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12461por He, Dongting, Zou, Tiande, Gai, Xiangrong, Ma, Jideng, Li, Mingzhou, Huang, Zhiqing, Chen, Daiwen“…MicroRNAs (miRNAs) are non-coding small miRNAs ~22 nucleotides in length and play a vital role in muscle development by binding to messenger RNAs (mRNAs). Large White (LW, a lean type pig) and Meishan pigs (MS, a Chinese indigenous obese breed) have significant postnatal phenotype differences in growth rate, muscle mass and meat quality, and these differences are programmed during prenatal muscle development. …”
Publicado 2017
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12462“…To profile their activation responses, NanoString was used to monitor messenger RNA (mRNA) expression of numerous pro- and anti-inflammatory mediators, microglial markers, immunomodulators, and other molecules. …”
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12463por Li, Long-Kai, Wang, Nan, Wang, Wei-Dong, Du, Xiang-Ning, Wen, Xin-Yu, Wang, Ling-Yu, Deng, Yi-Yao, Wang, Da-Peng, Lin, Hong-Li“…METHODS: Rat PMCs were first cultured in a HG (2.5%) culture solution to observe the CF expression level (fluorescein isothiocyanate-lens culinaris agglutinin), we next established a knockdown model of rat PMCs in vitro with Fut8 small interfering RNA (siRNA) to observe whether inhibiting CF decreases the messenger RNA (mRNA) expression and protein expression of Fut8 and reverses EMT status. …”
Publicado 2017
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12464“…Upregulation of miR-488 and miR-920 could suppress MSU-induced IL-1β protein expression in THP-1 cells, but no significant difference in IL-1β messenger RNA levels was observed. Moreover, we found that miR-488 and miR-920 could directly target the 3′-UTR of IL-1β. …”
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12465por Gill, Erin E., Chan, Luisa S., Winsor, Geoffrey L., Dobson, Neil, Lo, Raymond, Ho Sui, Shannan J., Dhillon, Bhavjinder K., Taylor, Patrick K., Shrestha, Raunak, Spencer, Cory, Hancock, Robert E. W., Unrau, Peter J., Brinkman, Fiona S. L.“…RESULTS: The pRNA-Seq library revealed known tRNA, rRNA and transfer-messenger RNA (tmRNA) processing sites, together with previously uncharacterized RNA cleavage events that were found disproportionately near the 5′ ends of transcripts associated with basic bacterial functions such as oxidative phosphorylation and purine metabolism. …”
Publicado 2018
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12466por Donzelli, Sara, Milano, Elisa, Pruszko, Magdalena, Sacconi, Andrea, Masciarelli, Silvia, Iosue, Ilaria, Melucci, Elisa, Gallo, Enzo, Terrenato, Irene, Mottolese, Marcella, Zylicz, Maciej, Zylicz, Alicja, Fazi, Francesco, Blandino, Giovanni, Fontemaggi, Giulia“…RESULTS: We determined that ID4 and macrophage marker CD68 protein expression were significantly associated in a series of triple-negative breast tumours. Interestingly, ID4 messenger RNA (mRNA) levels robustly predicted survival, specifically in the subset of tumours showing high macrophage infiltration. …”
Publicado 2018
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12467por Orr, Mona W., Weiss, Cordelia A., Severin, Geoffrey B., Turdiev, Husan, Kim, Soo-Kyoung, Turdiev, Asan, Liu, Kuanqing, Tu, Benjamin P., Waters, Christopher M., Winkler, Wade C., Lee, Vincent T.“…Bis-(3′-5′)-cyclic dimeric GMP (c-di-GMP) is a bacterial second messenger that regulates processes, such as biofilm formation and virulence. …”
Publicado 2018
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12468por Tziotzios, Christos, Petridis, Christos, Dand, Nick, Ainali, Chrysanthi, Saklatvala, Jake R., Pullabhatla, Venu, Onoufriadis, Alexandros, Pramanik, Rashida, Baudry, David, Lee, Sang Hyuck, Wood, Kristie, Liu, Lu, Seegobin, Seth, Michelotti, Gregory A., Lwin, Su M., Christou, Evangelos A. A., Curtis, Charles J., de Rinaldis, Emanuele, Saxena, Alka, Holmes, Susan, Harries, Matthew, Palamaras, Ioulios, Cunningham, Fiona, Parkins, Gregory, Kaur, Manjit, Farrant, Paul, McDonagh, Andrew, Messenger, Andrew, Jones, Jennifer, Jolliffe, Victoria, Ali, Iaisha, Ardern-Jones, Michael, Mitchell, Charles, Burrows, Nigel, Atkar, Ravinder, Banfield, Cedric, Alexandroff, Anton, Champagne, Caroline, Cooper, Hywel L., Vañó-Galván, Sergio, Molina-Ruiz, Ana Maria, Perez, Nerea Ormaechea, Patel, Girish K., Macbeth, Abby, Page, Melanie, Bryden, Alyson, Mowbray, Megan, Wahie, Shyamal, Armstrong, Keith, Cooke, Nicola, Goodfield, Mark, Man, Irene, de Berker, David, Dunnill, Giles, Takwale, Anita, Rao, Archana, Siah, Tee-Wei, Sinclair, Rodney, Wade, Martin S., Dlova, Ncoza C., Setterfield, Jane, Lewis, Fiona, Bhargava, Kapil, Kirkpatrick, Niall, Estivill, Xavier, Stefanato, Catherine M., Flohr, Carsten, Spector, Timothy, Watt, Fiona M., Smith, Catherine H., Barker, Jonathan N., Fenton, David A., Simpson, Michael A., McGrath, John A.Enlace del recurso
Publicado 2019
