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12341“…BACKGROUND: N6-methyladenosine (m6A) is the most prevalent messenger RNA modification in mammalian cells. However, the disease relevant function of m6A on specific oncogenic long non-coding RNAs (ncRNAs) is not well understood. …”
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12342por Wang, Ranran, Zhou, Kexiang, Xiong, Rongrong, Yang, Yi, Yi, Ruokun, Hu, Jing, Liao, Wei, Zhao, Xin“…Quantitative polymerase chain reaction analysis illustrated that in the gastric tissue of LF-XY18 mice, the messenger RNA (mRNA) expression of occludin, epidermal growth factor (EGF), EGF receptor, vascular EGF, inhibitor kappa-B-α, neuronal nitric oxide synthase, endothelial nitric oxide synthase, cuprozinc superoxide dismutase, manganese superoxide dismutase, and catalase was stronger than that in the control mice, but the mRNA expression of activated B cells (NF-κB), inducible nitric oxide synthase, and cyclooxygenase-2 was weaker than in the control mice. …”
Publicado 2020
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12343por Rajput, Sandeep K., Logsdon, Deirdre M., Kile, Becca, Engelhorn, Heidi J., Goheen, Ben, Khan, Shaihla, Swain, Jason, McCormick, Sue, Schoolcraft, William B., Yuan, Ye, Krisher, Rebecca L.“…OBJECTIVE: To study messenger ribonucleic acid (mRNA) and protein expressions of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) entry receptors (angiotensin 1-converting enzyme 2 [ACE2] and CD147) and proteases (transmembrane serine protease 2 [TMPRSS2] and cathepsin L [CTSL]) in human oocytes, embryos, and cumulus (CCs) and granulosa cells (GCs). …”
Publicado 2021
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12344por Dinas, Petros C., Krase, Argyro, Nintou, Eleni, Georgakopoulos, Alexandros, Granzotto, Marnie, Metaxas, Marinos, Karachaliou, Elena, Rossato, Marco, Vettor, Roberto, Georgoulias, Panagiotis, S. Mayor, Tiago, Koutsikos, John, Athanasiou, Konstantinos, Ioannou, Leonidas G., Gkiata, Paraskevi, Carrillo, Andres E., Koutedakis, Yiannis, Metsios, George S., Jamurtas, Athanasios Z., Chatziioannou, Sofia, Flouris, Andreas D.“…Abbreviations: WAT:White adipose tissue; T(env): Environmental temperature; UCP1: Uncoupling protein one; BAT: Brown adipose tissue; BMI:Body mass index; mRNA: Messenger ribonucleic acid; RCT: Randomized controlled trial; WHR: Waist-to-hip ratio; PRISMA: Preferred Reporting Items for Systematic Reviews and Meta-analyses; PET/CT: Positron Emission Tomography and Computed Tomography; REE: Resting energy expenditure; (18)F-FDG: F(18) fludeoxyglucose; VO(2)peak:Peak oxygen consumption; 1RM: One repetition maximum; SUV(max): Maximum standardized uptake value; Std: Standardized mean difference…”
Publicado 2020
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12345“…BACKGROUND: RNA binding protein motif (RBM3) is associated with radioresistance in nasopharyngeal carcinoma (NPC), and miR-383-5p was predicted to target the 3'-untranslated region (3'UTR) of RBM3 messenger RNA (mRNA). Our study aimed to investigate the role and the mechanisms of miR-383-5p targeting RBM3 in NPC cell proliferation and radioresistance (RR). …”
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12346por Sherer, Morgan L., Lei, Jun, Creisher, Patrick S., Jang, Minyoung, Reddy, Ramya, Voegtline, Kristin, Olson, Sarah, Littlefield, Kirsten, Park, Han-Sol, Ursin, Rebecca L., Ganesan, Abhinaya, Boyer, Theresa, Elsayed, Nada, Brown, Diane M., Walch, Samantha N., Antar, Annukka A.R., Manabe, Yukari C., Jones-Beatty, Kimberly, Golden, William Christopher, Satin, Andrew J., Sheffield, Jeanne S., Pekosz, Andrew, Klein, Sabra L., Burd, Irina“…We measured proinflammatory and placental cytokine messenger RNAs, neonatal Fc receptor expression, and tetanus antibody transfer in maternal and cord blood samples. …”
Publicado 2021
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12347por Lin, Hao, Dong, Beibei, Qi, Liang, Wei, Yingxiang, Zhang, Yusha, Cai, Xiaotian, Zhang, Qi, Li, Jia, Li, Ling“…Quantitative real-time polymerase chain reaction (qRT-PCR) and immunofluorescence staining were used to measure the messenger ribonucleic acid (mRNA) and protein levels of alpha-smooth muscle actin (α-SMA). …”
