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12241por Xie, Feng, Zhang, Donglei, Qian, Xiaoqing, Wei, Huabing, Zhou, Lihuang, Ding, Chunyong, Pan, Wenbiao, Ye, Qing“…We performed microRNA (miRNA) and messenger RNA (mRNA) expression analysis to identify differentially expressed genes (DEGs). …”
Publicado 2022
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12242por Zheng, Hui, Qiu, Zhihuang, Chai, Tianci, He, Jian, Zhang, Yuling, Wang, Chaoyun, Ye, Jianqiang, Wu, Xiaohui, Li, Yumei, Zhang, Li, Chen, Liangwan“…METHODS: Through the statistical analysis, we determined the proportion of glycosylated hemoglobin (HbA1c) abnormalities (HbA1c > 5.7) in people with acute thoracic aortic dissection (ATAD) and compared the difference of messenger RNA (mRNA) and protein expression of GluT1 in the thoracic aorta of normal people and those with ATAD to find evidence that IR is a causative factor in AD. …”
Publicado 2022
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12243por Frasca, Angelisa, Pavlidou, Efterpi, Bizzotto, Matteo, Gao, Yunan, Balestra, Dario, Pinotti, Mirko, Dahl, Hans Atli, Mazarakis, Nicholas D., Landsberger, Nicoletta, Kinali, Maria“…Reverse transcriptase PCR was used to analyze whether the identified nucleotide variant affects messenger RNA stability and/or splicing. The X chromosome inactivation pattern was analyzed determining the DNA methylation status of the androgen receptor (AR) gene and by sequencing of expressed alleles. …”
Publicado 2022
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12244por Adeola, Henry Ademola, Bello, Ibrahim O., Aruleba, Raphael Taiwo, Francisco, Ngiambudulu M., Adekiya, Tayo Alex, Adefuye, Anthonio Oladele, Ikwegbue, Paul Chukwudi, Musaigwa, Fungai“…The promising application of different LB approaches using various downstream analyses such as released circulating tumor cells (CTCs), cell free DNA (cfDNA), microRNA (miRNA), messenger RNA (mRNA), and salivary exosomes were discussed. …”
Publicado 2022
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12245por Lasagna, A., Bergami, F., Lilleri, D., Percivalle, E., Quaccini, M., Alessio, N., Comolli, G., Sarasini, A., Sammartino, J.C., Ferrari, A., Arena, F., Secondino, S., Cicognini, D., Schiavo, R., Lo Cascio, G., Cavanna, L., Baldanti, F., Pedrazzoli, P., Cassaniti, I.“…We prospectively evaluated the immunogenicity of the third dose of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) BNT162b2 messenger RNA vaccine in cancer patients undergoing active treatment. …”
Publicado 2022
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12246por Zhang, Teng, Zhao, Wei, Ren, Tengzhou, Chen, Jie, Chen, Zhiwei, Wang, Yan, Cheng, Xiaoju, Wu, Jie, Yuan, Chaoyong, He, Tao“…RT-qPCR and Western blot analyses showed that the messenger ribonucleic acid (mRNA) and protein expression of TGF-β1and Smad3 was significantly decreased, and mRNA and protein expression of MMP1 was significantly increased in the RES group than that in the model (P < 0.001) and bare-metal stent groups (P < 0.001). …”
Publicado 2022
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12247por Smith, Ellen S., Whitty, Eric, Yoo, Byunghee, Moore, Anna, Sempere, Lorenzo F., Medarova, Zdravka“…This review focuses on two related classes of short non-coding RNA: microRNAs (miRNAs) and small interfering RNAs (siRNAs). miRNAs are endogenous short RNAs that bind multiple messenger RNAs (mRNAs) and prevent the production of their gene-products, whereas siRNAs are exogenous RNAs that target a single and specific mRNA for degradation. …”
Publicado 2022
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12248por Li, Gaocai, Luo, Rongjin, Zhang, Weifeng, He, Shujie, Wang, Bingjin, Liang, Huaizhen, Song, Yu, Ke, Wencan, Shi, Yunsong, Feng, Xiaobo, Zhao, Kangcheng, Wu, Xinghuo, Zhang, Yukun, Wang, Kun, Yang, Cao“…N6‐methyladenosine (m6A) is the most abundant internal modification in eukaryotic messenger RNAs and is involved in various diseases and cellular processes by modulating mRNA fate. …”
Publicado 2022
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12249“…The gene expression, putative CNA, and relevant tumor information of ESRRs were retrieved. ESRRs messenger RNA (mRNA) expression in BC cell lines was obtained from the Cancer Cell Line Encyclopedia (CCLE). …”
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12250por Kataoka, Tomoya, Kawaki, Yuto, Kito, Yohei, Suzuki, Jun, Mori, Taiki, Hotta, Yuji, Sanagawa, Akimasa, Kawade, Yoshihiro, Maeda, Yasuhiro, Furukawa-Hibi, Yoko, Kimura, Kazunori“…GJG administration significantly decreased PDE-5 and NADPH oxidase-1 messenger RNA expressions in the L-OHP+GJG group. CLINICAL TRANSLATION: This animal model study suggests that GJG might be effective for erectile function in cancer survivors. …”
