenger pathways, and ion channels in these cells mediate postjunctional responses. …”
Publicado 2016
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12122por Ma, Xuepo, Zhu, Ying, Huang, Yufei, Tegeler, Tony, Gao, Shou-Jiang, Zhang, Jianqiu“…METHOD: We integrate several (18)O/(16)O data processing algorithms that we published recently and identify the messenger RNAs of downregulated proteins as potential targets in KSHV miR-transfected human embryonic kidney 293T cells. …”
Publicado 2016
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12123por Tungu, Patrick, Messenger, Louisa A., Kirby, Matthew J., Sudi, Wema, Kisinza, William, Rowland, MarkEnlace del recurso
Publicado 2016
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12124“…This problem becomes a challenge due to the lack of deep knowledge about the biological systems and unfamiliarity of conservative characteristics in the messenger RNA (mRNA). Therefore, it is fundamental to research for computational methods aiming to help the patterns discovery for identification of the Translation Initiation Sites (TIS). …”
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12125por Malima, Robert, Emidi, Basiliana, Messenger, Louisa A., Oxborough, Richard M., Batengana, Bernard, Sudi, Wema, Weston, Sophie, Mtove, George, Mugasa, Joseph P., Mosha, Franklin W., Rowland, Mark W., Kisinza, WilliamEnlace del recurso
Publicado 2017
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12126por Liu, Jiao, Li, Guang, Xie, Wen-Jie, Wang, Lu, Zhang, Rui, Huang, Ke-Sheng, Zhou, Qing-Shan, Chen, De-Chang“…HK-2 cells were stimulated with 100 ng/ml of LPS for different durations to determine the effects of LPS on SP-A and toll-like receptor 4 (TLR4) messenger RNA (mRNA) expression, as well as phosphorylation of mitogen-activated/extracellular signal-regulated kinase (MEK) 1, extracellular signal-regulated kinase 1/2 (ERK1/2), p38 mitogen-activated protein kinase (p38MAPK), and nuclear factor-kappa B (NF-κB) inhibitor-alpha (IkB-α). …”
Publicado 2017
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12127“…CONCLUSION: A better understanding of those genes with undefined function and simultaneous quantitation of both miRNAs and messenger RNAs are needed to fully understand CIU disease.…”
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12128por Rui, Yehua, Tong, Lingxia, Cheng, Jinbo, Wang, Guiping, Qin, Liqiang, Wan, Zhongxiao“…Objective: We aimed to investigate the therapeutic use of RA as an anti-obesity agent by measuring its effects on adipogenesis, lipolysis, and messenger RNA (mRNA) expression of major adipokines in 3T3-L1 adipocytes; and its effects on lipopolysaccharide (LPS)-induced tumor necrosis factor-α (TNF-α) secretion in macrophages and inflammatory mediators in 3T3-L1 adipocytes incubated with macrophage-conditioned medium (MCM). …”
Publicado 2017
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12129por Turner, Natalie, Forcato, Mattia, Nuzzo, Simona, Malorni, Luca, Bicciato, Silvio, Di Leo, Angelo“…METHODS: ConSigs were constructed based on five steps required for anthracycline function: drug penetration, nuclear topoisomerase IIα (topoIIα) protein location, increased topoIIα messenger RNA (mRNA) expression, apoptosis induction, and immune activation measured by, respectively, HIF1α or SHARP1 signature, LAPTM4B mRNA, topoIIα mRNA, Minimal Gene signature or YWHAZ mRNA, and STAT1 signature. …”
Publicado 2015
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12130“…Finally, we performed a transcriptome-wide mapping of Argonaute footprints by high-throughput sequencing of RNA isolated by cross-linking immunoprecipitation (Ago HITS-CLIP) to empirically characterize targeting relationship between estrogen-responsive miRNAs and their messenger RNA (mRNA) targets. RESULTS: In this study, we demonstrated that the neonatal hypothalamic miRNA environment has robust sex differences and is dynamically responsive to estrogen. …”
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12131“…After functional mandibular deviation, HDC protein and messenger ribonucleic acid (mRNA) levels on the ipsilateral sides of the chewing muscle and splenius increased significantly. …”