Publicado 2021
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12348por Bódi, Nikolett, Mezei, Diána, Chakraborty, Payal, Szalai, Zita, Barta, Bence Pál, Balázs, János, Rázga, Zsolt, Hermesz, Edit, Bagyánszki, Mária“…Post-embedding immunogold electron microscopy was applied on ultrathin sections to evaluate the MMP9 and TIMP1 expression in myenteric ganglia and their microenvironment from different gut segments and conditions. The MMP9 and TIMP1 messenger ribonucleic acid (mRNA) level was measured by quantitative polymerase chain reaction. …”
Publicado 2021
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12349por Broseta, José Jesús, Rodríguez-Espinosa, Diana, Rodríguez, Néstor, Mosquera, María del Mar, Marcos, María Ángeles, Egri, Natalia, Pascal, Mariona, Soruco, Erica, Bedini, José Luis, Bayés, Beatriu, Maduell, Francisco“…This study evaluated the humoral and cellular responses to messenger RNA (mRNA) SARS-CoV-2 vaccines in this population. …”
Publicado 2021
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12350por Wang, Hua-Jun, Giambini, Hugo, Chen, Ji-Wen, Wang, Qiu-Shi, Hou, Hui-Ge, Luo, Si-Min, Chen, Jun-Yuan, Zhuang, Teng-Feng, Chen, Yuan-Feng, Wu, Ting-Ting, Zha, Zhen-Gang, Liu, You-Jie, Zheng, Xiao-Fei“…Serum calcium (Ca) and osteocalcin (OCN) levels were compared in the three groups. The messenger ribonucleic acid (mRNA) and protein expression of key regulators for bone metabolism were detected. …”
Publicado 2021
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12351por Thompson, Mark G., Burgess, Jefferey L., Naleway, Allison L., Tyner, Harmony, Yoon, Sarang K., Meece, Jennifer, Olsho, Lauren E.W., Caban-Martinez, Alberto J., Fowlkes, Ashley L., Lutrick, Karen, Groom, Holly C., Dunnigan, Kayan, Odean, Marilyn J., Hegmann, Kurt, Stefanski, Elisha, Edwards, Laura J., Schaefer-Solle, Natasha, Grant, Lauren, Ellingson, Katherine, Kuntz, Jennifer L., Zunie, Tnelda, Thiese, Matthew S., Ivacic, Lynn, Wesley, Meredith G., Mayo Lamberte, Julie, Sun, Xiaoxiao, Smith, Michael E., Phillips, Andrew L., Groover, Kimberly D., Yoo, Young M., Gerald, Joseph, Brown, Rachel T., Herring, Meghan K., Joseph, Gregory, Beitel, Shawn, Morrill, Tyler C., Mak, Josephine, Rivers, Patrick, Poe, Brandon P., Lynch, Brian, Zhou, Yingtao, Zhang, Jing, Kelleher, Anna, Li, Yan, Dickerson, Monica, Hanson, Erika, Guenther, Kyley, Tong, Suxiang, Bateman, Allen, Reisdorf, Erik, Barnes, John, Azziz-Baumgartner, Eduardo, Hunt, Danielle R., Arvay, Melissa L., Kutty, Preeta, Fry, Alicia M., Gaglani, Manjusha“…BACKGROUND: Information is limited regarding the effectiveness of the two-dose messenger RNA (mRNA) vaccines BNT162b2 (Pfizer–BioNTech) and mRNA-1273 (Moderna) in preventing infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and in attenuating coronavirus disease 2019 (Covid-19) when administered in real-world conditions. …”
Publicado 2021
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12352por Su, Weihua, Zhang, Chang, Wang, Dongjiao, Ren, Yongjuan, Sun, Tingting, Feng, Jingfang, Su, Yachun, Xu, Liping, Shi, Mutian, Que, Youxiong“…BACKGROUND: In plants, Calcium (Ca(2+)) acts as a universal messenger in various signal transduction pathways, including responses to biotic and abiotic stresses and regulation of cellular and developmental processes. …”
Publicado 2021
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12353por Aryankalayil, Molykutty J., Martello, Shannon, Bylicky, Michelle A., Chopra, Sunita, May, Jared M., Shankardass, Aman, MacMillan, Laurel, Sun, Landy, Sanjak, Jaleal, Vanpouille-Box, Claire, Eke, Iris, Coleman, C. Norman“…Recent research has highlighted the potential importance of RNAs, including messenger RNAs (mRNAs), microRNAs (miRNAs), and long non-coding RNAs (lncRNAs) as biomarkers to assess radiation damage. …”
Publicado 2021