Publicado 2022
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12251por Deng, Jing, Pan, Weiyi, Ji, Ning, Liu, Na, Chen, Qian, Chen, Jinhuan, Sun, Yutong, Xie, Liang, Chen, Qianming“…BACKGROUND: Damaged and dead cells release cell-free DNA (cfDNA) that activates cyclic GMP–AMP (cGAMP) synthase (cGAS), which leads to the activation of stimulator of interferon genes (STING) via the second messenger cGAMP. STING promotes the production of inflammatory cytokines and type I interferons to induce an inflammatory response. …”
Publicado 2022
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12252por Du, Chang, Bai, Hai-yan, Chen, Jing-jing, Wang, Jia-hui, Wang, Zhi-feng, Zhang, Zhong-hui“…Besides the known productive GRP transcript isoforms, we identified a lot of splicing variants with diverse introns spliced in messenger RNA (mRNA) region coding the glycine-rich (GR) domain. …”
Publicado 2022
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12253por Chen, Ming‐Jenn, Wang, Yao‐Chen, Wang, Lee, Shen, Ching‐Ju, Chen, Chih‐Yi, Lee, Huei“…METHODS: Real‐time reverse transcription‐polymerase chain reaction (RT‐PCR) was performed to evaluate PD‐L1 messenger RNA (mRNA) expression in lung tumors. The prognostic value of PD‐L1 mRNA was assessed by Cox regression model. …”
Publicado 2022
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12254por Li, Jiaxin, Chen, Jieshan, Zhao, Mingyi, Li, Zhetao, Liu, Nanbo, Fang, Heng, Fang, Miaoxian, Zhu, Ping, Lei, Liming, Chen, Chunbo“…Besides, the m(6)A modification-changed and differentially expressed messenger RNA (mRNA) were determined by methylated RNA immunoprecipitation sequencing (MeRIP-seq) and RNA sequencing (RNA-seq) in ALKBH5-overexpressed HL-1 cells. …”
Publicado 2022
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12255“…METHODS: We used microarray technology to establish the differential messenger RNA (mRNA), long non-coding RNA (lncRNA), and circular RNA (circRNA) expression profiles in cord blood exosomes from 3 patients with GDM-M compared with 3 patients with GDM and normal neonatal weight, followed by qPCR validation in an additional 40 patients with GDM. …”
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12256“…Here, whole-transcriptome sequencing was employed to assess the long noncoding RNA (lncRNA), circular RNA (circRNA), microRNA (miRNA), and messenger RNA (mRNA) profiles of GA-Me-treated HCT116 cells. …”
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12257por Lees, Rosemary S., Armistead, Jennifer S., Azizi, Salum, Constant, Edi, Fornadel, Christen, Gimnig, John E., Hemingway, Janet, Impoinvil, Daniel, Irish, Seth R., Kisinza, William, Lissenden, Natalie, Mawejje, Henry D., Messenger, Louisa A., Moore, Sarah, Ngufor, Corine, Oxborough, Richard, Protopopoff, Natacha, Ranson, Hilary, Small, Graham, Wagman, Joseph, Weetman, David, Zohdy, Sarah, Spiers, AngusEnlace del recurso
Publicado 2022
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12258por Carlsen, Ellen Øen, Magnus, Maria C., Oakley, Laura, Fell, Deshayne B., Greve-Isdahl, Margrethe, Kinge, Jonas Minet, Håberg, Siri E.“…EXPOSURES: Maternal messenger RNA COVID-19 vaccination during second or third trimester compared with no vaccination before or during pregnancy. …”
Publicado 2022
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12259por Delaidelli, Alberto, Yao, Betty, Wang, Que Xi, Huang, Yue Zhou, Negri, Gian Luca, Hughes, Christopher, Zhang, Haifeng, Leprivier, Gabriel, Sorensen, Poul“…We pefrormed Multiplexed enhanced Protein Dynamic Mass Spectrometry in eEF2K knockdown MYC-overexpressing D425 MB cells to identify mRNAs selectively translated upon eEF2K activation. Messenger RNAs encoding multiple (9 out of 10 detected) components of the mitochondrial OXPHOS pathway are selectively translated upon eEF2K activation. …”
Publicado 2022
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12260por Fan, Jiaxin, Cao, Shuai, Chen, Mengying, Yao, Qingling, Zhang, Xiaodong, Du, Shuang, Qu, Huiyang, Cheng, Yuxuan, Ma, Shuyin, Zhang, Meijuan, Huang, Yizhou, Zhang, Nan, Shi, Kaili, Zhan, Shuqin“…Differentially expressed long noncoding RNAs, microRNAs, and messenger RNAs (DElncRNAs, DEmiRNAs, and DEmRNAs) between IS patients and controls were identified. …”
Publicado 2022
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