“…Here, we show that whereas O-Mad2 is monomeric, C-Mad2 forms either symmetric C-Mad2–C-Mad2 (C–C) or asymmetric O-Mad2–C-Mad2 (O–C) dimers. We also report the crystal structure of the symmetric C–C Mad2 dimer, revealing the basis for the ability of unliganded C-Mad2, but not O-Mad2 or liganded C-Mad2, to form symmetric dimers. …”
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“…The analysis of the amplitude histograms by β distributions enabled the estimation of the true single-channel current and the determination of the rate constants of a simple two-state O-C Markov model for the gating in the bursts. The voltage dependence of the gating ratio R = I(true)/I(app) = (k(CO) + k(OC))/k(CO) could be described by exponential functions with different characteristic voltages above or below 50 mM Tl(+). …”
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“…The main component of EhLPPG responsible for NKT cell activation is a diacylated PI, (1-O-[(28∶0)-lyso-glycero-3-phosphatidyl-]2-O-(C16:0)-Ins). IFN-γ production by NKT cells requires the presence of CD1d and simultaneously TLR receptor signalling through MyD88 and secretion of IL-12. …”
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“…RESULTS: We found that ALI/ARDS patients with IAH, as compared to those with normal IAP, were characterized by: a) no differences in gas-exchange, respiratory mechanics, partitioned into its lung and chest wall components, as well as hemodynamics and EVLWI/ITBVI; b) decreased elastance of the respiratory system and the lung, but no differences in alveolar recruitment and oxygenation or hemodynamics, when PEEP was increased at 10 and 15cmH(2)O; c) at higher levels of PEEP, EVLWI was lower in ALI/ARDS patients with IAH as compared with those with normal IAP. …”
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“…Then all the specimens were stored in 10 ml distilled water in test tubes, and then placed in an incubator at 37oC for six weeks. The weight changes of these specimens were measured daily for the first week, and, later, once a week, for the next five weeks, by using an electrical analytical balance. …”
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“…In the absence of SDS, the v(max) of both LipA and LipB were 12.6 U·mg(-1) and 13.3 U·mg(-1) and K(0.5) were 1.8 mM and 1.65 mM, respectively at 96°C and pH(opt)(25ºC)of 9.4-9.6. In the presence of 0.2% SDS, the v(max) increased to 105 U·mg(-1) and 112 U·mg(-1), and K(0.5) values decreased to 200 µM and 140 µM for LipA and LipB, respectively. …”
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“…Specimens were stored at 37ºC for 24h before being submitted to FT-Raman spectrometry (n=3), Knoop microhardness (n=6) and three-point bending (n=6) tests. …”
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“…The asymmetric unit of the title compound [systematic name: aqua­bis(2,4,6-trinitro­phenolato)(3,6,9-trioxaundecane-1,11-diol)gadolinium(III) 2,4,6-trinitro­phenolate methanol hemi­solvate], [Gd(C(6)H(2)N(3)O(7))(2)(C(8)H(18)O(5))(H(2)O)](C(6)H(2)N(3)O(7))·0.5CH(4)O, contains two crystallographically independent Gd(III) complex cations with two uncoordinated picrate anions and one methanol mol­ecule. …”
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“…Each Cr(III )atom is hexa­coordinated by four O and two N atoms from two (hypydc)(2−) fragments, which act as tridentate ligands, in a distorted octa­hedral geometry. The O—Cr—O—C torsion angles between the two planes of the (hypydc)(2−) fragments [−99.81 (17) and 97.77 (17)°] indicate that these two units are almost perpendicular to one another. …”
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“…The title compound, [Ni(C(7)H(3)NO(4))(C(12)H(8)N(2))(H(2)O)]·C(7)H(5)NO(4)·4H(2)O or [Ni(pydc)(phen)(H(2)O)].pydcH(2)·4H(2)O, was obtained by the reaction of nickel(II) nitrate hexa­hydrate with the proton-transfer compound (phenH)(2)(pydc) (phen is 1,10-phenanothroline and pydcH(2) is pyridine-2,6-dicarboxylic acid) in aqueous solution. …”
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“…The geometry of the title mol­ecule points to the enol (OH—C=C—C=N) form as the major tautomer, however two electron-density maxima corresponding to the H atoms of the OH and NH groups, found in the region of a strong intra­molecular N⋯H⋯O hydrogen bond, do not allow the elimination of the presence of the zwitterionic (O(−)—C=C—C=NH(+)) form in the crystal. Refinement of the occupancies of these H atoms gave a 0.61 (7):0.39 (7) ratio of the enolic and zwitterionic forms. …”
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“…In addition, weak C—H⋯O, C—H⋯F, N—H⋯Cl and π–π [centroid–centroid distances = 3.5631 (15), 3.8187 (13), 3.7434 (17) and 3.842 (2) Å] inter­molecular inter­actions are observed, which contribute to crystal packing stability.…”
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“…The double acetate bridge between the copper ions is not coplanar with the CuO(4) equatorial planes, the dihedral angle between the (O—C—O)(2) and O—Cu—O groups being 34.3 (1)°, resulting in a sofa-like conformation for the 8-member bridging loop. …”
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“…In the title compound, [Zn(C(7)H(4)BrO(2))(C(12)H(8)N(2))(2)(H(2)O)](C(7)H(4)BrO(2))·1.5H(2)O, the Zn(II) atom is coordinated by four N atoms from two chelating 1,10-phenanthroline (phen) ligands, one O atom from a 4-bromo­benzoate ligand and one water mol­ecule, completing a distorted ZnN(4)O(2) octa­hedral geometry. …”
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“…Cultures were maintained at 37ºC in a humidified atmosphere containing 5% CO(2) in air. …”
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“…However, in cells containing a thermosensitive eIF4E allele, their inability to grow at 37ºC is suppressed by hyperosmosis, and Cbc1 relocalizes from nucleus to cytoplasm. …”
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“…The common presenting signs and/or symptoms associated with the disease was fever >38.5 ºC (n=85; 72.6%), dry cough (n=81; 69.2%), dyspnea (n=40; 34.5%), tachycardia (n=96; 83.5%) and saturation less than 90% in room air on pulse oximetry (n=65; 55.6%). …”
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“…The vaspin levels were measured from serum that is obtained by centrifigation of blood and stored at -20 (o)C by ELISA method. The length, weight and body mass index of patients were measured. …”
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“…In the title salt co-crystal, [Ag(C(6)H(5)N(2)O)(C(6)H(6)N(2)O)]ClO(4)·[Ag(C(6)H(6)N(2)O)(2)], the asymmetric unit comprises a [Ag(LH)(2)](+) cation, a perchlorate anion and a neutral (LH)AgL mol­ecule, where LH is pyridine-2-carboxaldoxime. …”
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“…Vacuolar-type rotary H(+)-ATPase/synthase (V(o)V(1)) from Thermus thermophilus, composed of nine subunits, A, B, D, F, C, E, G, I, and L, has been reconstituted from individually isolated V(1) (A(3)B(3)D(1)F(1)) and V(o) (C(1)E(2)G(2)I(1)L(12)) subcomplexes in vitro. …”
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