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12132“…Myocardial infarct size (IS), cardiac troponin I level, and heart function were measured. The protein and messenger RNA levels of LTCCs, RyR2, and NCX1 were determined. …”
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12133por Anaparti, Vidyanand, Smolik, Irene, Meng, Xiaobo, Spicer, Victor, Mookherjee, Neeloffer, El-Gabalawy, Hani“…Expression of 35 selected relevant miRNAs, as well as associated downstream messenger RNA (mRNA) targets of miR-103a-3p, was determined by qRT-PCR. …”
Publicado 2017
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12134por Messenger, Louisa A., Shililu, Josephat, Irish, Seth R., Anshebo, Gedeon Yohannes, Tesfaye, Alemayehu Getachew, Ye-Ebiyo, Yemane, Chibsa, Sheleme, Dengela, Dereje, Dissanayake, Gunawardena, Kebede, Estifanos, Zemene, Endalew, Asale, Abebe, Yohannes, Mekonnen, Taffese, Hiwot Solomon, George, Kristen, Fornadel, Christen, Seyoum, Aklilu, Wirtz, Robert A., Yewhalaw, DelenasawEnlace del recurso
Publicado 2017
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12135“…In total, 147 lncRNAs and 1382 circRNAs were predicted to combine with 148 common miRNAs and compete for miRNA binding sites with 744 messenger RNAs. These mRNAs were predicted to significantly participate in osteoblast differentiation, the MAPK pathway, the Wnt pathway and the signaling pathways regulating pluripotency of stem cells. …”
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12136“…Eburicoic acid, Feno, and Metf displayed both enhanced expression levels of phospho-AMPK and membrane expression levels of GLUT4 in the skeletal muscle of HFD-fed mice to facilitate glucose uptake with consequent enhanced hepatic expression levels of phospho-AMPK in the liver and phosphorylation of the transcription factor forkhead box protein O1 (FOXO1) but decreased messenger RNA (mRNA) of phosphenolpyruvate carboxykinase (PEPCK) to inhibit hepatic glucose production; resulting in lowered blood glucose levels. …”
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12137por Kang, Dae Joong, Hylemon, Phillip B, Gillevet, Patrick M, Sartor, R. Balfour, Betrapally, Naga S., Kakiyama, Genta, Sikaroodi, Masoumeh, Takei, Hajime, Nittono, Hiroshi, Zhou, Huiping, Pandak, William M., Yang, Jing, Jiao, Chunhua, Li, Xiaojiaoyang, Lippman, H. Robert, Heuman, Douglas M., Bajaj, Jasmohan S.“…Both hepatic Cyp7a1 and sterol 12α‐hydroxylase (Cyp8b1) messenger RNA (mRNA) levels were significantly induced in the Alc‐Hum and Ctrl‐Hum mice but not in the Cirr‐Hum mice or GF mice. …”
Publicado 2017
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12138por Akbari, Hakimeh, Eftekhar Vaghefi, Seyed Hassan, Shahedi, Abbas, Habibzadeh, Victoria, Mirshekari, Tooraj Reza, Ganjizadegan, Aboozar, Mollaei, Hamidreza, Ahmadi, Meysam, Nematollahi-Mahani, Seyed Noureddin“…The developmental stages of parthenote embryos in hUCM versus α-MEM were as follows: 2–4 cell (89.45% vs. 66.00%, respectively), 4–8 cell (44.31% vs. 29.11%, respectively), morula (12.27% vs. 2.63%, respectively), and blastocysts (2.5% vs. 0%, respectively). The messenger RNA (mRNA) expression levels of BCL2, BAX and SOD were significantly different (p < 0.05) between the matured IVM oocytes. …”
Publicado 2017
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12139por Lyu, Qiang, Zhang, Zi-Bin, Fu, Song-Jun, Xiong, Liu-Lin, Liu, Jing, Wang, Ting-Hua“…Seven days after transplantation, oligodendrocytes 2 (Olig2) and myelin basic protein (MBP) were detected by immunohistochemistry (IHC) and Western blot (WB), and long noncoding RNAs (lncRNAs) and messenger RNAs (mRNAs) were screened by microarray technology. …”
Publicado 2017
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12140por Johnston, Zoe C., Bellingham, Michelle, Filis, Panagiotis, Soffientini, Ugo, Hough, Denise, Bhattacharya, Siladitya, Simard, Marc, Hammond, Geoffrey L., King, Peter, O’Shaughnessy, Peter J., Fowler, Paul A.“…METHODS: This was an observational study of steroids, messenger RNA transcripts and proteins in adrenals from up to 109 second trimester fetuses (11 weeks to 21 weeks) at the Universities of Aberdeen and Glasgow. …”
Publicado 2018
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