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12469por Perrech, Moritz, Dreher, Lena, Röhn, Gabriele, Stavrinou, Pantelis, Krischek, Boris, Toliat, Mohammad, Goldbrunner, Roland, Timmer, Marco“…Hereafter, quantitative expression of IDH1 messenger RNA was assessed using real-time polymerase chain reaction with specific primers for IDH1 mutation and –wt; protein expression was verified by Western Blot analysis and immunohistochemistry. …”
Publicado 2019
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12470por Liang, Xiongfa, Lai, Yongchang, Wu, Weizhou, Chen, Dong, Zhong, Fangling, Huang, Jian, Zeng, Tao, Duan, Xiaolu, Huang, Yapeng, Zhang, Shike, Li, Shujue, Wu, Wenqi“…BACKGROUND: To explore long-non-coding RNA (lncRNA), microRNA (miRNA) and messenger RNA (mRNA) expression profiles and their biological functions in the urine samples in calcium oxalate (CaOx) patients. …”
Publicado 2019
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12471por Perez, Eliana, Viswanathan, Pushpa, Nikiforov, Yuri, Monaco, Sara, Mollen, Kevin, Witchel, Selma“…The DICER1 gene encodes the endoribonuclease protein of the ribonuclease III family which acts post-transcriptionally to downregulate messenger RNAs. Both germline and somatic mutations have been reported (3). …”
Publicado 2019
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12472“…The aim of this study was to elucidate the potential roles of lncRNA, miRNA and messenger RNA (mRNA) ceRNA networks in pulpitis tissues compared to normal control tissues. …”
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12473por Ning, Huanhuan, Wang, Lifei, Zhou, Jie, Lu, Yanzhi, Kang, Jian, Ding, Tianbing, Shen, Lixin, Xu, Zhikai, Bai, Yinlan“…Cyclic di-AMP (c-di-AMP) is a bacterial second messenger which regulates various cellular processes and host immune response. …”
Publicado 2019
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12474por Stica, Caleb, Jeffries, Claire L., Irish, Seth R., Barry, Yaya, Camara, Denka, Yansane, Ismael, Kristan, Mojca, Walker, Thomas, Messenger, Louisa A.Enlace del recurso
Publicado 2019
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12475por Zimta, Alina-Andreea, Cenariu, Diana, Irimie, Alexandru, Magdo, Lorand, Nabavi, Seyed Mohammad, Atanasov, Atanas G., Berindan-Neagoe, Ioana“…MiR-155, miR-144, miR-28, miR-365-1, miR-93, miR-153, miR-27a, miR-142, miR-29-b1, miR-340, and miR-34a, either through direct repression of Nrf2 messenger RNA (mRNA) in a Kelch-like ECH-associated protein 1 (Keap1)-independent manner or by enhancing the Keap1 cellular level, inhibit the Nrf2 activity. …”
Publicado 2019
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12476por Jiang, Yiwen, Xiao, Lianbo, Fu, Wenwei, Tang, Yuexun, Lertnimitphun, Peeraphong, Kim, Nami, Zheng, Changwu, Tan, Hongsheng, Lu, Yue, Xu, Hongxi“…GH inhibited nitric oxide (NO) production, inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression, cytokine interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) production, and messenger RNA (mRNA) expression to attenuate inflammatory responses in lipopolysaccharide (LPS)-induced RAW 264.7 cells or stimulated bone marrow-derived macrophages (BMDMs). …”
Publicado 2020
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12477por Bortone, Federica, Scandiffio, Letizia, Marcuzzo, Stefania, Bonanno, Silvia, Frangiamore, Rita, Motta, Teresio, Antozzi, Carlo, Mantegazza, Renato, Cavalcante, Paola, Bernasconi, Pia“…By real-time PCR, we found that miR-146a expression was significantly downregulated in hyperplastic MG compared to control thymuses; contrariwise, IRAK1, TRAF6, c-REL, and ICOS messenger RNA (mRNA) levels were upregulated and negatively correlated with miR-146a levels. …”
Publicado 2020
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12478por Cansado-Utrilla, Cintia, Jeffries, Claire L., Kristan, Mojca, Brugman, Victor A., Heard, Patrick, Camara, Gnepou, Sylla, Moussa, Beavogui, Abdoul H., Messenger, Louisa A., Irish, Seth R., Walker, ThomasEnlace del recurso
Publicado 2020
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12479por Wang, Xiao-Jian, Xu, Xi-Qi, Sun, Kai, Liu, Ke-Qiang, Li, Su-Qi, Jiang, Xin, Zhao, Qin-Hua, Wang, Lan, Peng, Fu-Hua, Ye, Jue, Wu, Yan, Jiang, Rui, Zhang, Jin, Huang, Wei, Wei, Wen-Bin, Yan, Yi, Li, Jing-Hui, Liu, Qian-Qian, Li, Sheng, Wang, Yong, Zhang, Shu-Yang, Zhang, Xue, Jing, Zhi-Cheng“…The minigene assay indicated that the c.521 + 1G>A variant resulted in aberrant messenger RNA transcripts. The functional studies showed that the 2 missense rare variants (R252Q and A447T) resulted in a decrease in prostacyclin production and increased cell death of pulmonary microvascular endothelial cells. …”
Publicado 2020
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12480“…Detection of thyrotropin-receptor messenger ribonucleic acid (mRNA) and thyroglobulin mRNA transcripts in peripheral blood of patients with thyroid disease: sensitive and specific markers for thyroid cancer. …”
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