“…Sex differences in the development of the normal heart and the prevalence of cardiomyopathies have been reported. …”
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“…Here we find that GPER is required for normal heart rate in zebrafish embryos. Acute exposure to estrogens increased heart rate in wildtype and in ERα and ERβ mutant embryos but not in GPER mutants. …”
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“…METHODS: Patients with CHF (n = 20) and age- and body mass index-matched volunteers (n = 15) with a normal heart function were enrolled. C-reactive protein, N-terminal probrain-type natriuretic peptide (pro-BNP), plasma total peroxide level (PRX), plasma total antioxidant capacity (TAC), oxidative stress index (OSI), leukocyte lipid peroxidation (4-hydroxynonenal; HNE), protein tyrosine nitration (NT), poly(ADP-ribosyl)ation (PARylation), and apoptosis-inducing factor (AIF) translocation were measured in blood samples of fasting subjects. …”
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“…Critically, participants were tested in two conditions: with experimentally induced high heart rate (Exercise) and with normal heart rate (Normal). Participants processed fearful faces (but not disgusted or neutral faces) faster when they were in the Exercise condition than in the Normal condition. …”
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“…We tested 198 case individuals with DS+AVSD, and 211 control individuals with DS and a normal heart, using a custom microarray with dense probes tiled on chromosome 21 for array CGH (aCGH). …”
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“…AIM: This study aims to provide the validity of the fist-heart assumption by correlating the palm and heart diameters while benchmarking it as a reference tool for determining the normal heart size. MATERIALS AND METHOD: Volunteers from the public were recruited during a health fair organised by the school. …”
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“…Mutations in NIPBL result in the dysregulation of many genes responsible for normal heart development likely resulting in the variety of structural cardiac defects observed in the CdLS population.…”
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“…Physical examination revealed: irritability, purple subcutaneous hard nodules, tachypnea, dry spasmodic cough, respiratory rate 45/min, heart rate 110/min, blood pressure 100/60 mmHg, with normal heart sounds, no murmurs, hepatomegaly with hepato-jugular reflux. …”
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“…DIAGNOSES: The tests and examinations showed hypoalbuminemia (26.7 g/L), pulmonary edema, and normal heart function. However, the expected massive proteinuria was absent (1.5 g/24 h). …”
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“…The importance of RyR dysfunction has been recently highlighted with the demonstration that point mutations in RYR2, the gene encoding for the cardiac isoform of the RyR (RyR2), are associated with catecholaminergic polymorphic ventricular tachycardia (CPVT), an arrhythmogenic syndrome characterized by the development of adrenergically-mediated ventricular tachycardia in individuals with an apparently normal heart. Here we summarize the state of the field in regards to the main arrhythmogenic mechanisms triggered by RyR2 channels harboring mutations linked to CPVT. …”
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“…BACKGROUND: Little is known about normal heart rate variability (HRV) in horses during exercise. …”
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“…Although the heart beat rate index, the ratio between low frequency and high frequency (LF/HF), and the respiratory rate were more profoundly affected by the higher and lower air temperatures than moderate air temperatures (P<0.05), this effect was not statistically significant, which may be due to significant reduction in the standard deviation of normal-to normal intervals (SNND) and the root of mean squared difference between adjacent normal heart beat (N-N) intervals (RMSSD) (P>0.05). Conclusion: The results confirmed that the unfavorable air temperatures may considerably affect the physiological responses and the cognitive functions among indoor employees.Therefore, providing them with thermal comfort may improve their performance within indoor environments.…”
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“…Results: Data revealed that VF induced degradation in AF, CF, CO, and SV, which prominently included-variable post-VF capacity for recovery of normal heart rhythm; increased extent of infarcted heart tissue; altered expression of cleaved-caspase-3 suggesting potential for VF-mediated amplification of apoptosis. …”
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“…Ryanodine receptor 2 (RyR2) plays an important role in maintaining the normal heart function, and mutantions can lead to arrhythmia, heart failure and other heart diseases. …”
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“…METHODS: Ten patients with a normal heart (age 35 ± 15 years; 6 men) were studied. …”
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“…Methods: Seventy-two near-normal heart patients were investigated by conducting a cross-sectional study. …”
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“…CASE REPORT: Our patient was a 69-year-old man with a history of symptomatic persistent atrial fibrillation, with an apparently structurally normal heart with subtle regional wall motion abnormalities. …”
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“…In the current study, we sought to determine the impact of TGF-β on fibroblasts transcriptional profiles and assess if exosomes from TGF-β treated fibroblasts could induce a heart failure phenotype in co-cultured cardiomyocytes. METHOD: Normal heart fibroblasts were treated with TGF-β with a final conc. of 2.5 ng/ml in serum free media. …”
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“…However, this attempt failed to recover normal heart function and circulation, although heart pumping was partially restored. …”
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“…The echocardiogram showed a structurally normal heart with normal cardiac function. His tachycardia spontaneously converted to normal sinus rhythm after four hours. …”
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