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12354por Bergwerk, Moriah, Gonen, Tal, Lustig, Yaniv, Amit, Sharon, Lipsitch, Marc, Cohen, Carmit, Mandelboim, Michal, Gal Levin, Einav, Rubin, Carmit, Indenbaum, Victoria, Tal, Ilana, Zavitan, Malka, Zuckerman, Neta, Bar-Chaim, Adina, Kreiss, Yitshak, Regev-Yochay, Gili“…BACKGROUND: Despite the high efficacy of the BNT162b2 messenger RNA vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), rare breakthrough infections have been reported, including infections among health care workers. …”
Publicado 2021
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12355por Bardenheier, Barbara H., Gravenstein, Stefan, Blackman, Carolyn, Gutman, Roee, Sarkar, Indra Neil, Feifer, Richard A., White, Elizabeth M., McConeghy, Kevin, Nanda, Aman, Bosco, Elliott, Mor, Vincent“…SETTING AND PARTICIPANTS: A total of 20,918 nursing home residents who received the first dose of messenger RNA COVID-19 vaccine from December 18, 2020, through February 14, 2021, in 284 facilities within Genesis Healthcare, a large nursing home provider spanning 24 US states. …”
Publicado 2021
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12356por Shen, Wen, Wang, Shukun, Wang, Ruili, Zhang, Yang, Tian, Hong, Yang, Xiaolei, Wei, Wei“…The expression levels of messenger RNAs (mRNAs) and microRNAs (miRNAs) in macrophage cells of M0 (n=7), M1 (n=7), and M2 (n=7) were downloaded from the GEO repository of GSE46903 and GSE51307. …”
Publicado 2021
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12357por Krzywicka, Katarzyna, Heldner, Mirjam R., Sánchez van Kammen, Mayte, van Haaps, Thijs, Hiltunen, Sini, Silvis, Suzanne M., Levi, Marcel, Kremer Hovinga, Johanna A., Jood, Katarina, Lindgren, Erik, Tatlisumak, Turgut, Putaala, Jukka, Aguiar de Sousa, Diana, Middeldorp, Saskia, Arnold, Marcel, Coutinho, Jonathan M., Ferro, José M.“…RESULTS: In all, 213 CVST cases were identified: 187 after AstraZeneca/Oxford (ChAdOx1 nCov‐19) vaccination and 26 after a messenger RNA (mRNA) vaccination (25 with Pfizer/BioNTech, BNT162b2, and one with Moderna, mRNA‐1273). …”
Publicado 2021
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12358por Pilishvili, Tamara, Gierke, Ryan, Fleming-Dutra, Katherine E., Farrar, Jennifer L., Mohr, Nicholas M., Talan, David A., Krishnadasan, Anusha, Harland, Karisa K., Smithline, Howard A., Hou, Peter C., Lee, Lilly C., Lim, Stephen C., Moran, Gregory J., Krebs, Elizabeth, Steele, Mark T., Beiser, David G., Faine, Brett, Haran, John P., Nandi, Utsav, Schrading, Walter A., Chinnock, Brian, Henning, Daniel J., Lovecchio, Frank, Lee, Jane, Barter, Devra, Brackney, Monica, Fridkin, Scott K., Marceaux-Galli, Kaytlynn, Lim, Sarah, Phipps, Erin C., Dumyati, Ghinwa, Pierce, Rebecca, Markus, Tiffanie M., Anderson, Deverick J., Debes, Amanda K., Lin, Michael Y., Mayer, Jeanmarie, Kwon, Jennie H., Safdar, Nasia, Fischer, Marc, Singleton, Rosalyn, Chea, Nora, Magill, Shelley S., Verani, Jennifer R., Schrag, Stephanie J.“…BACKGROUND: The prioritization of U.S. health care personnel for early receipt of messenger RNA (mRNA) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19), allowed for the evaluation of the effectiveness of these new vaccines in a real-world setting. …”
Publicado 2021
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12359por Saiz, Maria Laura, De Diego, Marta L., López-García, Darío, Corte-Iglesias, Viviana, Baragaño Raneros, Aroa, Astola, Ivan, Asensi, Victor, López-Larrea, Carlos, Suarez-Alvarez, Beatriz“…Moreover, the addition of VPA 1 h post-infection with SARS-CoV-2 reduces the production of infectious viruses in a dose-dependent manner without significantly modifying the genomic and subgenomic messenger RNAs (gRNA and sg mRNAs) or protein levels of N protein. …”
Publicado 2021
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12360por Dong, Bo, Wu, Chunli, Li, Shi-Hao, Huang, Lan, Zhang, Chunyang, Wu, Bin, Sheng, Yinliang, Liu, Yafei, Ye, Guanchao, Qi, Yu“…METHODS: In this study, a weighted gene co-expression network analysis was used to screen out messenger RNAs (mRNAs) and non-coding RNAs (ncRNAs) that were co-expressed with m6A regulators. …”
Publicado 2021
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